Paper of the month

April 2021

Nelken’s & Tishby’s Labs | Meshorer’s Lab | Kalcheim’s Lab | Joshua’s Lab

Nelken's & Tishby’s Labs: Value-complexity tradeoff explains mouse navigational learning

Amir N, Suliman-Lavie R, Tal M, Shifman S, Tishby N, Nelken I

PLoS Comput Biol 16(12): e1008497  (2020)

Meshorer's Lab: Pluripotent stem cell-derived models of neurological diseases reveal early transcriptional heterogeneity

Sorek, M., Oweis, W., Nissim-Rafinia, M. et al.

Genome Biol 22, 73 (2021)  (2021)

Kalcheim’s Lab: Notch signaling is a critical initiator of roof plate formation as revealed by the use of RNA profiling of the dorsal neural tube

Shai Ofek, Sophie Wiszniak, Sarah Kagan, Markus Tondl, Quenten Schwarz, Chaya Kalcheim

bioRxiv 2020.12.09.417279 (2020)

Joshua's Lab: Passive Motor Learning: Oculomotor Adaptation in the Absence of Behavioral Errors

Matan Cain, Yehudit Botschko, Mati Joshua

eNeuro 16 February 2021, 8 (2) ENEURO.0232-20.2020 (2021)

March 2021

Soreq’s Lab | Mizrahi’s Lab | Loewenstein’s & Ahissar’s Labs | Prut’s & Joshua’s Labs

Soreq’s Lab: Transfer RNA fragments replace microRNA regulators of the cholinergic poststroke immune blockade

Katarzyna Winek, Sebastian Lobentanzer, Bettina Nadorp, Serafima Dubnov, Claudia Dames, Sandra Jagdmann, Gilli Moshitzky, Benjamin Hotter, Christian Meisel, David S. Greenberg, Sagiv Shifman, Jochen Klein, Shani Shenhar-Tsarfaty, Andreas Meisel, Hermona Soreq

Proceedings of the National Academy of Sciences, 117 (51) 32606-32616 (2020)

Mizrahi’s Lab: Flexible categorization in the mouse olfactory bulb

Elena Kudryavitskaya, Eran Marom, Haran Shani-Narkiss, David Pash, Adi Mizrahi

Current Biology, 2021, ISSN 0960-9822 (2021)

Loewenstein’s & Ahissar’s Labs: Dissecting the Roles of Supervised and Unsupervised Learning in Perceptual Discrimination Judgments

Yonatan Loewenstein, Ofri Raviv, Merav Ahissar

Journal of Neuroscience 27 January 2021, 41 (4) 757-765 (2021)

Prut’s & Joshua’s Labs: Area-specific thalamocortical synchronization underlies the transition from motor planning to execution

Abdulraheem Nashef, Rea Mitelman, Ran Harel, Mati Joshua, Yifat Prut

Proceedings of the National Academy of Sciences, 118 (6) e2012658118 (2021)

December 2020

Yarom’s Lab | Ahissar’s Lab | Tishby’s Lab

Yarom's Lab: Pogz deficiency leads to transcription dysregulation and impaired cerebellar activity underlying autism-like behavior in mice

Suliman-Lavie, R., Title, B., Cohen, Y. et al.

Nat Commun 11, 5836 (2020). (2020)

Ahissar's Lab: Short-term memory capacity and sensitivity to language statistics in dyslexia and among musicians

Eva Kimel, Atalia Hai Weiss, Hilla Jakoby, Luba Daikhin, Merav Ahissar

Neuropsychologia, Volume 149, 2020, 107624, ISSN 0028-3932. (2020)

Tishby’s Lab: Surprise response as a probe for compressed memory state

Levi-Aharoni H, Shriki O, Tishby N

PLOS Computational Biology 16(2): e1007065. (2020)

November 2020

Mezer’s & Citri’s Labs | Mizrahi’s & Sompolinsky’s Labs | Binshtok’s Lab

Mezer's & Citri's Labs: Automatic Segmentation of the Dorsal Claustrum in Humans Using in vivo High-Resolution MRI

Shai Berman, Roey Schurr, Gal Atlan, Ami Citri, Aviv A Mezer

Cerebral Cortex Communications, Volume 1, Issue 1, 2020, tgaa062. (2020)

Mizrahi's & Sompolinsky's Labs: Young adult-born neurons improve odor coding by mitral cells

Shani-Narkiss, H., Vinograd, A., Landau, I.D. Tasaka, G., Yayon, N., Terletsky, S., Groysman, M., Maor, I., Sompolinsky, H., Mizrahi, A.

