Idan Segev Lab

ELSC Members

David and Inez Myers Chair in Neural Computation, Emeritus
The lab for understanding neurons Drahi Brain Computation & Communication Laboratory

Neurons – these aesthetic elementary microchips of the brain and their synapses change as they receive and transmit information. This enables us to learn and adapt to the complicated environment around us, have new ideas and create new “brain inspired” learning machines, Art and Science. A deep understanding of a computing and learning system such as our own brain requires understanding the computational and plastic functions of its basic components – the nerve cells, their synapses and the specific neuronal networks that they form. Our laboratory utilizes detailed computer simulations of detailed cortical circuits (as part of the Blue Brain Project), big data and machine learning approaches, and analytic methods to study the relationships between neurons’ geometry, network connectivity/plasticity and network dynamics. A recent challenge at the lab. is to understand the unique properties of Human cortical neurons and cortical circuits, measured in fresh human tissue obtained following brain operations, and in close collaboration with several international groups (under the “Cell Census” NIH BRAIN Initiative).

Idan Segev

Professor Emeritus

Phone: +972-54-8820610
Address: The Edmond and Lily Safra Center for Brain Sciences
The Suzanne and Charles Goodman Brain Sciences Building,
Level 2, Room 1202, Edmond J. Safra Campus,
The Hebrew University of Jerusalem, 9190401
David and Inez Myers Chair in Neural Computation, Emeritus
The lab for understanding neurons Drahi Brain Computation & Communication Laboratory

Neurons – these aesthetic elementary microchips of the brain and their synapses change as they receive and transmit information. This enables us to learn and adapt to the complicated environment around us, have new ideas and create new “brain inspired” learning machines, Art and Science. A deep understanding of a computing and learning system such as our own brain requires understanding the computational and plastic functions of its basic components – the nerve cells, their synapses and the specific neuronal networks that they form. Our laboratory utilizes detailed computer simulations of detailed cortical circuits (as part of the Blue Brain Project), big data and machine learning approaches, and analytic methods to study the relationships between neurons’ geometry, network connectivity/plasticity and network dynamics. A recent challenge at the lab. is to understand the unique properties of Human cortical neurons and cortical circuits, measured in fresh human tissue obtained following brain operations, and in close collaboration with several international groups (under the “Cell Census” NIH BRAIN Initiative).

david
David Beniaguev
PhD Student
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Eilam Goldenberg Leleo
PhD Student
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Eyal Gal
PhD Student
IMG_7232
Hadas Manor
PhD Student
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Toviah Moldwin
PhD Student
ELSC-Seminars-General
Jonathan Leibner
MSc Student
ELSC-Seminars-General
Sima Dubnov
MSc Student
ELSC-Seminars-General
Moria Fridman
MSc Student
ELSC-Seminars-General
Menachem
Kalmanson
MSc Student
David Beniaguev, Idan Segev, Michael London

Neuron, ISSN 0896-6273 (2021)

Yaara Lefler, Oren Amsalem, Nora Vrieler, Idan Segev, Yosef Yarom

eLife (2020)

Amsalem, O., Eyal, G., Rogozinski, N. et al.

Nat Commun 11, 288 (2019)

Eyal Gal, Rodrigo Perin, Henry Markram, Michael London, Idan Segev

bioRxiv preprint first posted online May. 31, 2019 (2019)

David Beniaguev, Idan Segev, Michael London

bioRxiv preprint first posted online Apr. 18, 2019; (2019)

Guy Eyal, Matthijs B. Verhoog, Guilherme Testa-Silva, Yair Deitcher, Ruth Benavides-Piccione, Javier DeFelipe, Christiaan P. J. de Kock, Huibert D. Mansvelder, Idan Sege

doi: 10.3389/fncel.2018.00181 (2018)

Ohad Dan, Elizabeth Hopp, Alexander Borst, Idan Segev

SCIENTIFIC REPORTS | (2018) 8:5787 | DOI:10.1038/s41598-018-23998-9 (2018)

Moldwin T., Segev I.

bioRxiv preprint first posted online Nov. 9, 2018; doi: https://dx.doi.org/10.1101/464826. (2018)

