Baruch Minke Lab

ELSC Members

Baruch Minke

Professor Emeritus

Phone: +972-2-6758407
Fax: +972-2-6439736
Mobile: +972-54-7961151
Address: Department of Medical Neurobiology, Faculty of Medicine,
Hadassah Ein-Kerem Campus, The Hebrew University of Jerusalem
Research Group of TRP Channels in Vision and Pain

My investigations have created a new field of research. I co-discovered a new type of ion channel, which I designated the Transient Receptor Potential or in short the TRP channel, as a result of my studies on phototransduction and vision in fruit flies (Drosophila melanogaster). I investigated the biophysical and biochemical properties of TRP channels in fruit fly eyes and identified together with the late Prof. Zvi Selinger phospholipase C as a crucial component of the Drosophila TRP signaling pathway. The principles that we found are common to numerous sensory (e.g. temperature, pain and taste sensations) and motor systems (properties of Purkinje neurons in the cerebellum), thus laying the foundation for the study of molecules that underlie mechanisms of TRP and pain, originally initiated by Prof. David Julius. Today we have extended our research to the first identified loss of function mutation in human TRPV1 channel that govern at least several of the human body’s regulatory processes related inflammatory pain and to noxious heat detection. Our major aim is to decipher the critical roles of TRP channels in invertebrate vision and of TRPV1 in human somatosensory physiology.

ELSC-Seminars-General
Elisheva Rhodes-Mordov
PhD Student
ELSC-Seminars-General
Rachel Zaguri
PhD Student
ELSC-Seminars-General
Rita Gutotov
PhD Student
ELSC-Seminars-General
Tal Brandwine
PhD Student
Ben Katz
Ben Katz PhD
Research Associate
Brandwine Tal, Ifrah Reut, Bialistoky Tzofia, Zaguri Rachel, Rhodes-Mordov Elisheva, Mizrahi-Meissonnier Liliana, Sharon Dror, Katanaev Vladimir L., Gerlitz Offer, Minke Baruch

Frontiers in Molecular Neuroscience (2021)

Katz, B., Pak, W. L., and Minke, B.

Oxford University New York, NY 10016, Oxford Handbooks Online (In Press) (2019)

Gutorov R, Peters M, Katz B, Brandwine T, Barbera NA, Levitan I, Minke B

Frontiers in Pharmacology 10, 1487 (2019)

Katz B, Minke B.

Progress in Retinal and Eye Research, Volume 66, Pages 200-219 (2018)

Katz, B., Payne, R., and Minke, B.

Neurobiology of TRP Channels, T. Rosenbaum, Editor, CRC Press/Taylor and Francis Group (2017)

Voolstra O, Rhodes-Mordov E, Katz B, Bartels JP, Oberegelsbacher C, Schotthöfer SK, Yasin B, Tzadok H, Huber A, Minke B.

Journal of Neuroscience, 37 (15) 4213-4224 (2017)

Katz B, Voolstra O, Tzadok H, Yasin B, Rhodes-Modrov E, Bartels JP, Strauch L, Huber A, Minke B.

Channels (Austin), 11(6):678-685. (2017)

Katz B*, Gutorov R*, Rhodes-Mordov E, Hardie RC, Minke B.

Journal of Visualized Experiments, (124). (2017)

Yasin B, Kohn E, Peters M, Zaguri R, Weiss S, Schopf K, Katz B, Huber A, Minke B.

Journal of Biological Chemistry, 292(9):3624-3636. (2017)

Peters M, Katz B, Lev S, Zaguri R, Gutorov R, Minke B.

Current Topics in Membranes, 80:233-254. (2017)

Kohn E, Katz B, Yasin B, Peters M, Rhodes E, Zaguri R, Weiss S, Minke B.

J Neurosci. 2015 Feb 11;35(6):2530-46 (2015)

Weiss, S. and Minke B.

Channels, Volume 9, Issue 1, pages 14-20 (2015)

Katz B, Oberacker T, Richter D, Tzadok H, Peters M, Minke B, Huber A.

