We are excited to announce a groundbreaking study led by Prof. Hermona Soreq, alongside Dana Shulman and Prof. Yonatan Loewenstein, that sheds light on the reason why women experience more severe and rapid dementia in Alzheimer’s disease compared to men.

For a long time, it has been recognized that women suffer from more pronounced dementia than men, but the underlying causes have remained elusive. However, according to the researchers, this discrepancy does not stem from structural changes in the brain but rather from cognitive impairments and accelerated dementia, along with the loss of cholinergic neurons, in women with Alzheimer’s.

This remarkable discovery not only marks a crucial milestone in our understanding of the disease but also paves the way for the development of targeted medications specifically tailored to women affected by Alzheimer’s. By unraveling a molecular mechanism occurring in the brains of female Alzheimer’s patients, we are now one step closer to providing more effective treatments for those who need it most.

The full study is available here.