Eran Meshorer Lab

ELSC Members

Arthur Gutterman Family Chair in Stem Cell Biology Endowment Fund
Epigenetics, stem cells, & neurons

The Meshorer lab is studying

1. Epigenetic regulation in stem cells and differentiation;
2. Neurodegenerative diseases (e.g. HD) using pluripotent stem cell models;
3. Paleo-epigenetics: reconstructing DNA methylation in archaic genomes.

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Eran Meshorer

Professor

Email: eran.meshorer@mail.huji.ac.il
Phone: +972-2-6585161
Eran Meshorer CV
Eran Meshorer
@meshorer1
Address: Department of Genetics, The Institute of Life Sciences, Silberman Building, Room 2-541. The Hebrew University of Jerusalem, Edmond J. Safra Campus, Givat Ram. Yael Riback, Lab administrator, 02-6585144
http://meshorerlab.huji.ac.il/
Arthur Gutterman Family Chair in Stem Cell Biology Endowment Fund
Epigenetics, stem cells, & neurons

The Meshorer lab is studying

1. Epigenetic regulation in stem cells and differentiation;
2. Neurodegenerative diseases (e.g. HD) using pluripotent stem cell models;
3. Paleo-epigenetics: reconstructing DNA methylation in archaic genomes.

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Ben Title
PhD Student
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Vitaly Lerner
PhD Student
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Inbar Kotzer
PhD Student
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Nora Vrieler
PhD Student
ELSC-Seminars-General
Yasmin Yarden-Rabinowitz
. Cohen-Carmon, D., M. Sorek, V. Lerner, M. S. Divya, M. Nissim-Rafinia, Y. Yarom, and E. Meshorer

Correction to: Progerin-Induced Transcriptional Changes in Huntington's Disease Human Pluripotent Stem Cell-Derived Neurons

Mol Neurobiol (2020)

. Suliman-Lavie R, Title B, Cohen Y, Hamada N, Tal M, Tal N, Monderer-Rothkoff G, Gudmundsdottir B, Gudmundsson KO, Keller JR, Huang GJ, Nagata KI, Yarom Y, Shifman S.

Pogz deficiency leads to transcription dysregulation and impaired cerebellar activity underlying autism-like behavior in mice.

Nat Commun. (2020)

Yaara Lefler, Oren Amsalem, Nora Vrieler, Idan Segev, Yosef Yarom

Using subthreshold events to characterize the functional architecture of the electrically coupled inferior olive network

eLife (2020)

Yarden-Rabinowitz Y, Yarom Y

Delayed Complex Spike Response Evoked by Conditioned Stimulus Encodes Movement Onset Time and Is Determined by Intrinsic Inferior Olive Properties

Frontiers in Systems Neuroscience 13:50 (2019)

Byk H, Huang GJ, Iwakura Y, Yarom Y

Large Scale Calcium Imaging of the Cerebellar Vermis During Sensory Stimulus Unravels Two Response’s Components That Differ in Their Spatiotemporal Properties

Frontiers in Systems Neuroscience, 13:18 (2019)

Cohen-Carmon D, Sorek M, Lerner V, Nissim-Rafinia M, Yarom Y, Meshorer E

Progerin-Induced Transcriptional Changes in Huntington’s Disease Human Pluripotent Stem Cell-Derived Neurons

Molecular Neurobiology (2019)

Nora Vrieler, Sebastian Loyola, Yasmin Yarden-Rabinowitz, Jesse Hoogendorp, Nikolay Medvedev, Tycho M. Hoogland, Chris I. De Zeeuw, Erik De Schutter, Yosef Yarom, Mario Negrello, Ben Torben-Nielsen, Marylka Yoe Uusisaari

Variability and directionality of inferior olive neuron dendrites revealed by detailed 3D characterization of an extensive morphological library

Brain Structure and Function, pp 1–19 (2019)

Lefler Y., Amsalem O., Segev I., Yarom Y.