J Cell Sci. 2013 Jul 15;126(Pt 14):3121-33 (2013)

Lev S, Katz B, Minke B

Channels, Volume 6, Issue 2 (2012)

Weiss S, Kohn E, Dadon D, Katz B, Peters M, Lebendiker M, Kosloff M, Colley NJ, Minke B.

J Neurosci. 2012 Oct 17;32(42):14696-708 (2012)

Peters M., Trembovler V., Alexandrovich A., Parnas M., Birnbaumer L., Minke B., Shohami E

Journal of Neurotrauma, Vol. 29, No. 18 (2012)

Minke B, Peters M

Science, Vol. 331, Issue 6022, pp. 1272-1273 (2011)

Richter D., Katz B., Oberacker T., Tzarfaty V., Belusic G., Minke B., Huber A

The Journal of Biological Chemistry, 286, 34234-34243 (2011)

Minke B

Journal of Neurogenetics, Volume 24, Issue 4 (2010)

Lev S. and Minke B

Methods in Enzymology, Volume 484, Pages 591-612 (2010)

Lev S., Zeevi D. A., Frumkin A., Offen-Glasner V., Bach G. and Minke B

The Journal of Biological Chemistry, 285, 2771-2782 (2010)

Dadon D. and Minke B

The International Journal of Biochemistry & Cell Biology, Volume 42, Issue 9, Pages 1430-1445 (2010)

Parnas M, Katz B., Lev S., Tzarfaty V., Dadon D., Gordon-Shaag, A., Metzner H., Yaka R. and Minke B

Journal of Neuroscience, 29 (8) 2371-2383 (2009)

Katz B and Minke B

Frontiers in Cellular Neuroscience (2009)

Parnas M., Peters M., Dadon D., Lev S., Vertkin I., Slutsky I. and Minke B

Cell Calcium, Volume 45, Issue 3, Pages 300-309 (2009)

Frechter S., Elia N., Tzarfaty V., Selinger Z. and Minke B

Journal of Neuroscience, 27 (21) 5571-5583 (2007)

Parnas M., Katz B. and Minke B

The Journal of General Physiology, 129 (1) 17-28 (2007)

Minke B

Cell Calcium, Volume 40, Issue 3, Pages 261-275 (2006)

Meyer NE, Joel-Almagor T, Frechter S, Minke B, Huber A

Journal of Cell Science, 119: 2592-2603 (2006)

Frechter, S and Minke B

Journal of Physiology-Paris Volume 99, Issues 2–3, Pages 133-139 (2006)

Minke B. and M. Parnas

Annual Review of Physiology, Volume 68, pp 649-684 (2006)

Chorna-Ornan I. , Tzarfati, V., Ankri-Eliahoo, G., Joel-Almagor, T., Huber A., Payre, F. and B Minke

The Journal of Cell Biology, 171 (1) 143-152 (2005)

Elia, N., Frechter, S., Minke, B, and Selinger, Z

The Journal of Cell Biology, 171 (3) 517-526 (2005)

Ikhine , R. Corna-Ornan, I. Zars, T. D. Elagina, R. B. Elia, N. Cheng, Y. Selinger, Z. Minke, B. and Hyde, D. R

Journal of Neuroscience, 24 (10) 2516-2526 (2004)

Agam, K., Frechter, S. and Minke, B

Cell Calcium, Volume 35, Issue 2, Pages 87-105 (2004)

Minke, B. and Agam, K

Cell Calcium, Volume 33, Issues 5–6, Pages 395-408 (2003)

Kosloff, M. Elia, N. Joel-Almagor, T. Timberg, R. Zars T. D. Hyde, D. R. Minke, B. and Selinger, Z

The EMBO Journal, 22, 459-468 (2003)

Minke, B. and Cook, B

Physiol. Rev. 82:429-472 (2002)

Bähner, M., Frechter, S., Da Silva, N., Minke, B., Paulsen, R. and Huber, A

Neuron, Volume 34, Issue 1, Pages 83-93 (2002)

Minke, B

Cellular and Molecular Neurobiology, Volume 21, Issue 6, pp 629–643 (2001)

