Adi Mizrahi Lab

ELSC Members

Adi Mizrahi

Professor

Phone: +972-2-6585163
Lab Phone: +972-2-6585163
Office Phone: +972-2-6586460
Address: The Edmond and Lily Safra Center for Brain Sciences
The Suzanne and Charles Goodman Brain Sciences Building,
Level 2, Room 1204, Edmond J. Safra Campus,
The Hebrew University of Jerusalem, 9190401
The Eric Roland Chair in Brain Sciences
The NeuroPlasticity lab

Our lab is interested in how the brain we are born with meets the world we grow into. We study the interplay between innate and learned aspects of behavior, asking how experience reshapes neural circuits that support core behaviors such as categorizing stimuli, caring for offspring, and choosing mates. We use the auditory and olfactory systems as our main windows into the brain, because they are tightly linked to ethologically meaningful behaviors – from recognizing a pup’s call to discriminating a predator odor or a potential partner.

A central theme in the lab is development, with a particular focus on adolescence as a transitional period where brain and behavior are not always in sync. We ask how sound and odor categories are formed and refined across development, how parental experience sculpts auditory and olfactory representations, and how social and sexual cues are integrated by cortical circuits. Across these projects, we are especially interested in how “hard-wired” predispositions (for example, to respond to pups, conspecifics or threats) interact with learning to produce flexible, context-dependent behavior.

To address these questions, we combine systems neuroscience and behavior: multi-neuron recordings and imaging in defined circuits, targeted circuit manipulations, and carefully designed behavioral paradigms that probe discrimination, category learning and natural behaviors such as parenting. By following neural activity and behavior over time, we aim to understand how circuits change as animals learn, grow up, and transition between life stages – and how these changes allow the same brain to support both stable instincts and lifelong learning.

David photo website 2025
David Beniaguev
Post Doc
adi
Adi Kaduri Amichai
PhD Student
Amir_website
Amir Dudai
PhD Student
Ben
Benjamin Weiner
PhD Student
Shiran (2)
Shiran Michael
PhD Student
stav
Stav Hertz
PhD Student
PASS
Vitaly Lerner
PhD Student
Yair
Yair Deitcher
PhD Student
neta
Neta Zylbermann
Lab Manager
Hertz S, Weiner B, Perets N, London M.

Commun Biol. (2020)

Dudai A, Yayon N, Soreq H, London M.

J Neurochem (2020)

Dudai D., Yayon N., Lerner V., Tasaka G., Deitcher Y., Niederhoffe N., Mizrahi A., Soreq H., London M.

PLoS Biology (2020)

Dudai A, Yayon N, Lerner V, Tasaka Gi, Deitcher Y, et al.

PLoS Biology (2020)

Amir Dudai, Michael Doron, Idan Segev and Michael London

Journal of Neuroscience, JN-RM-1470-21 (2021)

David Beniaguev, Idan Segev, Michael London

Neuron, ISSN 0896-6273 (2021)

Eyal Gal, Rodrigo Perin, Henry Markram, Michael London, Idan Segev

bioRxiv preprint first posted online May. 31, 2019 (2019)

David Beniaguev, Idan Segev, Michael London

bioRxiv preprint first posted online Apr. 18, 2019; (2019)

Christina Labarrera, Yair Deitcher, Amir Dudai, Benjamin Weiner, Adi Kaduri Amichai, Neta Zylbermann, Michael London

Cell reports 23 (4), 1034-1044 (2018)

Adar Adamsky*, Adi Kol*, Tirzah Kreisel, Adi Doron, Nofar Ozeri-Engelhard, Talia Melcer, Ron Refaeli, Henrike Horn, Limor Regev, Maya Groysman, Michael London, Inbal Goshen

Cell, Volume 174, Issue 1, 28 June 2018, Pages 59-71 (2018)

N Yayon, A Dudai, N Vrieler, O Amsalem, M London, H Soreq

Scientific Reports, volume 8, Article number: 4311 (2018)

Z Zalevsky, M London, E Cohen, A Shemer, D Malka

US Patent App. 15/755,138 (2018)

Perets N, Segal-Gavish H, Gothelf Y, Barzilay R, Barhum Y, Abramov N, Hertz S, Morozov D, London M, Offen D

Behavioural Brain Research Volume 331, Pages 254-260 (2017)

Eyal Gal, Michael London, Amir Globerson, Srikanth Ramaswamy, Michael W Reimann, Eilif Muller, Henry Markram & Idan Segev

Nature Neuroscience, VOLUME 20 | NUMBER 7 | JULY 2017 (2017)

Cohen E, Malka D, Shemer A, Zalevsky Z and London M

Scientific Reports volume 6, Article number: 29080 (2016)

Weiner B, Hertz S, Perets N, London M

Frontiers in Behavioral Neuroscience, 10:236 (2016)

London M, Segev I.

Nat Neurosci. 2004 Sep;7(9):904-5. (2004)

London M, Segev I.

Nat Neurosci. 2001 Sep;4(9):853-5. (2002)

London M, Schreibman A, Häusser M, Larkum ME, Segev I.

Nat Neurosci. 2002 Apr;5(4):332-40. (2002)

Steinmetz PN, Manwani A, Koch C, London M, Segev I.

J Comput Neurosci. 2000 Sep-Oct;9(2):133-48. (2000)

Segev I, London M.

Science. 2000 Oct 27;290(5492):744-50 (2000)

Michael London, Claude Meunier and Idan Segev

Journal of Neuroscience 1 October 1999, 19 (19) 8219-8233 (1999)

At this time there are no available positions in the lab.

Michael London

Associate Professor

Phone: +972-2-6586337
Address: The Edmond and Lily Safra Center for Brain Sciences
The Suzanne and Charles Goodman Brain Sciences Building,
Level 1, Room 2103, Edmond J. Safra Campus,
The Hebrew University of Jerusalem, 9190401

“Working memory”