Hagai Bergman Lab

ELSC Members

Simone and Bernard Guttman Chair in Brain Research

The French Friends Parkinson’s Laboratory

Our research group use physiological (multiple electrode) tools to explore the computation physiology of the basal ganglia, their disorders and therapy. We record the activity of several neurons in the different basal ganglia nuclei during behavioral tasks and over the wake-sleep cycle. We do it before and after induction of disease-like state (e.g., Parkinson’s disease, schizophrenia) in animal models and in human patients undergoing deep brain stimulation (DBS) procedures. Our goal is to provide better understanding of the physiology and pathophysiology of the basal ganglia, and to use this understanding to develop better methods for treatment (eg closed-loop DBS).

Nadav Amir

Undergraduate Student

Gennadiy Fonar

Post Doc

Jing Guang

Post Doc

Lily Iskhakova

Post Doc

Alexander Kaplan

PhD Student

Dan Valsky

PhD Student

Daniel Sand

PhD Student

Noa Rahamim

PhD Student

Odeya Marmor

PhD Student

Pnina Rapel

PhD Student

Shai Heiman Grosberg

PhD Student

Shiran Katabi

PhD Student

Halen Baker

MSc Student

Salam Qukal

MSc Student

Aviv Mizrahi-Kliger

MD-PhD Student

Nir Asch

MD-PhD Student

Orilia Ben Yishay Nizri

MD-PhD Student

Sharon Friman PhD

Managing and Administration

Uri Werner-Reiss

Lab Manager

Shimon Firman

L. Iskhakova, P. Rappel, M. Deffains, G. Fonar, O. Marmor, R. Paz, Z. Israel, R. Eitan & H. Bergman

Modulation of dopamine tone induces frequency shifts in cortico-basal ganglia beta oscillations

Nat Commun 12, 7026 (2021)

Iskhakova, L. P. Rappel, G. Fonar , O. Marmor, R. Paz , Z. Israel , R. Eitan, H. Bergman

Frequency matters: Up- and Down-Regulation of Dopamine Tone Induces Similar Frequency Shifts in Cortico-Basal Ganglia Beta Oscillations

bioRxiv (2021)

Sand D, Arkadir D, Abu Snineh M, Marmor O, Israel Z, Bergman H, Hassin-Baer S, Israeli-Korn S, Peremen Z, Geva AB, Eitan R.

Deep Brain Stimulation Can Differentiate Subregions of the Human Subthalamic Nucleus Area by EEG Biomarkers

Front Syst Neurosci. (2021)

Liu X, Xu Y, Bergman H, Li S, Wang W.

A systematic review of Twiddler’s syndrome: a hardware-related complication of deep brain stimulation

Neurosurg Rev. (2021)

Jing Guang, Halen Baker, Orilia Ben-Yishay Nizri, Shimon Firman, Uri Werner-Reiss, Vadim Kapuller, Zvi Israel & Hagai Bergman

Toward asleep DBS: cortico-basal ganglia spectral and coherence activity during interleaved propofol/ketamine sedation mimics NREM/REM sleep activity

npj Parkinson’s Disease (2021)

Benady A, Zadik S, Eimerl D, Heymann S, Bergman H, Israel Z, Raz A.

Sedative drugs modulate the neuronal activity in the subthalamic nucleus of parkinsonian patients

Sci Rep. (2020)

Nir Asch, Yehuda Herschman, Rotem Maoz, Carmel Aurbach-Asch, Dan Valsky, Muneer Abu-Snineh, David Arkadir, Eduard Linetsky, Renana Eitan, Odeya Marmor, Hagai Bergman and Zvi Israel;

Independently Together: Subthalamic Theta and Beta Opposite Roles in Predicting Parkinson’s Tremor

Brain communications (2020)

Valsky D, Heiman Grosberg S, Israel Z, Boraud T, Bergman H, Deffains M.

What is the true discharge rate and pattern of the striatal projection neurons in Parkinson’s disease and Dystonia?

Elife (2020)

Mizrahi-Kliger, A. D., A. Kaplan, Z. Israel, M. Deffains, and H. Bergman.

‘Basal ganglia beta oscillations during sleep underlie Parkinsonian insomnia

Proc Natl Acad Sci U S A. (2020)

Kaplan, A., Mizrahi-Kliger, A.D., Israel, Z. et al.

Dissociable roles of ventral pallidum neurons in the basal ganglia reinforcement learning network

Nat Neurosci 23, 556–564 (2020)

Rappel P, Grosberg S, Arkadir D, Linetsky E, Abu Snineh M, Bick AS, Tamir I, Valsky D, Marmor O, Abo Foul Y, Peled O, Gilad M, Daudi C, Ben-Naim S, Bergman H, Israel Z, Eitan R.

Theta‐alpha oscillations characterize emotional subregion in the human ventral subthalamic nucleus

Movement Disorders (2019) (2019)

Valsky D, Blackwell K, Tamir I, Eitan R, Bergman H, Israel Z

Real-time machine learning classification of pallidal borders during deep brain stimulation surgery

Journal of Neural Engineering (2019)

Marc Deffains, Hagai Bergma

Parkinsonism & Related Disorders (2019)

Ben Engelhard, Ran Darshan, Nofar Ozeri-Engelhard, Zvi Israel, Uri Werner-Reiss, David Hansel, Hagai Bergman, Eilon Vaadia

Neuronal activity and learning in local cortical networks are modulated by the action-perception state

bioRxiv (2019)

Marmor O, Rappel P, Valsky D, Bick AS, Arkadir D, Linetzky E, Peled O, Tamir I, Bergman H, Israel Z, Eitan R

Movement context modulates neuronal activity in motor and limbic-associative domains of the human parkinsonian subthalamic nucleus

Neurobiology of Disease, 104716 (2019)

Shamir RR, Duchin Y, Kim J, Patriat R, Marmor O, Bergman H, Vitek JL, Sapiro G, Bick A, Eliahou R, Eitan R, Israel Z, Harel N

Microelectrode Recordings Validate the Clinical Visualization of Subthalamic-Nucleus Based on 7T Magnetic Resonance Imaging and Machine Learning for Deep Brain Stimulation Surgery

Neurosurgery, 84, no. 3, 749–757 (2019)

Eitan R, Arkadir D, Linetsky E, Bick AS, Gilad M, Freedman S, Bergman H, Israel Z

Deep brain stimulation for obsessive compulsive disorder: case report of the first OCD patient in Israel

Harefua, Issue 158, Volume 7, Pages 418-422 (2019)

Snineh MA, Hajyahya A, Linetsky E, Eitan R, Bergman H, Israel Z, Arkadir D

A Real-Life Search for the Optimal Set of Conversion Factors to Levodopa-Equivalent-Dose in Parkinson’s Disease Patients on Polytherapy

Journal of Parkinson's Disease (2019)

Menchón, J.M., Real, E., Alonso, P. et al.