Lefler Y., Amsalem O., Segev I., Yarom Y.

bioRxiv preprint (2018)

Yair Deitcher, Guy Eyal, Lida Kanari, Matthijs B. Verhoog, Guy Antoine Atenekeng Kahou, Huibert D. Mansvelder, Christiaan P.J. de Kock, and Idan Segev

Cerebral Cortex, 2017; 1-17, doi: 10.1093/cercor/bhx226 (2017)

Eyal Gal, Michael London, Amir Globerson, Srikanth Ramaswamy, Michael W Reimann, Eilif Muller, Henry Markram & Idan Segev

Nature Neuroscience, VOLUME 20 | NUMBER 7 | JULY 2017 (2017)

Michael Doron, Giuseppe Chindemi, Eilif Muller, Henry Markram, Idan Segev

Cell Reports 21, 1550-1561 (2017)

Rössert Ch., Pozzorini Ch., Chindemi G., Davison A. P., Eroe C., King J., Newton T. H., Nolte M. Ramaswamy S., Reimann M. W., Gewaltig M. O., Gerstner W. Markram H., Segev I., Muller E.

arXiv:1604.00087 (2016)

DeFelipe J., Douglas R. J., Hill S. L., Lein E. S., Martin K. A. C., Rockland K. S., Segev I., Shepherd G. M., Tamás G.

Frontiers Neuroanat., 10 June 2016 (2016)

Amsalem O., Van Geit W., Muller E., Markram H., Segev I.

Cerebral Cortex 26(8): 3655–3668. (2016)

Van Geit W., Gevaert M., Chindemi G., Rössert Ch., Courcol J. D., Muller E., Schürmann F., Segev I., Markram H.

Frontiers Neuroinform. 2016; 10: 17. (2016)

Guy Eyal, Matthijs B Verhoog, Guilherme Testa-Silva, Yair Deitcher, Johannes C Lodder, Ruth Benavides-Piccione, Juan Morales, Javier DeFelipe, Christiaan PJ de Kock, Huibert D Mansvelder, Idan Segev

eLife 2016;5:e16553. DOI: 10.7554/eLife.16553 (2016)

Etay Hay, Idan Segev,

Cereb Cortex. 25(10):3561-71 (2015)

Markram H et al.

Cell Volume 163, Issue 2, P456-492 (2015)

Idan Segev, Luis M. Martinez and Robert J. Zatorre,

Front. Hum. Neurosci. (2014)

Guy Eyal, Huibert D. Mansvelder, Christiaan P.J. de Kock, and Idan Segev,

Journal of Neuroscience, 34 (24) 8063-8071 (2014)

Jonathan Laudanski, Benjamin Torben-Nielsen, Idan Segev,

PLOS Computational Biology | Volume 10 | Issue 8 | e1003775 (2014)

Segev Idan and Schurmann Felix.

Frontiers for young minds (2013)

Leora Sarid; Dirk Feldmeyer; Albert Gidon; Bert Sakmann; Idan Segev,

Cereb Cortex. 25(4): 849–858. (2013)

Lital Bar-Ilan, Albert Gidon and Idan Segev

Front. Neural Circuits (2013)

Etay Hay, Felix Schurmann, Henry Markram and Idan Segev

J Neurophysiol. 109(12):2972-81 (2013)

Anat Yaron-Jakoubovitch, Christof Koch, Idan Segev, and Yosef Yarom

Front Neural Circuits. 7: 116. (2013)

Druckmann Sh., Hill S., Schurmann F., Markram H., and Segev I.

Cereb Cortex. 23(12):2994-3006. (2012)

Shaul Druckmann, Thomas K. Berger, Felix Schürmann, Sean Hill, Henry Markram, Idan Segev

PLOS Computational Biology 7:e1002133 (2012)

Nowik I, Zamir Sh, Segev I.

Frontiers in Computational Neuroscience, Volume 6, Article 16 (2012)

Gidon A.,Segev I.