Chorna-Ornan, I., Joel-Almagor, T., Cohen Ben-Ami, H., Frechter, S., Gillo, B., Selinger, Z., Gill, D.L. , and Minke, B

Journal of Neuroscience, 21 (8) 2622-2629 (2001)

Cook B, Bar-Yaacov M, Cohen Ben-Ami H, Goldstein R.E., Paroush Z, Selinger Z and Minke B

Nature Cell Biology, volume 2, pages 296–301 (2000)

Yoon J, Cohen Ben-Ami H, Hong YS, Park S, Strong LLR, Bowman J, Geng C, Baek K, Minke B, Pak WL

Journal of Neuroscience, 20 (2) 649-659 (2000)

Agam, K., M. von-Campenhausen, S. Levy, H. Cohen Ben-Ami, B. Cook, K. Kirschfeld and B. Minke

Journal of Neuroscience, 20 (15) 5748-5755 (2000)

Cook, B and Minke, B

Cell Calcium, Volume 25, Issue 2, Pages 161-171 (1999)

Arnon, A., Cook, B.,Gillo, B., Montell, C., Selinger, Z. and Minke, B

PNAS, 94 (11) 5894-5899 (1997)

Arnon, A., Cook, B., Montell, C., Selinger, Z. and Minke, B

Science, Vol. 275, Issue 5303, pp. 1119-1121 (1997)

Minke, B. and Selinger, Z

Current Opinion in Neurobiology, Volume 6, Issue 4, Pages 459-466 (1996)

Minke, B. and Selinger, Z

Molecular Neurobiology, Volume 12, Issue 2, pp 163–180 (1996)

Gillo, B., Sealfon, S.C. and Minke, B

Journal of Photochemistry and Photobiology B: Biology, Volume 35, Issues 1–2, Pages 77-82 (1996)

Ben-Oren, I., Peleg, G., Lewis, A., Minke, B. and Loew, L

Biophysical Journal, Volume 71, Issue 3, Pages 1616-1620 (1996)

Gillo, B, Chorna, I., Cohen, H., Cook, B., Manistersky, I, Chorev, M., Arnon, A., Pollock, A., Selinger, Z. and Minke, B

PNAS, 93 (24) 14146-14151 (1996)

Pollock, J., Arnon, A., Peretz, A., Nichols, D., Mojet, M.H., Hardie, R.C. and Minke, B

Journal of Neuroscience, 15 (5) 3747-3760 (1995)

Hardie, R.C. and Minke, B

Cell Calcium Volume 18, Issue 4, Pages 256-274 (1995)

Porter, J.A., Minke, B. and Montell, C

The EMBO Journal, Volume 14, Issue 18, Pages 4450-4459 (1995)

Barash, S. and Minke, B

Comments in Theoretical Biology. 3: 229-263 (1994)

Peretz, A., Suss-Toby, E., Rom-Glas, A., Arnon, A., Payne, R. and Minke, B

Neuron, Volume 12, Issue 6, p1257-1267 (1994)

Hardie, R.C. and Minke, B

Journal of General Physiology, vol. 103 no. 3 389-407 (1994)

Peretz, A., Sandler, C., Kirschfeld, K., Hardie, R.C. and Minke B

Journal of General Physiology, vol. 104 no. 6 1057-1077 (1994)

Hardie, R.C. and Minke, B

Journal of General Physiology, vol. 103 no. 3 409-427 (1994)

Sahly, I., Schroder, W. Zierold, A. and Minke, B

Visual Neuroscience, Volume 11, pp. 763-772 (1994)

Selinger, Z. Doza, Y.N. and Minke, B

Biochimica et Biophysica Acta (BBA) – Molecular Cell Research, Volume 1179, Issue 3, Pages 283-299 (1993)

Byk, T., M. Bar-Yaacov, Y. Doza, B. Minke and Z. Selinger

PNAS, 90 (5) 1907-1911 (1993)

Hardie, R.C., Suss-Toby, E., Rom-Glas, A., Peretz, A., Selinger, Z. and Minke, B

Nature, 363, 634–637 (1993)

Hardie, R.C. and Minke, B

Trends in Neurosciences, Volume 16, Issue 9,, Pages 371-376 (1993)