A prospective international multi-center study on safety and efficacy of deep brain stimulation for resistant obsessive-compulsive disorder

Mol Psychiatry (2019)

Deffains M, Iskhakova L, Katabi S, Israel Z, Bergman H.

Longer β oscillatory episodes reliably identify pathological subthalamic activity in Parkinsonism

Movement disorders. 33(10):1609-1618 (2018)

Mizrahi-Kliger, Kaplan, Israel and Bergman

De-synchronization of slow oscillations in the basal ganglia during natural sleep

PNAS, 115 (18) E4274-E4283 (2018)

Wichmann T, Bergman H, DeLong MR

Basal ganglia, movement disorders and deep brain stimulation: advances made through non-human primate research

Journal of Neural Transmission, Volume 125, Issue 3, pp 419–430 (2018)

Marmor O, Valsky D, Joshua M, Bick AS, Arkadir D, Tamir I, Bergman H, Israel Z, Eitan R.

Local vs. volume conductance activity of field potentials in the human subthalamic nucleus

Journal of Neurophysiology 117(6):2140-2151 (2017)

Ashkan K, Rogers P, Bergman H, Ughratdar I

Insights into the mechanisms of deep brain stimulation

Nature Reviews Neurology, volume 13, pages 548–554 (2017)

Deffains, M, Iskhakova L, Bergman H.

Stop and Think about Basal Ganglia Functional Organization: The Pallido-Striatal “Stop” Route.

Neuron, Volume 89, Issue 2, Pages 237-239 (2016)

Israel, Z, Bergman H.

Location, location, location: Validating the position of deep brain stimulation electrodes.

Movement disorders, Volume 31, Issue 3, Pages 259-259 (2016)

Deffains, Iskhakova, Katabi, Haber, Israel & Bergman

Subthalamic, not striatal, activity correlates with basal ganglia downstream activity in normal and parkinsonian monkeys

eLife 2016;5:e16443 (2016)

Schechtman, E, Noblejas M I, Mizrahi AD, Dauber O, Bergman H.

Pallidal spiking activity reflects learning dynamics and predicts performance.

PNAS, 113 (41) E6281-E6289 (2016)

Soreq, L., Salomonis, N., Guffanti, A., Bergman, H., Israel, Z. and Soreq, H.

Whole transcriptome RNA sequencing data from blood leukocytes derived from Parkinson’s disease patients prior to and following deep brain stimulation treatment

Genomics Data, Volume 3, Pages 57-60 (2015)

Soreq, L., Guffanti, A., Salomonis, N., Simchovitz, A., Israel, Z., Bergman, H. and Soreq, H.

Long Non-Coding RNA and Alternative Splicing Modulations in Parkinson’s Leukocytes Identified by RNA Sequencing

Plos computational biology, 10(3):e1003517 (2014)

Soreq, L., Salomonis, N., Bronstein, M., Greenberg, D.S., Israel, Z. Bergman, H. and Soreq, H.

Small RNA sequencing-microarray analyses in Parkinson leukocytes reveal deep brain stimulation-induced splicing changes that classify brain region transcriptomes

Frontiers in Molecular Neuroscience, 6, article 10, 20 pp (2013)

Engelhard B, Ozeri N, Israel Z, Bergman H, Vaadia E.

Inducing Gamma Oscillations and Precise Spike Synchrony by Operant Conditioning via Brain-Machine Interface

Neuron; 77(2):361-75 (2013)

Adler A, Finkes I, Katabi S, Prut Y, Bergman H

Encoding by Synchronization in the Primate Striatum

Journal of Neuroscience, 33 (11) 4854-4866 (2013)

Adler A, Katabi S, Finkes I, Prut Y, Bergman H

Different correlation patterns of cholinergic and GABAergic interneurons with striatal projection neurons

Frontiers in Systems Neuroscience, 7:47 (2013)

Soreq, L., Bergman, H., Israel, Z. and Soreq, H.

Deep brain stimulation modulates nonsense-mediated RNA decay in Parkinson’s patients leukocytes

BMC Genomics, 14:478 (2013)

Adler A, Katabi S, Finkes I, Israel Z, Prut Y, Bergman H.

Temporal convergence of dynamic cell assemblies in the striato-pallidal network

Journal of Neuroscience, 32 (7) 2473-2484; (2012)

R.R. Shamir, A. Zaidel, L. Joskowicz, H. Bergan, Z. Israel

Microelectrode Recording Duration and Spatial Density Constraints for Automatic Targeting of the Subthalamic Nucleus

Stereotactic and Functional Neurosurgery 90(5):325-335 (2012)

Soreq, L., Ben-Shaul, Y., Israel, Z., Bergman, H. and Soreq, H.

Meta-analysis of genetic and environmental Parkinson’s disease models reveals a common role of mitochondrial protection pathways

Neurobiology of Disease, Volume 45, Issue 3, Pages 1018-1030 (2012)

Soreq, L., Greenberg, D.S., Bergman, H., Israel, Z. and Soreq, H.

Exon Arrays Reveal Alternative Splicing Aberrations in Parkinson’s Disease Leukocytes

Neurodegenerative Disease 10, 203-206 (2012)

Soreq, L., Israel, Z., Greenberg, D.S., Bergman, H. and Soreq, H.

Deep brain stimulation induces rapidly reversible transcript changes in Parkinson’s leucocytes

Journal of cellular and molecular medicine 16, 1496-1507 (2012)

BenMoyal-Segal, L., Soreq, L., Ben-Shaul, Y., Ben-Ari, S., Ben-Moshe, T., Aviel, S., Bergman, H. and Soreq, H.

Adaptive Alternative Splicing Correlates with Less Environmental Risk of Parkinsonism

Neurodegenerative Disease 9, 87-98 (2012)

Rosin B, Slovik M, Mitelman R, Rivlin-Etzion M, Haber SN, Israel Z, Vaadia E, Bergman H.

Closed-loop deep brain stimulation is superior in ameliorating Parkinsonism

Neuron, 72(2), 370-384 (2011)

Zaidel A, Spivak A, Grieb B, Bergman H, Israel Z.