Nat Commun 11, 5867 (2020). https://doi.org/10.1038/s41467-020-19472-8 (2020)

Binshtok’s Lab: The input-output relation of primary nociceptive neurons is determined by the morphology of the peripheral nociceptive terminals

Omer Barkai, Rachely Butterman, Ben Katz, Shaya Lev, Alexander M. Binshtok

Journal of Neuroscience 2 December 2020, 40 (49) 9346-9363 (2020)

October 2020

Soreq’s Lab | Loewenstein’s Lab | Mezer’s Lab

Soreq’s Lab: Parkinson’s disease CircRNAs Resource reveals a link between circSLC8A1 and oxidative stress

Mor Hanan, Alon Simchovitz, Nadav Yayon, Shani Vaknine, Roni Cohen-Fultheim, Miriam Karmon, Nimrod Madrer, Talia Miriam Rohrlich, Moria Maman , Estelle R.Bennett, David S. Greenberg, Eran Meshorer, Erez Y. Levanon, Hermona Soreq and Sebastian Kadener.

EMBO Mol Med (2020) 12: e11942 (2020)

Soreq’s Lab: Pharmaceutical Implications of Sex-Related RNA Divergence in Psychiatric Disorders

Alon Simchovitz-Gesher, Hermona Soreq

Trends in Pharmacological Sciences, Volume 41, Issue 11, 2020, Pages 840-850, ISSN 0165-6147, (2020)

Loewenstein’s Lab: Exploration: from machines to humans

Lior Fox, Ohad Dan, Lotem Elber-Dorozko, Yonatan Loewenstein

Current Opinion in Behavioral Sciences, Volume 35, 2020, Pages 104-111, ISSN 2352-1546, (2020)

Mezer’s Lab: A Comparison of Quantitative R1 and Cortical Thickness in Identifying Age, Lifespan Dynamics, and Disease States of the Human Cortex

A Erramuzpe, R Schurr, J D Yeatman, I H Gotlib, M D Sacchet, K E Travis, H M Feldman, A A Mezer

Cerebral Cortex, Volume 31, Issue 2, February 2021, Pages 1211–1226. (2020)

September 2020

Burak’s Lab | Nelken’s Lab | Goshen’s Lab | Loewenstein’s Lab

Burak's Lab: A theory of joint attractor dynamics in the hippocampus and the entorhinal cortex accounts for artificial remapping and grid cell field-to-field variability

Haggai Agmon, Yoram Burak

eLife 2020;9:e56894 (2020)

Nelken's Lab: Synaptic Recruitment Enhances Gap Termination Responses in Auditory Cortex

Bshara Awwad, Maciej M Jankowski, Israel Nelken

Cerebral Cortex, Volume 30, Issue 8, August 2020, Pages 4465–4480 (2020)

Goshen's Lab: Astrocytes contribute to remote memory formation by modulating hippocampal–cortical communication during learning

Adi Kol, Adar Adamsky, Maya Groysman, Tirzah Kreisel, Michael London & Inbal Goshen

Nat Neurosci 23, 1229–1239 (2020). (2020)

Loewenstein's Lab: Hierarchical cortical gradients in somatosensory processing

Noam Saadon-Grosman, ShaharArzy, Yonatan Loewenstein

NeuroImage, Volume 222, 2020, 117257, ISSN 1053-8119, (2020)

August 2020

Citri’s Lab | Mizrahi’s Lab | Soreq’s Lab | Habib’s Lab

Citri's Lab: Claustral neurons projecting to frontal cortex mediate contextual association of reward

