Experience-dependent plasticity of mature adult-born neurons

The adult olfactory bulb and hippocampus are continuously supplied with newborn neurons that are thought to possess a capacity for plasticity only at a young neuronal age, mainly during the early stages of integration into the network. We find that the two main types of adult-born neurons in the mouse olfactory bulb undergo experience-dependent plasticity long after maturation and integration, as evidenced by stabilization of synaptic turnover rates. Thus, the potential time window for plasticity of adult-born neurons extends well into maturity.

Authors: Livneh, Y, Mizrahi A.
Year of publication: 2011
Journal: Nature Neuroscience, volume 15, pages 26–28

Link to publication:


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