Subthalamic span of beta-oscillations predicts deep brain stimulation efficacy for Parkinson’s patients

Brain. 133(Pt 7):2007-21 (2010)

Joshua, M. Adler, A. and Bergman, H.

Novelty encoding by the output neurons of the basal ganglia

Frontiers in Systems Neuroscience 8;3:2 (2010)

Adler, A, Joshua M, Rivlin-Etzion M, Mitelman R, Marmor O, Prut Y, Bergman H.

Neurons in both pallidal segments change their firing properties similarly prior to closure of the eyes.

Journal of neurophysiology. 103(1):346-59 (2010)

Joshua, M, Adler, A. and Bergman, H.

The dynamics of dopamine in control of motor behavior

Current Opinion in Neurobiology, Volume 19, Issue 6, Pages 615-620 (2009)

Joshua M, Adler A, Prut Y, Vaadia E, Wickens JR, Bergman H.

Synchronization of midbrain dopaminergic neurons is enhanced by rewarding events

Neuron. 62(5):695-704 (2009)

Joshua, M, Adler A, Rosin B, Vaadia E, Bergman H.

Encoding of probabilistic rewarding and aversive events by pallidal and nigral neurons.

Journal of neurophysiology, Volume 101, Issue 2, Pages 758-772 (2009)

Mitelman, R, Joshua M, Adler A, Bergman H.

A noninvasive, fast and inexpensive tool for the detection of eye open/closed state in primates

Journal of Neuroscience Methods, Volume 178, Issue 2, Pages 350-356 (2009)

Joshua, M, Adler A, Mitelman R, Vaadia E, Bergman H.

Midbrain dopaminergic neurons and striatal cholinergic interneurons encode the difference between reward and aversive events at different epochs of probabilistic classical conditioning trials.

Journal of Neuroscience, 28 (45) 11673-11684 (2008)

Rivlin-Etzion M, Marmor O, Saban G, Rosin B, Haber SN, Vaadia E, Prut Y, Bergman H.

Low-pass filter properties of basal ganglia cortical muscle loops in the normal and MPTP primate model of parkinsonism

J Neurosci. 2008 Jan 16;28(3):633-49. (2008)

Lilach Soreq, Adi Gilboa-Geffen, Sonia Berrih-Aknin, Paul Lacoste, Ariel Darvasi, Eyal Soreq, Hagai Bergman, and Hermona Soreq

Identifying alternative hyper-splicing signatures in MG-thymoma by exon arrays

PLoS One. 2008; 3(6): e2392. (2008)

Parush N, Arkadir D, Nevet A, Morris G, Tishby N, Nelken I, Bergman H.

Encoding by response duration in the basal ganglia

J Neurophysiol. 2008 Dec;100(6):3244-52. (2008)

Neta Zach, Dorrit Inbar, Yael Grinvald, Hagai Bergman and Eilon Vaadia

Emergence of novel representations in primary motor cortex and premotor neurons during associative learning

Journal of Neuroscience 17 September 2008, 28 (38) 9545-9556; (2008)

Soreq L, Israel Z, Bergman H, Soreq H.

Advanced microarray analysis highlights modified neuro-immune signaling in nucleated blood cells from Parkinson’s disease patients

J Neuroimmunol. 2008 Sep 15;201-202:227-36. (2008)

Elias, S, Joshua M, Goldberg JA, Heimer G, Arkadir D, Morris G, Bergman H.

Statistical properties of pauses of the high-frequency discharge neurons in the external segment of the globus pallidus.

Journal of Neuroscience, 27 (10) 2525-2538 (2007)

Joshua, M, Elias S, Levine O, Bergman H.

Quantifying the isolation quality of extracellularly recorded action potentials.

Journal of Neuroscience Methods, Volume 163, Issue 2, Pages 267-282 (2007)

Morris, Nevet, Arkadir, Vaadia and Bergman

Midbrain dopamine neurons encode decisions for future action

Nature Neuroscience volume 9, pages 1057–1063 (2006)

Ben-Shaul Y, Benmoyal-Segal L, Ben-Ari S, Bergman H, Soreq H.

Adaptive acetylcholinesterase splicing patterns attenuate 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinsonism in mice

Eur J Neurosci. 2006 Jun;23(11):2915-22. (2006)

Ben-Shaul Y, Bergman H, Soreq H.

Identifying subtle interrelated changes in functional gene categories using continuous measures of gene expression

Bioinformatics. 2005 Apr 1;21(7):1129-37. Epub 2004 Nov 18. (2005)

Rony Paz, Chen Natan, Thomas Boraud, Hagai Bergman and Eilon Vaadia

Emerging patterns of neuronal responses in supplementary and primary motor areas during sensorimotor adaptation

Journal of Neuroscience 23 November 2005, 25 (47) 10941-10951; (2005)

Paz R, Nathan C, Boraud T, Bergman H, Vaadia E.

Acquisition and generalization of visuomotor transformations by nonhuman primates

Exp Brain Res. 2005 Feb;161(2):209-19. (2005)

Goldberg JA, Rokni U, Boraud T, Vaadia E, Bergman H.

Spike synchronization in the cortex/basal-ganglia networks of Parkinsonian primates reflects global dynamics of the local field potentials

J Neurosci. 2004 Jun 30;24(26):6003-10. (2004)

Arkadir D, Morris G, Vaadia E, Bergman H.

Independent coding of movement direction and reward prediction by single pallidal neurons

J Neurosci. 2004 Nov 10;24(45):10047-56. (2004)

Bar-Gad I, Elias S, Vaadia E, Bergman H.

Complex locking rather than complete cessation of neuronal activity in the globus pallidus of a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated primate in response to pallidal microstimulation

J Neurosci. 2004 Aug 18;24(33):7410-9. (2004)

Morris G, Arkadir D, Nevet A, Vaadia E, Bergman H.

Coincident but distinct messages of midbrain dopamine and striatal tonically active neurons

Neuron. 43(1):133-43. (2004)

Paz R, Boraud T, Natan C, Bergman H, Vaadia E.

Preparatory activity in motor cortex reflects learning of local visuomotor skills

Nat Neurosci. 2003 Aug;6(8):882-90. (2003)

Bar-Gad I, Morris G, Bergman H.

Information processing, dimensionality reduction and reinforcement learning in the basal ganglia

Prog Neurobiol. 71(6):439-73. (2003)

Bar-Gad I, Heimer G, Ritov Y, Bergman H.