Anna Terem, Ben Jerry Gonzales, Noa Peretz-Rivlin, Reut Ashwal-Fluss, Noa Bleistein, Maria del Mar Reus-Garcia, Diptendu Mukherjee, Maya Groysman, Ami Citri

Current Biology,2020, ISSN 0960-9822 (2020)

Mizrahi's Lab: Learning-related population dynamics in the auditory thalamus

Ariel Gilad, Ido Maor, Adi Mizrahi

eLife 2020;9:e56307 (2020)

Soreq's Lab: A Parkinson's disease CircRNAs Resource reveals a link between circSLC8A1 and oxidative stress

Mor Hanan, Alon Simchovitz, Nadav Yayon, Shani Vaknine, Roni Cohen‐Fultheim, Miriam Karmon, Nimrod Madrer, Talia Miriam, Rohrlich Moria Maman, Estelle R Bennett, David S Greenberg, Eran Meshorer, Erez Y Levanon, Hermona Soreq, Sebastian Kadener

EMBO Mol Med (2020)e11942 (2020)

Habib's Lab: Disease-associated astrocytes in Alzheimer’s disease and aging

Habib, N., McCabe, C., Medina, S. et al.

Nat Neurosci 23, 701–706 (2020)

June 2020

Binshtok’s Lab | Mizrahi’s Lab | Bergman’s Lab | Kalcheim’s Lab

Binshtok's Lab: Abnormal Reinnervation of Denervated Areas Following Nerve Injury Facilitates Neuropathic Pain

Leibovich H, Buzaglo N, Tsuriel S, et al.

Cells. 2020;9(4):1007; (2020)

Mizrahi's Lab: The temporal association cortex is involved in auditory driven maternal plasticity

Gen-ichi Tasaka, Libi Feigin, Ido Maor, Maya Groysman, Laura A. DeNardo, Jennifer K. Schiavo, Robert C. Froemke, Liqun Luo, Adi Mizrahi

Neuron 2020, ISSN 0896-6273 (2020)

Bergman's Lab: Dissociable roles of ventral pallidum neurons in the basal ganglia reinforcement learning network

Alexander Kaplan, Aviv D. Mizrahi-Kliger, Zvi Israel, Avital Adler & Hagai Bergman

Nat Neurosci 23, 556–564 (2020). (2020)

Kalcheim's Lab: Neural tube development depends on notochord-derived Sonic hedgehog released into the sclerotome

Nitza Kahane and Chaya Kalcheim

Development 2020 147: dev183996 (2020)

April 2020

Segev’s Lab | Meshorer’s Lab | Grodzinsky’s Lab | Vaadia’s Lab

Segev's Lab: Neuron_Reduce - a brand new tool to simplify complex neuron models

Amsalem, O., Eyal, G., Rogozinski, N. et al.

Nat Commun 11, 288 (2020)

Meshorer's Lab: Predicted Archaic 3D Genome Organization Reveals Genes Related to Head and Spinal Cord Separating Modern from Archaic Humans

Daniel Batyrev, Elisheva Lapid, Liran Carmel & Eran Meshorer

Cells 2020, 9(1), 48; (2020)

Grodzinsky's Lab: Logical negation mapped onto the brain

Grodzinsky, Y., Deschamps, I., Pieperhoff, P. et al.

Brain Struct Funct 225, 19–31 (2020)

Vaadia's Lab: Phase-Specific Microstimulation Differentially Modulates Beta Oscillations and Affects Behavior

Oren Peles, Uri Werner-Reiss, Hagai Bergman, Zvi Israel, Eilon Vaadia

Cell Reports, Volume 30, Issue 8, 2020 (2020)

March 2020

Segev’s & Yarom’s Labs | Joshua’s Lab | London’s Lab | Soreq’s Lab

Segev's & Yarom's Labs: Using subthreshold events to characterize the functional architecture of the electrically coupled inferior olive network

Yaara Lefler, Oren Amsalem, Nora Vrieler, Idan Segev, Yosef Yarom

Elife. 2020 Feb 11;9:e43560. (2020)

Joshua's Lab: Encoding of eye movements explains reward-related activity in cerebellar simple spikes

Adi Lixenberg, Merav Yarkoni, Yehudit Botschko and Mati Joshua

Journal of Neurophysiology 2020 123:2, 786-799  (2020)

