Aviv Mezer Lab

ELSC Members

Human Brain Biophysics lab
The Belgian Friends Laboratory for the study of Neurodegenerative Diseases

Research in the lab is focused on in-vivo mapping of human brain structures. We are investigating the relationship between structure, function. Our main research tool is in in-vivo quantitative magnetic resonance imaging – qMRI. We are developing tools to biophysically explain the brain’s MRI signals at different levels and resolutions: from molecular local sources through the cellular organization to the mapping of networks across the entire brain. Using these tools, we are studying brain normal development and aging, as well as characterizing neurological disorders. Our research group’s ultimate goal is to develop an understanding of how individual-specific biological structures influence human cognition, under both normal and pathological conditions.

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Aviv Mezer

Professor

Email: aviv.mezer@elsc.huji.ac.il
Phone: +972-2-6584617
@AvivMezer
Address: The Edmond and Lily Safra Center for Brain Sciences
The Suzanne and Charles Goodman Brain Sciences Building,
Level 2, Room 2202, Edmond J. Safra Campus,
The Hebrew University of Jerusalem, 9190401
Human Brain Biophysics lab
The Belgian Friends Laboratory for the study of Neurodegenerative Diseases

Research in the lab is focused on in-vivo mapping of human brain structures. We are investigating the relationship between structure, function. Our main research tool is in in-vivo quantitative magnetic resonance imaging – qMRI. We are developing tools to biophysically explain the brain’s MRI signals at different levels and resolutions: from molecular local sources through the cellular organization to the mapping of networks across the entire brain. Using these tools, we are studying brain normal development and aging, as well as characterizing neurological disorders. Our research group’s ultimate goal is to develop an understanding of how individual-specific biological structures influence human cognition, under both normal and pathological conditions.

David photo website 2025
David Beniaguev
Post Doc
adi
Adi Kaduri Amichai
PhD Student
Amir_website
Amir Dudai
PhD Student
Ben
Benjamin Weiner
PhD Student
Shiran (2)
Shiran Michael
PhD Student
stav
Stav Hertz
PhD Student
PASS
Vitaly Lerner
PhD Student
Yair
Yair Deitcher
PhD Student
neta
Neta Zylbermann
Lab Manager
Hertz S, Weiner B, Perets N, London M.

Temporal structure of mouse courtship vocalizations facilitates syllable labeling

Commun Biol. (2020)

Dudai A, Yayon N, Soreq H, London M.

Cortical VIP+ /ChAT+ interneurons: from genetics to function

J Neurochem (2020)

Dudai D., Yayon N., Lerner V., Tasaka G., Deitcher Y., Niederhoffe N., Mizrahi A., Soreq H., London M.

Functional characterization of cortical ChAT/VIP interneurons and their effect on the circuit in vivo.

PLoS Biology (2020)

Dudai A, Yayon N, Lerner V, Tasaka Gi, Deitcher Y, et al.

Barrel cortex VIP/ChAT interneurons suppress sensory responses in vivo

PLoS Biology (2020)

Amir Dudai, Michael Doron, Idan Segev and Michael London

Synaptic input and ACh modulation regulate dendritic Ca2+ spike duration in pyramidal neurons, directly affecting their somatic output

Journal of Neuroscience, JN-RM-1470-21 (2021)

David Beniaguev, Idan Segev, Michael London

Single cortical neurons as deep artificial neural networks

Neuron, ISSN 0896-6273 (2021)

Eyal Gal, Rodrigo Perin, Henry Markram, Michael London, Idan Segev

Neuron Geometry Underlies a Universal Local Architecture in Neuronal Networks

bioRxiv preprint first posted online May. 31, 2019 (2019)

David Beniaguev, Idan Segev, Michael London

Single Cortical Neurons as Deep Artificial Neural Networks

bioRxiv preprint first posted online Apr. 18, 2019; (2019)

Christina Labarrera, Yair Deitcher, Amir Dudai, Benjamin Weiner, Adi Kaduri Amichai, Neta Zylbermann, Michael London

Adrenergic Modulation Regulates the Dendritic Excitability of Layer 5 Pyramidal Neurons In Vivo

Cell reports 23 (4), 1034-1044 (2018)