Hardie, R.C., Peretz, A., Pollock, J.A., and Minke, B

Proceedings of the Royal Society B, Volume 252, Issue 1335 (1993)

Minke, B. and Z. Selinger

Soc Gen Physiol Ser. 47:201-17. (1992)

Hardie, R.C. and B. Minke

Neuron, Volume 8, Issue 4, Pages 643-651 (1992)

Rom-Glas, A., C. Sandler, K. Kirschfeld, and B. Minke

Journal of General Physiology, vol. 100 no. 5 767-781 (1992)

Minke, B., C. Rubinstein, I. Sahly, S. Bar-Nachum, E. Suss, J. Kleiman, T. Byke, and Z. Selinger

Signal Transduction in Photoreceptor Cells pp 281-298 (1992)

Minke, B. and Z. Selinger

Intracellular Messengers pp 517-563 (1992)

Doza, N.Y., B. Minke and Z. Selinger

European Journal of Biochemistry, Volume 209, Issue 3, Pages 1035-1040 (1992)

Werner, U., E. Suss-Toby, A. Rom and B. Minke

Journal of Comparative Physiology A, Volume 170, Issue 4, pp 427–434 (1992)

Sahly, I., S. Bar-Nachum, E. Suss-Toby, A. Rom, A. Peretz, J. Kleiman, T. Byke, Z. Selinger and B. Minke

PNAS, 89 (1) 435-439 (1992)

Minke, B. and Z. Selinger

Progress in Retinal Research, Volume 11, Pages 99-124 (1991)

Minke, B. and R. Payne

Journal of Neuroscience, 11 (4) 900-909 (1991)

Suss-Toby, E., Z. Selinger, and B. Minke

Journal of General Physiology, vol. 98 no. 4 849-868 (1991)

Minke, B., C. Rubinstein, I. Sahly, S. Bar-Nachum, R. Timberg and Z. Selinger

PNAS, 87 (1) 113-117 (1990)

Rubinstein, C., S. Bar-Nachum, Z. Selinger, and B. Minke

Visual Neuroscience, Volume 2, Issue 6, pp. 529-539 (1989)

Rubinstein, C., S. Bar-Nachum, Z. Selinger, and B. Minke

Visual Neuroscience, Volume 2, Issue 6, pp. 541-551 (1989)

Suss, E., S. Barash, D.G. Stavenga, H. Stieve, Z. Selinger, and B. Minke

Journal of General Physiology, vol. 94 no. 3 465-491 (1989)

Selinger, Z. and B. Minke

Cold Spring Harb Symp Quant Biol. 53: 333-341 (1988)

Barash, S., E. Suss, D.G. Stavenga, Z. Selinger, C. Rubinstein, and B. Minke

Journal of General Physiology, vol. 92 no. 3 307-330 (1988)

Selinger, A., O. Devary, A. Blumenfeld, O. Heichal, S. Barash and B. Minke

Prog Clin Biol Res. 249:169-78. (1987)

Devary, O., O. Heichal, A. Blumenfeld, D. Cassel, E. Suss, S. Barash, C. Rubinstein, B. Minke and Z. Selinger

PNAS, 84 (19) 6939-6943 (1987)

Minke, B

Isr J Med Sci. 23(1-2):61-8. (1987)

Almagor, E., P. Hillman and B. Minke

Journal of General Physiology, vol. 87 no. 3 407-423 (1986)

Almagor, E., P. Hillman and B. Minke

Journal of General Physiology, vol. 87 no. 3 391-405 (1986)

Minke, B

Dahlem Workshop Reports (Life Sciences Research Report), vol 34, pp 241-265 (1986)

Minke, B. and M. Tsacopoulos

Vision Research, Volume 26, Issue 5, Pages 679-690 (1986)

Minke, B. and R.S. Stephenson

Journal of Comparative Physiology A, Volume 156, Issue 3, pp 339–356 (1985)

Blumenfeld, A., J. Erusalimsky, O. Heichal, Z. Selinger, and B. Minke

PNAS, 82 (20) 7116-7120 (1985)