London's Lab: Barrel cortex VIP/ChAT interneurons suppress sensory responses in vivo

Amir Dudai, Nadav Yayon, Vitaly Lerner, Gen-ichi Tasaka, Yair Deitcher, Karin Gorfine, Naomi Niederhoffer, Adi Mizrahi, Hermona Soreq, Michael London

PLOS Biology 18(2): e3000613. (2020)

Soreq's Lab: A lncRNA survey finds increases in neuroprotective LINC‐PINT in Parkinson’s disease substantia nigra

Alon Simchovitz, Mor Hanan, Nadav Yayon, Songhua Lee, Estelle R. Bennett, David S. Greenberg, Sebastian Kadener, Hermona Soreq

Aging Cell. 2020; 19:e13115. (2019)

January 2020

Mezer’s Lab | Meshorer’s Lab | Sompolinsky’s Lab

Mezer's Lab: Subdividing the superior longitudinal fasciculus using local quantitative MRI

Roey Schurr, Ady Zelman, Aviv A. Mezer

NeuroImage, Volume 208, 2020, 116439, ISSN 1053-8119, (2019)

Meshorer's Lab: Progerin-Induced Transcriptional Changes in Huntington's Disease Human Pluripotent Stem Cell-Derived Neurons

Dorit Cohen-Carmon, Matan Sorek, Vitaly Lerner, Mundackal S. Divya, Malka Nissim-Rafinia, Yosef Yarom & Eran Meshorer

Mol Neurobiol. 2020 Mar;57(3):1768-1777. (2019)

Sompolinsky's Lab: Functional diversity among sensory neurons from efficient coding principles

Julijana Gjorgjieva, Markus Meister, Haim Sompolinsky

PLOS Computational Biology 15(11): e1007476. (2019)

December 2019

Burak’s Lab | Citri’s Lab | Joshua’s Lab

Burak's Lab: Velocity coupling of grid cell modules enables stable embedding of a low dimensional variable in a high dimensional neural attractor

Noga Mosheiff, Yoram Burak

Proceedings of the National Academy of Sciences Sep 2020, 117 (38) 23304-23310 (2019)

Citri's Lab: Subregion-specific rules govern the distribution of neuronal immediate-early gene induction

Ben Jerry Gonzales, Diptendu Mukherjee, Reut Ashwal-Fluss, Yonatan Loewenstein, Ami Citri

Proceedings of the National Academy of Sciences Sep 2020, 117 (38) 23304-23310 (2019)

Joshua's Lab: Cerebellar climbing fibers encode expected reward size

Noga Larry, Merav Yarkoni, Adi Lixenberg, Mati Joshua

eLife 2019;8:e46870 (2019)

September 2019

Loewenstein’s Lab | Meshorer’s Lab | Mezer’s Lab

Loewenstein's Lab: Idiosyncratic choice bias naturally emerges from intrinsic stochasticity in neuronal dynamics

Lior Lebovich, Ran Darshan, Yoni Lavi, David Hansel* and Yonatan Loewenstein*

Nat Hum Behav 3, 1190–1202 (2019). (2019)

Meshorer's Lab: Open chromatin structure in PolyQ disease-related genes: a potential mechanism for CAG repeat expansion in the normal human population

Matan Sorek, Lea R Z Cohen, Eran Meshorer

NAR Genomics and Bioinformatics, Volume 1, Issue 1, April 2019, Page e3 (2019)

Mezer's Lab: Tractography optimization using quantitative T1 mapping in the human optic radiation

Roey Schurr, Shir Filo, Aviv A. Mezer

NeuroImage, Volume 202, 2019, 116121, ISSN 1053-8119, (2019)

August 2019

Ahissar’s Lab

Ahissar's Lab: Benefits from morphological regularities in dyslexia are task dependent

Eva Kimel and Merav Ahissar

Journal of Experimental Psychology: Learning, Memory, and Cognition on May (2019)

July 2019

Hochstein’s Lab | Kalcheim’s Lab | Loewenstein’s Lab

Hochstein's Lab: Relating categorization to set summary statistics perception

Noam Khayat & Shaul Hochstein

Attention, Perception, & Psychophysics on June (2019)