Functional correlations between neighboring neurons in the primate Globus Pallidus are weak or nonexistent

J Neurosci. 23(10):4012-6. (2003)

A. Gribova, O. Donchin, H. Bergman, E. Vaadia, S. Cardoso de Oliveira

Timing of bimanual movements in human and non-human primates in relation to neuronal activity in primary motor cortex and supplementary motor area

Experimental Brain Research October 2002, Volume 146, Issue 3, pp 322–335 (2002)

Donchin O, Gribova A, Steinberg O, Mitz AR, Bergman H, Vaadia E.

Single-unit activity related to bimanual arm movements in the primary and supplementary motor cortices

J Neurophysiol. 2002 Dec;88(6):3498-517. (2002)

Steinberg O, Donchin O, Gribova A, Cardosa de Oliveira S, Bergman H, Vaadia E.

Neuronal populations in primary motor cortex encode bimanual arm movements

Eur J Neurosci. 2002 Apr;15(8):1371-80. (2002)

Goldberg JA, Boraud T, Maraton S, Haber SN, Vaadia E, Bergman H.

Enhanced synchrony among primary motor cortex neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine primate model of Parkinson’s disease

J Neurosci. 2002 Jun 1;22(11):4639-53. (2002)

Cardoso de Oliveira S, Gribova A, Donchin O, Bergman H, Vaadia E.

Neural interactions between motor cortical hemispheres during bimanual and unimanual arm movements

Eur J Neurosci. 2001 Dec;14(11):1881-96. (2001)

O. Donchin, A. Gribova, O. Steinberg, H. Bergman, Cardoso S. de Oliveira, E. Vaadia

Local field potentials related to bimanual movements in the primary and supplementary motor cortices

Experimental Brain Research 140(1):46-55 (2001)

Bar-Gad I, Ritov Y, Vaadia E, Bergman H.

Failure in identification of overlapping spikes from multiple neuron activity causes artificial correlations

J Neurosci Methods. 2001 May 30;107(1-2):1-13. (2001)

Raz A, Frechter-Mazar V, Feingold A, Abeles M, Vaadia E, Bergman H.

Activity of pallidal and striatal tonically active neurons is correlated in mptp-treated monkeys but not in normal monkeys

J Neurosci. 2001 Feb 1;21(3):RC128. (2001)

Raz A, Vaadia E, Bergman H.

Firing patterns and correlations of spontaneous discharge of pallidal neurons in the normal and tremulous MPTP Vervet model of Parkinsonism

J Neurosci. 20(22):8559-71. (2000)

Slovin H, Abeles M, Vaadia E, Haalman I, Prut Y, Bergman H.

Frontal cognitive impairments and saccadic deficits in low-dose MPTP-treated monkeys

J Neurophysiol. 1999 Feb;81(2):858-74. (1999)

Bergman H, Raz A, Feingold A, Nini A, Nelken I, Hansel D, Ben-Pazi H, Reches A.

Physiology of MPTP tremor

Mov Disord. 1998;13 Suppl 3:29-34. (1998)

Bergman H, Feingold A, Nini A, Raz A, Slovin H, Abeles M, Vaadia E.

Physiological aspects of information processing in the basal ganglia of normal and parkinsonian primates

Trends Neurosci. 1998 Jan;21(1):32-8. (1998)

Prut Y, Vaadia E, Bergman H, Haalman I, Slovin H, Abeles M.

Spatiotemporal structure of cortical activity: properties and behavioral relevance

J Neurophysiol. 1998 Jun;79(6):2857-74. (1998)

Raz A, Feingold A, Zelanskaya V, Vaadia E, Bergman H.

Neuronal synchronization of tonically active neurons in the striatum of normal and Parkinsonian primates

J Neurophysiol; 76(3):2083-8. (1996J Neurophysiol; 76(3):2083-8.)

Seidemann E, Meilijson I, Abeles M, Bergman H, Vaadia E.

Simultaneously recorded single units in the frontal cortex go through sequences of discrete and stable states in monkeys performing a delayed localization task

J Neurosci. 1996 Jan 15;16(2):752-68. (1996)

Nini A, Feingold A, Slovin H, Bergman H.

Neurons in the globus pallidus do not show correlated activity in the normal monkey, but phase-locked oscillations appear in the MPTP model of Parkinsonism

J Neurophysiol; 74(4):1800-5. (1995)

Vaadia E, Haalman I, Abeles M, Bergman H, Prut Y, Slovin H, Aertsen A.

Dynamics of neuronal interactions in monkey cortex in relation to behavioural events

Nature. 1995 Feb 9;373(6514):515-8. (1995)

Abeles M, Bergman H, Gat I, Meilijson I, Seidemann E, Tishby N, Vaadia E.

Cortical activity flips among quasi-stationary states

Proc Natl Acad Sci U S A. 1995 Sep 12;92(19):8616-20. (1995)

Bergman H, Wichmann T, Karmon B, DeLong MR.

The primate subthalamic nucleus. II. Neuronal activity in the MPTP model of parkinsonism

J. of Neurophysiology. 72: 507-520 (1994)

Abeles M, Prut Y, Bergman H, Vaadia E.

Synchronization in neuronal transmission and its importance for information processing

Prog Brain Res. 1994;102:395-404. (1994)

Ahissar M, Ahissar E, Bergman H, Vaadia E.

Encoding of sound-source location and movement: activity of single neurons and interactions between adjacent neurons in the monkey auditory cortex

J Neurophysiol. 1992 Jan;67(1):203-15. (1992)

Ahissar E, Vaadia E, Ahissar M, Bergman H, Arieli A, Abeles M.

Dependence of cortical plasticity on correlated activity of single neurons and on behavioral context

Science. 1992 Sep 4;257(5075):1412-5. (1992)

Aertsen A, Vaadia E, Abeles M, Ahissar E, Bergman H, Karmon B, Lavner Y, Margalit E, Nelken I, Rotter S.

Neural interactions in the frontal cortex of a behaving monkey: signs of dependence on stimulus context and behavioral state

J Hirnforsch. 1991;32(6):735-43. (1991)

H Bergman, T Wichmann, MR DeLong

Reversal of experimental parkinsonism by lesions of the subthalamic nucleus

Science, Vol. 249, Issue 4975, pp. 1436-1438 (1990)

Vaadia E, Bergman H, Abeles M.