Neuron; 75(2):330-41 (2012)

Benjamin Torben-Nielsen , Idan Segev, Yosef Yarom

PLoS Computational Biology, Volume 8 | Issue 7 | e1002580 (2012)

Etay Hay, Sean Hill2, Felix Schurmann, Henry Markram, Idan Segev

PLoS Computational Biology | Volume 7 | Issue 7 | e1002107 (2011)

Bar Ilan L., Gidon A. and Segev I.

J Neurophysiol 105:989-998 (2010)

Gidon A. and Segev I.

J Neurophysiol. 101(6): 3226–3234 (2009)

Yaron-Jakoubovitch A., Jacobson G., Koch Ch., Segev I. and Yarom Y.

Front Cell Neurosci. 13;2:3 (2008)

Druckmann S, Berger TK, Hill S, Schurmann F, Markram H, Segev I.

Biol Cybern. 99(4-5):371-9. (2008)

Rabinowitch I. and Segev I.

Trends Neurosci. 31(8):377-83 (2008)

Druckmann, S., Banitt, Y., Gideon, A., Schurmann, F., Markram, H. and Segev I.

Front Neurosci. 2007 Nov; 1(1): 7–18. (2007)

Sarid, L., Bruno R., Sakmann B., Segev I., and Feldmeyer D.

Proc Natl Acad Sci U S A. 2007 Oct 9;104(41):16353-8. (2007)

Cuntz H, Borst A, Segev I,

Theor Biol Med Model. 2007; 4: 21. (2007)

Cuntz H, Haag J, Forstner F, Segev I, Borst A

Proc Natl Acad Sci U S A. 2007 Jun 12;104(24):10229-33. (2007)

Diba K, Koch C and Segev I.

J Comput Neurosci. 2006 Feb;20(1):77-84. (2006)

Rabinowitch I. and Segev I.

Journal of Neuroscience 27 December 2006, 26 (52) 13474-13484; (2006)

Rabinowitch I. and Segev I.

J Neurophysiol 96:276-283 (2006)

anitt Y, Martin KA, Segev I.

J Neurophysiol. 2005 Jul;94(1):865-70. (2005)

Jacobson GA, Diba K, Yaron-Jakoubovitch A, Oz Y, Koch C, Segev I, Yarom Y

J Physiol. 2005 Apr 1; 564(Pt 1): 145–160. (2005)

Fuhrmann G, Cowan A, Segev I, Tsodyks M, Stricker C.

J Physiol. 2004 Jun 1;557(Pt 2):415-38. (2004)

London M, Segev I.

Nat Neurosci. 2004 Sep;7(9):904-5. (2004)

Vladimir Litvak; Haim Sompolinsky; Idan Segev; Moshe Abeles

J Neurosci. 2003 Apr 1;23(7):3006-15. (2003)

Segev I.

Nat Neurosci. 2003 Jun;6(6):543-4. (2003)

Fuhrmann G., Segev I., Markram H., and Tsodyks M.

J Neurophysiol. 2002 Jan;87(1):140-8 (2002)

Meunier C, Segev I.

Trends Neurosci. 2002 Nov;25(11):558-63. (2002)

Meunier C, Segev I.

Trends Neurosci. 2002 Nov;25(11):558-63 (2002)

London M, Segev I.

Nat Neurosci. 2001 Sep;4(9):853-5. (2002)

London M, Schreibman A, Häusser M, Larkum ME, Segev I.

Nat Neurosci. 2002 Apr;5(4):332-40. (2002)

Schneidmann E., Segev I., and Tishby N.

Advances in neural information processing systems · February 2000 (2000)

Steinmetz PN, Manwani A, Koch C, London M, Segev I.

J Comput Neurosci. 2000 Sep-Oct;9(2):133-48. (2000)

Koch C, Segev I.

Nat Neurosci. 2000 Nov;3 Suppl:1171-7 (2000)

Segev I, London M.

Science. 2000 Oct 27;290(5492):744-50 (2000)

Segev I, Schneidman E.

J Physiol Paris. 1999 Sep-Oct;93(4):263-70 (1999)

Anderson JC, Binzegger T, Kahana O, Martin KA, Segev I.

Nat Neurosci. 1999 Sep;2(9):820-4 (1999)

Michael London, Claude Meunier and Idan Segev

Journal of Neuroscience 1 October 1999, 19 (19) 8219-8233 (1999)

Segev I.

