How did the brain evolve to enhance its own capabilities? Where exactly did these changes take place in its structure and function? In my research, I explore these questions by investigating the evolution of brain function at the single-neuron level. How did neurons’ morphology and electrical properties adapt over time to support more complex functional abilities? To answer this, I create detailed compartmental models of human, mouse, and rat neurons and analyze changes in their electrical and computational properties. I also introduce a new analytical framework to examine how alterations in neuronal morphology affect their computational functions, helping to deepen our understanding of the neural changes that underpin these functional enhancements.