Neuronal activities related to higher brain functions–theoretical and experimental implications

IEEE Trans Biomed Eng. 1989 Jan;36(1):25-35. (1989)

Honors:
Michael Bruno Memorial Award in 2003

Baruch Rapport prize for excellence in bio-medical research in 2013

the Rotchild prize in life science 2016

Website:
https://basalganglia.huji.ac.il

Gallery:

Hagai Bergman

Professor

Email: hagaibe@ekmd.huji.ac.il

Phone: +972-2-6757388

Fax: +972-2-6439736

Hagai Bergman

@hb_cell

Address: The Edmond and Lily Safra Center for Brain Sciences
The Suzanne and Charles Goodman Brain Sciences Building,
Level 3, Room 1304 Edmond J. Safra Campus,
The Hebrew University of Jerusalem, 9190401

https://basalganglia.huji.ac.il

Simone and Bernard Guttman Chair in Brain Research

The French Friends Parkinson’s Laboratory

People

Nadav Amir

Undergraduate Student

Gennadiy Fonar

Post Doc

Jing Guang

Post Doc

Lily Iskhakova

Post Doc

Alexander Kaplan

PhD Student

Dan Valsky

PhD Student

Daniel Sand

PhD Student

Noa Rahamim

PhD Student

Odeya Marmor

PhD Student

Pnina Rapel

PhD Student

Shai Heiman Grosberg

PhD Student

Shiran Katabi

PhD Student

Halen Baker

MSc Student

Salam Qukal

MSc Student

Aviv Mizrahi-Kliger

MD-PhD Student

Nir Asch

MD-PhD Student

Orilia Ben Yishay Nizri

MD-PhD Student

Sharon Friman PhD

Managing and Administration

Uri Werner-Reiss

Lab Manager

Shimon Firman

Publications

L. Iskhakova, P. Rappel, M. Deffains, G. Fonar, O. Marmor, R. Paz, Z. Israel, R. Eitan & H. Bergman

Modulation of dopamine tone induces frequency shifts in cortico-basal ganglia beta oscillations

Nat Commun 12, 7026 (2021)

Iskhakova, L. P. Rappel, G. Fonar , O. Marmor, R. Paz , Z. Israel , R. Eitan, H. Bergman

Frequency matters: Up- and Down-Regulation of Dopamine Tone Induces Similar Frequency Shifts in Cortico-Basal Ganglia Beta Oscillations

bioRxiv (2021)

Sand D, Arkadir D, Abu Snineh M, Marmor O, Israel Z, Bergman H, Hassin-Baer S, Israeli-Korn S, Peremen Z, Geva AB, Eitan R.

Deep Brain Stimulation Can Differentiate Subregions of the Human Subthalamic Nucleus Area by EEG Biomarkers

Front Syst Neurosci. (2021)

Liu X, Xu Y, Bergman H, Li S, Wang W.

A systematic review of Twiddler’s syndrome: a hardware-related complication of deep brain stimulation

Neurosurg Rev. (2021)

Jing Guang, Halen Baker, Orilia Ben-Yishay Nizri, Shimon Firman, Uri Werner-Reiss, Vadim Kapuller, Zvi Israel & Hagai Bergman

Toward asleep DBS: cortico-basal ganglia spectral and coherence activity during interleaved propofol/ketamine sedation mimics NREM/REM sleep activity

npj Parkinson’s Disease (2021)

Benady A, Zadik S, Eimerl D, Heymann S, Bergman H, Israel Z, Raz A.

Sedative drugs modulate the neuronal activity in the subthalamic nucleus of parkinsonian patients

Sci Rep. (2020)

Nir Asch, Yehuda Herschman, Rotem Maoz, Carmel Aurbach-Asch, Dan Valsky, Muneer Abu-Snineh, David Arkadir, Eduard Linetsky, Renana Eitan, Odeya Marmor, Hagai Bergman and Zvi Israel;

Independently Together: Subthalamic Theta and Beta Opposite Roles in Predicting Parkinson’s Tremor

Brain communications (2020)

Valsky D, Heiman Grosberg S, Israel Z, Boraud T, Bergman H, Deffains M.

What is the true discharge rate and pattern of the striatal projection neurons in Parkinson’s disease and Dystonia?

Elife (2020)

Mizrahi-Kliger, A. D., A. Kaplan, Z. Israel, M. Deffains, and H. Bergman.

‘Basal ganglia beta oscillations during sleep underlie Parkinsonian insomnia

Proc Natl Acad Sci U S A. (2020)

Kaplan, A., Mizrahi-Kliger, A.D., Israel, Z. et al.

Dissociable roles of ventral pallidum neurons in the basal ganglia reinforcement learning network

Nat Neurosci 23, 556–564 (2020)

Rappel P, Grosberg S, Arkadir D, Linetsky E, Abu Snineh M, Bick AS, Tamir I, Valsky D, Marmor O, Abo Foul Y, Peled O, Gilad M, Daudi C, Ben-Naim S, Bergman H, Israel Z, Eitan R.

Theta‐alpha oscillations characterize emotional subregion in the human ventral subthalamic nucleus

Movement Disorders (2019) (2019)

Valsky D, Blackwell K, Tamir I, Eitan R, Bergman H, Israel Z

Real-time machine learning classification of pallidal borders during deep brain stimulation surgery

Journal of Neural Engineering (2019)

Marc Deffains, Hagai Bergma

Parkinsonism & Related Disorders (2019)

Ben Engelhard, Ran Darshan, Nofar Ozeri-Engelhard, Zvi Israel, Uri Werner-Reiss, David Hansel, Hagai Bergman, Eilon Vaadia

Neuronal activity and learning in local cortical networks are modulated by the action-perception state

bioRxiv (2019)

Marmor O, Rappel P, Valsky D, Bick AS, Arkadir D, Linetzky E, Peled O, Tamir I, Bergman H, Israel Z, Eitan R

Movement context modulates neuronal activity in motor and limbic-associative domains of the human parkinsonian subthalamic nucleus

Neurobiology of Disease, 104716 (2019)

Shamir RR, Duchin Y, Kim J, Patriat R, Marmor O, Bergman H, Vitek JL, Sapiro G, Bick A, Eliahou R, Eitan R, Israel Z, Harel N

Microelectrode Recordings Validate the Clinical Visualization of Subthalamic-Nucleus Based on 7T Magnetic Resonance Imaging and Machine Learning for Deep Brain Stimulation Surgery

Neurosurgery, 84, no. 3, 749–757 (2019)

Eitan R, Arkadir D, Linetsky E, Bick AS, Gilad M, Freedman S, Bergman H, Israel Z

Deep brain stimulation for obsessive compulsive disorder: case report of the first OCD patient in Israel

Harefua, Issue 158, Volume 7, Pages 418-422 (2019)

Snineh MA, Hajyahya A, Linetsky E, Eitan R, Bergman H, Israel Z, Arkadir D

A Real-Life Search for the Optimal Set of Conversion Factors to Levodopa-Equivalent-Dose in Parkinson’s Disease Patients on Polytherapy

Journal of Parkinson’s Disease (2019)

Menchón, J.M., Real, E., Alonso, P. et al.