Nat Neurosci. 1999 Dec;2(12):1041-3 (1999)

Schneidman E, Freedman B, Segev I.

Neural Comput. 1998 Oct 1;10(7):1679-703. (1998)

Senn W, Segev I, Tsodyks M.

Neural Comput. 1998 May 15;10(4):815-9. (1998)

Idan Segev

Nature. 1998 May 21;393(6682):207-8. (1998)

Koch C, Rapp M, Segev I.

Cereb Cortex. 1996 Mar-Apr;6(2):93-101 (1996)

Rapp M, Yarom Y, Segev I.

Proc Natl Acad Sci U S A. 1996 Oct 15;93(21):11985-90 (1996)

Yoram Gutfreund, Tamar Flash, Yosef Yarom, Graziano Fiorito, Idan Segev and Binyamin Hochner

Journal of Neuroscience 15 November 1996, 16 (22) 7297-7307 (1996)

Segev I, Friedman A, White EL, Gutnick MJ.

J Comput Neurosci. 1995 Jun;2(2):117-30. (1995)

Gutfreund Y, Yarom Y, Segev I.

J Physiol. 1995 Mar 15;483 ( Pt 3):621-40. (1995)

Zador AM, Agmon-Snir H, Segev I.

J Neurosci. 1995 Mar;15(3 Pt 1):1669-82. (1995)

Rapp M, Segev I, Yarom Y.

J Physiol. 1994 Jan 1;474(1):101-18. (1994)

Agmon-Snir H, Segev I.

J Neurophysiol. 1993 Nov;70(5):2066-85. (1993)

Holmes WR, Segev I, Rall W.

J Neurophysiol. 1992 Oct;68(4):1401-20. (1992)

W. Rall, R. E. Burke, W. R. Holmes, J. J. Jack, S. J. Redman, and I. Segev

Physiol Rev. 1992 Oct;72(4 Suppl):S159-86. (1992)

Idan Segev

Trends In Neuroscience | VOLUME 15, ISSUE 11, P414-421, NOVEMBER 01, 1992 (1992)

Rapp M., Yarom Y., and Segev I.

Neural Computation; Volume: 4 , Issue: 4 , July 1992 (1992)

Manor Y, Koch C, Segev I.

Biophys J. 1991 Dec;60(6):1424-37. (1991)

Y Manor, J Gonczarowski, and I Segev

Biophys J. 1991 Dec; 60(6): 1411–1423. (1991)

Segev I, Fleshman JW Jr, Burke RE.

J Neurophysiol. 1990 Aug;64(2):648-60. (1990)

Nitzan R., Segev I. and Yarom Y.

JOURNAL OF NEUROPHYSIOLOGY Vol. 63. No. 2, February 1990. (1990)

Burke RE, Fleshman JW, Segev I.

J Physiol (Paris). 1988-1989;83(3):133-40. (1989)

Segev I., Rall W.

J Neurophysiol. 1988 Aug;60(2):499-523. (1988)

Fleshman JW, Segev I, Burke RB.

J Neurophysiol. 1988 Jul;60(1):60-85. (1988)

Segev I, Fleshman JW, Miller JP, Bunow B.

Biol Cybern. 1985;53(1):27-40. (1985)

Segev I, Parnas I.

J Gen Physiol. 1985 May;85(5):729-41. (1985)

Shepherd GM, Brayton RK, Miller JP, Segev I, Rinzel J, Rall W.

Proc Natl Acad Sci U S A. 1985 Apr;82(7):2192-5. (1985)

I Parnas and I Segev

J Physiol. 1979 Oct; 295: 323–343. (1979)

At this time there are no available positions in the lab.
Honors:
The David & Inez Myers Chair in Computational Neuroscience

Lab Website:
Lab Website

Idan Segev

Professor Emeritus

Phone: +972-54-8820610
Address: The Edmond and Lily Safra Center for Brain Sciences
The Suzanne and Charles Goodman Brain Sciences Building,
Level 2, Room 1202, Edmond J. Safra Campus,
The Hebrew University of Jerusalem, 9190401

Winners announced for the ELSC photography competition