Cholinergic hyperexcitation can be induced by both acute psychological stress and exposure to acetylcholinesterase inhibitors. Both factors are known risk factors for delayed neurodeterioration processes such as Alzheimer’s disease and Parkinson’s disease. Recent publications on the involvement of cholinergic pathways in these and other neurodeterioration syndromes are reviewed.
Tracking cholinergic pathways from psychological and chemical stressors to variable neurodeterioration paradigms
Authors: Kaufer D, Soreq H.
Year of publication: 1999
Journal: Curr Opin Neurol. 1999 Dec;12(6):739-43.
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