A prospective international multi-center study on safety and efficacy of deep brain stimulation for resistant obsessive-compulsive disorder

Mol Psychiatry (2019)

Deffains M, Iskhakova L, Katabi S, Israel Z, Bergman H.

Longer β oscillatory episodes reliably identify pathological subthalamic activity in Parkinsonism

Movement disorders. 33(10):1609-1618 (2018)

Mizrahi-Kliger, Kaplan, Israel and Bergman

De-synchronization of slow oscillations in the basal ganglia during natural sleep

PNAS, 115 (18) E4274-E4283 (2018)

Wichmann T, Bergman H, DeLong MR

Basal ganglia, movement disorders and deep brain stimulation: advances made through non-human primate research

Journal of Neural Transmission, Volume 125, Issue 3, pp 419–430 (2018)

Marmor O, Valsky D, Joshua M, Bick AS, Arkadir D, Tamir I, Bergman H, Israel Z, Eitan R.

Local vs. volume conductance activity of field potentials in the human subthalamic nucleus

Journal of Neurophysiology 117(6):2140-2151 (2017)

Ashkan K, Rogers P, Bergman H, Ughratdar I

Insights into the mechanisms of deep brain stimulation

Nature Reviews Neurology, volume 13, pages 548–554 (2017)

Deffains, M, Iskhakova L, Bergman H.

Stop and Think about Basal Ganglia Functional Organization: The Pallido-Striatal “Stop” Route.

Neuron, Volume 89, Issue 2, Pages 237-239 (2016)

Israel, Z, Bergman H.

Location, location, location: Validating the position of deep brain stimulation electrodes.

Movement disorders, Volume 31, Issue 3, Pages 259-259 (2016)

Deffains, Iskhakova, Katabi, Haber, Israel & Bergman

Subthalamic, not striatal, activity correlates with basal ganglia downstream activity in normal and parkinsonian monkeys

eLife 2016;5:e16443 (2016)

Schechtman, E, Noblejas M I, Mizrahi AD, Dauber O, Bergman H.

Pallidal spiking activity reflects learning dynamics and predicts performance.

PNAS, 113 (41) E6281-E6289 (2016)

Soreq, L., Salomonis, N., Guffanti, A., Bergman, H., Israel, Z. and Soreq, H.

Whole transcriptome RNA sequencing data from blood leukocytes derived from Parkinson’s disease patients prior to and following deep brain stimulation treatment

Genomics Data, Volume 3, Pages 57-60 (2015)

Soreq, L., Guffanti, A., Salomonis, N., Simchovitz, A., Israel, Z., Bergman, H. and Soreq, H.

Long Non-Coding RNA and Alternative Splicing Modulations in Parkinson’s Leukocytes Identified by RNA Sequencing

Plos computational biology, 10(3):e1003517 (2014)

Soreq, L., Salomonis, N., Bronstein, M., Greenberg, D.S., Israel, Z. Bergman, H. and Soreq, H.

Small RNA sequencing-microarray analyses in Parkinson leukocytes reveal deep brain stimulation-induced splicing changes that classify brain region transcriptomes

Frontiers in Molecular Neuroscience, 6, article 10, 20 pp (2013)

Engelhard B, Ozeri N, Israel Z, Bergman H, Vaadia E.

Inducing Gamma Oscillations and Precise Spike Synchrony by Operant Conditioning via Brain-Machine Interface

Neuron; 77(2):361-75 (2013)

Adler A, Finkes I, Katabi S, Prut Y, Bergman H

Encoding by Synchronization in the Primate Striatum

Journal of Neuroscience, 33 (11) 4854-4866 (2013)

Adler A, Katabi S, Finkes I, Prut Y, Bergman H

Different correlation patterns of cholinergic and GABAergic interneurons with striatal projection neurons

Frontiers in Systems Neuroscience, 7:47 (2013)

Soreq, L., Bergman, H., Israel, Z. and Soreq, H.

Deep brain stimulation modulates nonsense-mediated RNA decay in Parkinson’s patients leukocytes

BMC Genomics, 14:478 (2013)

Adler A, Katabi S, Finkes I, Israel Z, Prut Y, Bergman H.

Temporal convergence of dynamic cell assemblies in the striato-pallidal network

Journal of Neuroscience, 32 (7) 2473-2484; (2012)

R.R. Shamir, A. Zaidel, L. Joskowicz, H. Bergan, Z. Israel

Microelectrode Recording Duration and Spatial Density Constraints for Automatic Targeting of the Subthalamic Nucleus

Stereotactic and Functional Neurosurgery 90(5):325-335 (2012)

Soreq, L., Ben-Shaul, Y., Israel, Z., Bergman, H. and Soreq, H.

Meta-analysis of genetic and environmental Parkinson’s disease models reveals a common role of mitochondrial protection pathways

Neurobiology of Disease, Volume 45, Issue 3, Pages 1018-1030 (2012)

Soreq, L., Greenberg, D.S., Bergman, H., Israel, Z. and Soreq, H.

Exon Arrays Reveal Alternative Splicing Aberrations in Parkinson’s Disease Leukocytes

Neurodegenerative Disease 10, 203-206 (2012)

Soreq, L., Israel, Z., Greenberg, D.S., Bergman, H. and Soreq, H.

Deep brain stimulation induces rapidly reversible transcript changes in Parkinson’s leucocytes

Journal of cellular and molecular medicine 16, 1496-1507 (2012)

BenMoyal-Segal, L., Soreq, L., Ben-Shaul, Y., Ben-Ari, S., Ben-Moshe, T., Aviel, S., Bergman, H. and Soreq, H.

Adaptive Alternative Splicing Correlates with Less Environmental Risk of Parkinsonism

Neurodegenerative Disease 9, 87-98 (2012)

Rosin B, Slovik M, Mitelman R, Rivlin-Etzion M, Haber SN, Israel Z, Vaadia E, Bergman H.

Closed-loop deep brain stimulation is superior in ameliorating Parkinsonism

Neuron, 72(2), 370-384 (2011)

Zaidel A, Spivak A, Grieb B, Bergman H, Israel Z.

Subthalamic span of beta-oscillations predicts deep brain stimulation efficacy for Parkinson’s patients

Brain. 133(Pt 7):2007-21 (2010)

Joshua, M. Adler, A. and Bergman, H.