Minke, B. and K. Kirschfeld

Journal of Comparative Physiology A, Volume 154, Issue 2, pp 175–187 (1984)

Minke, B. and E. Armon

Vision Research, Volume 24, Issue 2, Pages 109-115 (1984)

Hillman, P., S. Hochstein and B. Minke

Physiological Reviews, Volume 63, Pages 668-772 (1983)

Minke, B

Journal of comparative physiology, Volume 151, Issue 4, pp 483–486 (1983)

Armon, E. and B. Minke

Biophysics of structure and mechanism, Volume 9, Issue 4, pp 349–357 (1983)

Minke, B

Journal of General Physiology, vol. 79 no. 3 361-385 (1982)

Franceschini, N., K. Kirschfeld and B. Minke

Science, Vol. 213, Issue 4513, pp. 1264-1267 (1981)

Minke, B. and E. Armon

Photochemistry and Photobiology, Volume 32, Issue 4, Pages 553-562 (1980)

Minke, B. and K. Kirschfeld

Journal of General Physiology, vol. 75 no. 4 381-402 (1980)

Almagor, E., P. Hillman, and B. Minke

Biophysics of structure and mechanism, Volume 5, Issue 2–3, pp 243–248 (1979)

Minke, B

Biophysics of structure and mechanism, Volume 5, Issue 2–3, pp 163–174 (1979)

Minke, B. and K. Kirschfeld

Journal of General Physiology, vol. 73 no. 5 517-540 (1979)

Kirschfeld, K., R. Feiler and B. Minke

Zeitschrift für Naturforschung C, Volume 33, Issue 11-12, Pages 1009–1010 (1978)

Minke, B., S. Hochstein and P. Hillman

Biological Cybernetics, Volume 30, Issue 1, pp 33–43 (1978)

Hochstein, S., B. Minke, P. Hillman and B. Knight

Biological Cybernetic, Volume 30, Issue 1, pp 23–32 (1978)

Minke, B. and K. Kirschfeld

Journal of General Physiology, vol. 71 no. 1 37-45 (1978)

Kirschfeld, K., N. Franceschini and B. Minke

Nature, 269, 386–390 (1977)

Minke, B

Biophysics of structure and mechanism, Volume 3, Issue 1, pp 59–64 (1977)

Hillman, P.S. Hochstein, and B. Minke

Journal of General Physiology, vol. 68 no. 2 227-245 (1976)

Minke, B., C.-F. Wu and W.L. Pak

Journal of comparative physiology, Volume 98, Issue 4, pp 345–355 (1975)

Minke, B., C-F, Wu, and W.L. Pak

Nature, 258, 84–87 (1975)

Minke, B., S. Hochstein, and P. Hillman

Biophysical Journal, Volume 14, Issue 6, Pages 490-512 (1974)

Hillman, P., F.A. Dodge, Jr., S. Hochstein, B. Knight and B. Minke

Journal of General Physiology, vol. 62 no. 1 77-86 (1973)

Minke, B., S. Hochstein and P. Hillman

Journal of General Physiology, vol. 62 no. 6 787-791 (1973)

Minke, B., S. Hochstein, and P. Hillman

Journal of General Physiology, vol. 62 no. 1 87-104 (1973)

Hochstein, S., B. Minke, and P. Hillman

Journal of General Physiology, vol. 62 no. 1 105-128 (1973)

Hochstein, S., B. Minke and P. Hillman

The Visual System pp 65-73 (1972)

Minke, B., and E. Auerbach

Experimental Brain Research, Volume 14, Issue 4, pp 409–422 (1972)

Hillman, P., S. Hochstein and B. Minke

Science, Vol. 175, Issue 4029, pp. 1486-1488 (1972)

At this time there are no available positions in the lab.
Honors:
EMET Prize
Prince of Asturias Award (from the current King of Spain)

Baruch Minke

Professor Emeritus

Phone: +972-2-6758407
Fax: +972-2-6439736
Mobile: +972-54-7961151
Address: Department of Medical Neurobiology, Faculty of Medicine,
Hadassah Ein-Kerem Campus, The Hebrew University of Jerusalem

“Working memory”