Kalcheim's Lab: YAP promotes neural crest emigration through interactions with BMP and Wnt activities

Deepak Kumar, Erez Nitzan and Chaya Kalcheim

Cell Communication and Signaling on June (2019)

Loewenstein's Lab: From Choice Architecture to Choice Engineering

Ohad Dan and Yonatan Loewenstein

Nature Communications on June (2019)

June 2019

Nelken’s Lab | Prut’s Lab | Citri’s Lab

Nelken's Lab: Filters: When, Why, and How (Not) to Use Them

Alainde Cheveigné and Israel Nelken

Neuron, Volume 102, Issue 2, 2019, Pages 280-293, ISSN 0896-6273, (2019)

Prut's Lab: Reversible block of cerebellar outflow reveals cortical circuitry for motor coordination

Abdulraheem Nashef, Oren Cohen, Ran Harel, Zvi Israel and Yifat Prut

Cell Reports, Volume 27, Issue 9, 2608 - 2619.e4 (2019)

Citri's Lab: The role of the genome in experience-dependent plasticity: Extending the analogy of the genomic action potential

David F. Clayton, Ina Anreiter, Maria Aristizabal, Paul W. Frankland, Elisabeth B. Binder, and Ami Citri

Proceedings of the National Academy of Sciences Sep 2020, 117 (38) 23252-23260 (2019)

May 2019

Binshtok’s Lab

Binshtok's Lab: Location and Plasticity of the Sodium Spike Initiation Zone in Nociceptive Terminals In Vivo

Robert H. Goldstein, Omer Barkai, Almudena I´n˜ igo-Portugue´ s, Ben Katz, Shaya Lev, Alexander M. Binshtok

Neuron, Volume 102, Issue 4, 2019, Pages 801-812.e5, ISSN 0896-6273 (2019)

April 2019

Goldberg’s Lab | Mezer’s Lab

Goldberg's Lab: Population dynamics and entrainment of basal ganglia pacemakers are shaped by their dendritic arbors

Lior Tiroshi, Joshua A. Goldberg

PLOS-Computational Biology on February 7 (2019)

Mezer's Lab: Modeling conduction delays in the corpus callosum using MRI-measured g-rat

Shai Berman, Shir Filo and Aviv A. Mezer

NeuroImage 195 on July (2019)

March 2019

Tishby’s Lab | Ahissar’s Lab

Naftali Tishby: מגבלות הבינה המלאכותית בחיזוי התנהגות אנושית

Naftali Tishby

Ahissar's Lab: Perceptual bias reveals slow-updating in autism and fast-forgetting in dyslexia

Itay Lieder, Vincent Adam, Or Frenkel, Sagi Jaffe-Dax, Maneesh Sahani, Merav Ahissar

Nature Neuroscience Volume 22, pages 256–264 (2019)

January 2019

Joshua’s Lab

Joshua's Lab: Encoding of reward and decoding movement from the frontal eye field during smooth pursuit eye movements

Adi Lixenberg and Mati Joshua

JNeurosci Journal of Neuroscience 5 December 2018, 38 (49) (2018)

November 2018

Loewenstein’s Lab | Joshua’s Lab | Mezer’s Lab

Loewenstein's Lab: Striatal action-value neurons reconsidered

Lotem Elber-Dorozko and Yonatan Loewenstein

eLIFE on May (2018)

Joshua's Lab: Coordinated cerebellar climbing fiber activity signals learned sensorimotor predictions

William Heffley, Eun Young Song, Ziye Xu, Benjamin N. Taylor, Mary Anne Hughes, Andrew McKinney, Mati Joshuaand Court Hull

Nature Neuroscience volume 21, September (2018)

Mezer's Lab: Tractography optimization using quantitative t1 mapping in the human optic radiation

Roey Schurr, Duan Yiran, Anthony M. Norcia, Shumpei Ogawa, Jason D. Yeatman, Aviv A. Mezer

Neuroimage181 on November (2018)

'Ahiam 2nd' by Boaz Vaadia