Novelty encoding by the output neurons of the basal ganglia

Frontiers in Systems Neuroscience 8;3:2 (2010)

Adler, A, Joshua M, Rivlin-Etzion M, Mitelman R, Marmor O, Prut Y, Bergman H.

Neurons in both pallidal segments change their firing properties similarly prior to closure of the eyes.

Journal of neurophysiology. 103(1):346-59 (2010)

Joshua, M, Adler, A. and Bergman, H.

The dynamics of dopamine in control of motor behavior

Current Opinion in Neurobiology, Volume 19, Issue 6, Pages 615-620 (2009)

Joshua M, Adler A, Prut Y, Vaadia E, Wickens JR, Bergman H.

Synchronization of midbrain dopaminergic neurons is enhanced by rewarding events

Neuron. 62(5):695-704 (2009)

Joshua, M, Adler A, Rosin B, Vaadia E, Bergman H.

Encoding of probabilistic rewarding and aversive events by pallidal and nigral neurons.

Journal of neurophysiology, Volume 101, Issue 2, Pages 758-772 (2009)

Mitelman, R, Joshua M, Adler A, Bergman H.

A noninvasive, fast and inexpensive tool for the detection of eye open/closed state in primates

Journal of Neuroscience Methods, Volume 178, Issue 2, Pages 350-356 (2009)

Joshua, M, Adler A, Mitelman R, Vaadia E, Bergman H.

Midbrain dopaminergic neurons and striatal cholinergic interneurons encode the difference between reward and aversive events at different epochs of probabilistic classical conditioning trials.

Journal of Neuroscience, 28 (45) 11673-11684 (2008)

Rivlin-Etzion M, Marmor O, Saban G, Rosin B, Haber SN, Vaadia E, Prut Y, Bergman H.

Low-pass filter properties of basal ganglia cortical muscle loops in the normal and MPTP primate model of parkinsonism

J Neurosci. 2008 Jan 16;28(3):633-49. (2008)

Lilach Soreq, Adi Gilboa-Geffen, Sonia Berrih-Aknin, Paul Lacoste, Ariel Darvasi, Eyal Soreq, Hagai Bergman, and Hermona Soreq

Identifying alternative hyper-splicing signatures in MG-thymoma by exon arrays

PLoS One. 2008; 3(6): e2392. (2008)

Parush N, Arkadir D, Nevet A, Morris G, Tishby N, Nelken I, Bergman H.

Encoding by response duration in the basal ganglia

J Neurophysiol. 2008 Dec;100(6):3244-52. (2008)

Neta Zach, Dorrit Inbar, Yael Grinvald, Hagai Bergman and Eilon Vaadia

Emergence of novel representations in primary motor cortex and premotor neurons during associative learning

Journal of Neuroscience 17 September 2008, 28 (38) 9545-9556; (2008)

Soreq L, Israel Z, Bergman H, Soreq H.

Advanced microarray analysis highlights modified neuro-immune signaling in nucleated blood cells from Parkinson’s disease patients

J Neuroimmunol. 2008 Sep 15;201-202:227-36. (2008)

Elias, S, Joshua M, Goldberg JA, Heimer G, Arkadir D, Morris G, Bergman H.

Statistical properties of pauses of the high-frequency discharge neurons in the external segment of the globus pallidus.

Journal of Neuroscience, 27 (10) 2525-2538 (2007)

Joshua, M, Elias S, Levine O, Bergman H.

Quantifying the isolation quality of extracellularly recorded action potentials.

Journal of Neuroscience Methods, Volume 163, Issue 2, Pages 267-282 (2007)

Morris, Nevet, Arkadir, Vaadia and Bergman

Midbrain dopamine neurons encode decisions for future action

Nature Neuroscience volume 9, pages 1057–1063 (2006)

Ben-Shaul Y, Benmoyal-Segal L, Ben-Ari S, Bergman H, Soreq H.

Adaptive acetylcholinesterase splicing patterns attenuate 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinsonism in mice

Eur J Neurosci. 2006 Jun;23(11):2915-22. (2006)

Ben-Shaul Y, Bergman H, Soreq H.

Identifying subtle interrelated changes in functional gene categories using continuous measures of gene expression

Bioinformatics. 2005 Apr 1;21(7):1129-37. Epub 2004 Nov 18. (2005)

Rony Paz, Chen Natan, Thomas Boraud, Hagai Bergman and Eilon Vaadia

Emerging patterns of neuronal responses in supplementary and primary motor areas during sensorimotor adaptation

Journal of Neuroscience 23 November 2005, 25 (47) 10941-10951; (2005)

Paz R, Nathan C, Boraud T, Bergman H, Vaadia E.

Acquisition and generalization of visuomotor transformations by nonhuman primates

Exp Brain Res. 2005 Feb;161(2):209-19. (2005)

Goldberg JA, Rokni U, Boraud T, Vaadia E, Bergman H.

Spike synchronization in the cortex/basal-ganglia networks of Parkinsonian primates reflects global dynamics of the local field potentials

J Neurosci. 2004 Jun 30;24(26):6003-10. (2004)

Arkadir D, Morris G, Vaadia E, Bergman H.

Independent coding of movement direction and reward prediction by single pallidal neurons

J Neurosci. 2004 Nov 10;24(45):10047-56. (2004)

Bar-Gad I, Elias S, Vaadia E, Bergman H.

Complex locking rather than complete cessation of neuronal activity in the globus pallidus of a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated primate in response to pallidal microstimulation

J Neurosci. 2004 Aug 18;24(33):7410-9. (2004)

Morris G, Arkadir D, Nevet A, Vaadia E, Bergman H.

Coincident but distinct messages of midbrain dopamine and striatal tonically active neurons

Neuron. 43(1):133-43. (2004)

Paz R, Boraud T, Natan C, Bergman H, Vaadia E.

Preparatory activity in motor cortex reflects learning of local visuomotor skills

Nat Neurosci. 2003 Aug;6(8):882-90. (2003)

Bar-Gad I, Morris G, Bergman H.

Information processing, dimensionality reduction and reinforcement learning in the basal ganglia

Prog Neurobiol. 71(6):439-73. (2003)

Bar-Gad I, Heimer G, Ritov Y, Bergman H.

