Our research group use physiological (multiple electrode) tools to explore the computation physiology of the basal ganglia, their disorders and therapy. We record the activity of several neurons in the different basal ganglia nuclei during behavioral tasks and over the wake-sleep cycle. We do it before and after induction of disease-like state (e.g., Parkinson’s disease, schizophrenia) in animal models and in human patients undergoing deep brain stimulation (DBS) procedures. Our goal is to provide better understanding of the physiology and pathophysiology of the basal ganglia, and to use this understanding to develop better methods for treatment (eg closed-loop DBS).
Hagai Bergman Lab
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Simone and Bernard Guttman Chair in Brain Research
The French Friends Parkinson’s Laboratory
Hagai Bergman
Professor
Email: hagaibe@ekmd.huji.ac.il
Phone: +972-2-6757388
Fax: +972-2-6439736
Address: The Edmond and Lily Safra Center for Brain Sciences
The Suzanne and Charles Goodman Brain Sciences Building,
Level 3, Room 1304 Edmond J. Safra Campus,
The Hebrew University of Jerusalem, 9190401
The Suzanne and Charles Goodman Brain Sciences Building,
Level 3, Room 1304 Edmond J. Safra Campus,
The Hebrew University of Jerusalem, 9190401
Simone and Bernard Guttman Chair in Brain Research
The French Friends Parkinson’s Laboratory
Our research group use physiological (multiple electrode) tools to explore the computation physiology of the basal ganglia, their disorders and therapy. We record the activity of several neurons in the different basal ganglia nuclei during behavioral tasks and over the wake-sleep cycle. We do it before and after induction of disease-like state (e.g., Parkinson’s disease, schizophrenia) in animal models and in human patients undergoing deep brain stimulation (DBS) procedures. Our goal is to provide better understanding of the physiology and pathophysiology of the basal ganglia, and to use this understanding to develop better methods for treatment (eg closed-loop DBS).
David Beniaguev, Sapir Shapira, Idan Segev, Michael London
The Journal of neuroscience : the official journal of the Society for Neuroscience (2026)
Bradley C Rauscher, Natalie Fomin-Thunemann, Sreekanth Kura, Patrick R Doran, Pablo D Perez, Kıvılcım Kılıç, Emily A Martin, Dora Balog, Nathan X Chai, Francesca A Froio, Patrick F Bloniasz, Kate E Herrema, Rockwell P Tang, Scott G Knudstrup, Andrew Garcia, John X Jiang, Jeffrey P Gavornik, Michael London, David Kleinfeld, Michael E Hasselmo, Laura D Lewis, Sava Sakadzic, Lei Tian, Gal Mishne, Emily P Stephen, Martin Thunemann, David A Boas, Anna Devor
Nature neuroscience (2026)
Qixin Yang, Shulamit Baror-Sebban, Rotem Kipper, Michael London, Yoav Adam
Neuron (2026)
Hertz S, Weiner B, Perets N, London M.
Commun Biol. (2020)
Dudai A, Yayon N, Soreq H, London M.
J Neurochem (2020)
Dudai D., Yayon N., Lerner V., Tasaka G., Deitcher Y., Niederhoffe N., Mizrahi A., Soreq H., London M.
PLoS Biology (2020)
Dudai A, Yayon N, Lerner V, Tasaka Gi, Deitcher Y, et al.
PLoS Biology (2020)
Amir Dudai, Michael Doron, Idan Segev and Michael London
Journal of Neuroscience, JN-RM-1470-21 (2021)
David Beniaguev, Idan Segev, Michael London
Neuron, ISSN 0896-6273 (2021)
Eyal Gal, Rodrigo Perin, Henry Markram, Michael London, Idan Segev
bioRxiv preprint first posted online May. 31, 2019 (2019)
David Beniaguev, Idan Segev, Michael London
bioRxiv preprint first posted online Apr. 18, 2019; (2019)
Christina Labarrera, Yair Deitcher, Amir Dudai, Benjamin Weiner, Adi Kaduri Amichai, Neta Zylbermann, Michael London
Cell reports 23 (4), 1034-1044 (2018)
Adar Adamsky*, Adi Kol*, Tirzah Kreisel, Adi Doron, Nofar Ozeri-Engelhard, Talia Melcer, Ron Refaeli, Henrike Horn, Limor Regev, Maya Groysman, Michael London, Inbal Goshen
Cell, Volume 174, Issue 1, 28 June 2018, Pages 59-71 (2018)
N Yayon, A Dudai, N Vrieler, O Amsalem, M London, H Soreq
Scientific Reports, volume 8, Article number: 4311 (2018)
N Perets, S Hertz, M London, D Offen
Molecular autism 9 (1), 57 (2018)
D Offen, N Perets, S Hertz, M London
Cytotherapy 20 (5), S23 (2018)
Z Zalevsky, M London, E Cohen, A Shemer, D Malka
US Patent App. 15/755,138 (2018)
Perets N, Segal-Gavish H, Gothelf Y, Barzilay R, Barhum Y, Abramov N, Hertz S, Morozov D, London M, Offen D
Behavioural Brain Research Volume 331, Pages 254-260 (2017)
Eyal Gal, Michael London, Amir Globerson, Srikanth Ramaswamy, Michael W Reimann, Eilif Muller, Henry Markram & Idan Segev
Nature Neuroscience, VOLUME 20 | NUMBER 7 | JULY 2017 (2017)
Cohen E, Malka D, Shemer A, Zalevsky Z and London M
Scientific Reports volume 6, Article number: 29080 (2016)
Weiner B, Hertz S, Perets N, London M
Frontiers in Behavioral Neuroscience, 10:236 (2016)
London M, Schreibman A, Häusser M, Larkum ME, Segev I.
Nat Neurosci. 2002 Apr;5(4):332-40. (2002)
Steinmetz PN, Manwani A, Koch C, London M, Segev I.
J Comput Neurosci. 2000 Sep-Oct;9(2):133-48. (2000)
Segev I, London M.
Science. 2000 Oct 27;290(5492):744-50 (2000)
Michael London, Claude Meunier and Idan Segev
Journal of Neuroscience 1 October 1999, 19 (19) 8219-8233 (1999)
At this time there are no available positions in the lab.
Michael London
Associate Professor
Phone: +972-2-6586337
Address: The Edmond and Lily Safra Center for Brain Sciences
The Suzanne and Charles Goodman Brain Sciences Building,
Level 1, Room 2103, Edmond J. Safra Campus,
The Hebrew University of Jerusalem, 9190401
The Suzanne and Charles Goodman Brain Sciences Building,
Level 1, Room 2103, Edmond J. Safra Campus,
The Hebrew University of Jerusalem, 9190401