Adar Adamsky*, Adi Kol*, Tirzah Kreisel, Adi Doron, Nofar Ozeri-Engelhard, Talia Melcer, Ron Refaeli, Henrike Horn, Limor Regev, Maya Groysman, Michael London, Inbal Goshen

Astrocytic activation generates de-novo neuronal potentiation and memory enhancement

Cell, Volume 174, Issue 1, 28 June 2018, Pages 59-71 (2018)

N Yayon, A Dudai, N Vrieler, O Amsalem, M London, H Soreq

Intensify3D: Normalizing signal intensity in large heterogenic image stacks

Scientific Reports, volume 8, Article number: 4311 (2018)

N Perets, S Hertz, M London, D Offen

Intranasal administration of exosomes derived from mesenchymal stem cells ameliorates autistic-like behaviors of BTBR mice

Molecular autism 9 (1), 57 (2018)

D Offen, N Perets, S Hertz, M London

Intranasal administration of exosomes derived from mesenchymal stem cells improves autistic-like behaviors of BTBR mice

Cytotherapy 20 (5), S23 (2018)

Z Zalevsky, M London, E Cohen, A Shemer, D Malka

Multi optically-coupled channels module and related methods of computation

US Patent App. 15/755,138 (2018)

Perets N, Segal-Gavish H, Gothelf Y, Barzilay R, Barhum Y, Abramov N, Hertz S, Morozov D, London M, Offen D

Long term beneficial effect of neurotrophic factors-secreting mesenchymal stem cells transplantation in the BTBR mouse model of autism

Behavioural Brain Research Volume 331, Pages 254-260 (2017)

Eyal Gal, Michael London, Amir Globerson, Srikanth Ramaswamy, Michael W Reimann, Eilif Muller, Henry Markram & Idan Segev

Rich cell-type-specific network topology in neocortical microcircuitry

Nature Neuroscience, VOLUME 20 | NUMBER 7 | JULY 2017 (2017)

Cohen E, Malka D, Shemer A, Zalevsky Z and London M

Neural networks within multi-core optic fibers

Scientific Reports volume 6, Article number: 29080 (2016)

Weiner B, Hertz S, Perets N, London M

Social Ultrasonic Vocalization in Awake Head-Restrained Mouse

Frontiers in Behavioral Neuroscience, 10:236 (2016)

London M, Segev I.

synaptic music in dendrites

Nat Neurosci. 2004 Sep;7(9):904-5. (2004)

London M, Segev I.

Synaptic scaling in vitro and in vivo

Nat Neurosci. 2001 Sep;4(9):853-5. (2002)

London M, Schreibman A, Häusser M, Larkum ME, Segev I.

The information efficacy of a synapse

Nat Neurosci. 2002 Apr;5(4):332-40. (2002)

Steinmetz PN, Manwani A, Koch C, London M, Segev I.

Subthreshold voltage noise due to channel fluctuations in active neuronal membranes

J Comput Neurosci. 2000 Sep-Oct;9(2):133-48. (2000)

Segev I, London M.

Untangling dendrites with quantitative models

Science. 2000 Oct 27;290(5492):744-50 (2000)

Michael London, Claude Meunier and Idan Segev

Signal transfer in passive dendrites with non-uniform membrane conductance

Journal of Neuroscience 1 October 1999, 19 (19) 8219-8233 (1999)

At this time there are no available positions in the lab.
Website:
Lab Website
ELSC Program in Theoretical Neuroscience
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Michael London

Associate Professor

Email: mickey.london@mail.huji.ac.il
Phone: +972-2-6586337
Michael London CV
@mikilon
Address: The Edmond and Lily Safra Center for Brain Sciences
The Suzanne and Charles Goodman Brain Sciences Building,
Level 1, Room 2103, Edmond J. Safra Campus,
The Hebrew University of Jerusalem, 9190401
https://www.mikilon.org
לחצו למעבר להרשמה

“Working memory”

New exhibition titled “Working memory” by the artist Alon kedem and in collaboration with ELSC Prof. Leon Deouell. In the picture: Moshe Lion, the mayor of Jerusalem and Prof. Asher Cohen, the president of The Hebrew University of Jerusalem.