Functional correlations between neighboring neurons in the primate Globus Pallidus are weak or nonexistent

J Neurosci. 23(10):4012-6. (2003)

A. Gribova, O. Donchin, H. Bergman, E. Vaadia, S. Cardoso de Oliveira

Timing of bimanual movements in human and non-human primates in relation to neuronal activity in primary motor cortex and supplementary motor area

Experimental Brain Research October 2002, Volume 146, Issue 3, pp 322–335 (2002)

Donchin O, Gribova A, Steinberg O, Mitz AR, Bergman H, Vaadia E.

Single-unit activity related to bimanual arm movements in the primary and supplementary motor cortices

J Neurophysiol. 2002 Dec;88(6):3498-517. (2002)

Steinberg O, Donchin O, Gribova A, Cardosa de Oliveira S, Bergman H, Vaadia E.

Neuronal populations in primary motor cortex encode bimanual arm movements

Eur J Neurosci. 2002 Apr;15(8):1371-80. (2002)

Goldberg JA, Boraud T, Maraton S, Haber SN, Vaadia E, Bergman H.

Enhanced synchrony among primary motor cortex neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine primate model of Parkinson’s disease

J Neurosci. 2002 Jun 1;22(11):4639-53. (2002)

Cardoso de Oliveira S, Gribova A, Donchin O, Bergman H, Vaadia E.

Neural interactions between motor cortical hemispheres during bimanual and unimanual arm movements

Eur J Neurosci. 2001 Dec;14(11):1881-96. (2001)

O. Donchin, A. Gribova, O. Steinberg, H. Bergman, Cardoso S. de Oliveira, E. Vaadia

Local field potentials related to bimanual movements in the primary and supplementary motor cortices

Experimental Brain Research 140(1):46-55 (2001)

Bar-Gad I, Ritov Y, Vaadia E, Bergman H.

Failure in identification of overlapping spikes from multiple neuron activity causes artificial correlations

J Neurosci Methods. 2001 May 30;107(1-2):1-13. (2001)

Raz A, Frechter-Mazar V, Feingold A, Abeles M, Vaadia E, Bergman H.

Activity of pallidal and striatal tonically active neurons is correlated in mptp-treated monkeys but not in normal monkeys

J Neurosci. 2001 Feb 1;21(3):RC128. (2001)

Raz A, Vaadia E, Bergman H.

Firing patterns and correlations of spontaneous discharge of pallidal neurons in the normal and tremulous MPTP Vervet model of Parkinsonism

J Neurosci. 20(22):8559-71. (2000)

Slovin H, Abeles M, Vaadia E, Haalman I, Prut Y, Bergman H.

Frontal cognitive impairments and saccadic deficits in low-dose MPTP-treated monkeys

J Neurophysiol. 1999 Feb;81(2):858-74. (1999)

Bergman H, Raz A, Feingold A, Nini A, Nelken I, Hansel D, Ben-Pazi H, Reches A.

Physiology of MPTP tremor

Mov Disord. 1998;13 Suppl 3:29-34. (1998)

Bergman H, Feingold A, Nini A, Raz A, Slovin H, Abeles M, Vaadia E.

Physiological aspects of information processing in the basal ganglia of normal and parkinsonian primates

Trends Neurosci. 1998 Jan;21(1):32-8. (1998)

Prut Y, Vaadia E, Bergman H, Haalman I, Slovin H, Abeles M.

Spatiotemporal structure of cortical activity: properties and behavioral relevance

J Neurophysiol. 1998 Jun;79(6):2857-74. (1998)

Raz A, Feingold A, Zelanskaya V, Vaadia E, Bergman H.

Neuronal synchronization of tonically active neurons in the striatum of normal and Parkinsonian primates

J Neurophysiol; 76(3):2083-8. (1996J Neurophysiol; 76(3):2083-8.)

Seidemann E, Meilijson I, Abeles M, Bergman H, Vaadia E.

Simultaneously recorded single units in the frontal cortex go through sequences of discrete and stable states in monkeys performing a delayed localization task

J Neurosci. 1996 Jan 15;16(2):752-68. (1996)

Nini A, Feingold A, Slovin H, Bergman H.

Neurons in the globus pallidus do not show correlated activity in the normal monkey, but phase-locked oscillations appear in the MPTP model of Parkinsonism

J Neurophysiol; 74(4):1800-5. (1995)

Vaadia E, Haalman I, Abeles M, Bergman H, Prut Y, Slovin H, Aertsen A.

Dynamics of neuronal interactions in monkey cortex in relation to behavioural events

Nature. 1995 Feb 9;373(6514):515-8. (1995)

Abeles M, Bergman H, Gat I, Meilijson I, Seidemann E, Tishby N, Vaadia E.

Cortical activity flips among quasi-stationary states

Proc Natl Acad Sci U S A. 1995 Sep 12;92(19):8616-20. (1995)

Bergman H, Wichmann T, Karmon B, DeLong MR.

The primate subthalamic nucleus. II. Neuronal activity in the MPTP model of parkinsonism

J. of Neurophysiology. 72: 507-520 (1994)

Abeles M, Prut Y, Bergman H, Vaadia E.

Synchronization in neuronal transmission and its importance for information processing

Prog Brain Res. 1994;102:395-404. (1994)

Ahissar M, Ahissar E, Bergman H, Vaadia E.

Encoding of sound-source location and movement: activity of single neurons and interactions between adjacent neurons in the monkey auditory cortex

J Neurophysiol. 1992 Jan;67(1):203-15. (1992)

Ahissar E, Vaadia E, Ahissar M, Bergman H, Arieli A, Abeles M.

Dependence of cortical plasticity on correlated activity of single neurons and on behavioral context

Science. 1992 Sep 4;257(5075):1412-5. (1992)

Aertsen A, Vaadia E, Abeles M, Ahissar E, Bergman H, Karmon B, Lavner Y, Margalit E, Nelken I, Rotter S.

Neural interactions in the frontal cortex of a behaving monkey: signs of dependence on stimulus context and behavioral state

J Hirnforsch. 1991;32(6):735-43. (1991)

H Bergman, T Wichmann, MR DeLong

Reversal of experimental parkinsonism by lesions of the subthalamic nucleus

Science, Vol. 249, Issue 4975, pp. 1436-1438 (1990)

Vaadia E, Bergman H, Abeles M.

Neuronal activities related to higher brain functions–theoretical and experimental implications

IEEE Trans Biomed Eng. 1989 Jan;36(1):25-35. (1989)

Open Positions

At this time there are no available positions in the lab.

Additional Information

Hagai Bergman

Professor

Email: hagaibe@ekmd.huji.ac.il

Phone: +972-2-6757388

Fax: +972-2-6439736

Hagai Bergman

@hb_cell

https://basalganglia.huji.ac.il