Using subthreshold events to characterize the functional architecture of electrically coupled networks

bioRxiv preprint (2018)

Zylbertal, A, Yarom Y, Wagner S.

Synchronous Infra-Slow Bursting in the Mouse Accessory Olfactory Bulb Emerge from Interplay between Intrinsic Neuronal Dynamics and Network Connectivity

The Journal of neuroscience : the official journal of the Society for Neuroscience. 37(10):2656-2672. (2017)

Yarden-Rabinowitz Y., Yarom Y.

In vivo analysis of synaptic activity in cerebellar nucleineurons unravels the efficacy of excitatory inputs

J Physiol 595.17 (2017) pp 5945–5963 (2017)

Wigderson, E, Nelken I, Yarom Y.

Early multisensory integration of self and source motion in the auditory system.

Proc Natl Acad Sci U S A, 113(29): 8308–8313 (2016)

Grodzinsky Y., Nelken I.

The neural code that makes us human

Science. 2014 Feb 28;343(6174):978-9. (2014)

Anat Yaron-Jakoubovitch, Christof Koch, Idan Segev, and Yosef Yarom

The unimodal distribution of subthreshold, ongoing activity in cortical networks

Front Neural Circuits. 7: 116. (2013)

Benjamin Torben-Nielsen , Idan Segev, Yosef Yarom

The Generation of Phase Differences and Frequency Changes in a Network Model of Inferior Olive Subthreshold Oscillations

PLoS Computational Biology, Volume 8 | Issue 7 | e1002580 (2012)

Yaron-Jakoubovitch A., Jacobson G., Koch Ch., Segev I. and Yarom Y.

A paradoxical isopotentiality: a spatially uniform noise spectrum in neocortical pyramidal cells

Front Cell Neurosci. 13;2:3 (2008)

Yonatan Loewenstein, Séverine Mahon, Paul Chadderton, Kazuo Kitamura, Haim Sompolinsky, Yosef Yarom & Michael Häusser

Purkinje cells in awake behaving animals operate in stable upstate membrane potential

Nature Neurosciencevolume 9, page461 (2006)

Yonatan Loewenstein; Séverine Mahon; Paul Chadderton; Kazuo Kitamura; Haim Sompolinsky; Yosef Yarom; Michael Häusser

Bistability of cerebellar Purkinje cells modulated by sensory stimulation

Nature Neuroscience, Volume 8, p.202–211 (2005)

Jacobson GA, Diba K, Yaron-Jakoubovitch A, Oz Y, Koch C, Segev I, Yarom Y

voltage noise of rat neocortical pyramidal neurones

J Physiol. 2005 Apr 1; 564(Pt 1): 145–160. (2005)

Häusser M, Raman IM, Otis T, Smith SL, Nelson A, du Lac S, Loewenstein Y, Mahon S, Pennartz C, Cohen I, Yarom Y.

The beat goes on: spontaneous firing in mammalian neuronal microcircuits

J Neurosci. 2004 Oct 20;24(42):9215-9. (2004)

Loewenstein Y, Yarom Y, Sompolinsky H.

The generation of oscillations in networks of electrically coupled cells

Proc Natl Acad Sci U S A. 2001 Jul 3;98(14):8095-100 (2001)

Manor Y, Rinzel J, Segev I, Yarom Y.

Low amplitude oscillations in the inferior olive: A model based on electrical coupling of neurons with heterogeneous channel density

J Neurophysiol. 1997 May;77(5):2736-52. (1997)

Rapp M, Yarom Y, Segev I.

Modeling back propagating action potential in weakly excitable dendrites of neocortical pyramidal cells

Proc Natl Acad Sci U S A. 1996 Oct 15;93(21):11985-90 (1996)

Yoram Gutfreund, Tamar Flash, Yosef Yarom, Graziano Fiorito, Idan Segev and Binyamin Hochner

Organization of octopus arm movement: A model system for studying the control of flexible arm

Journal of Neuroscience 15 November 1996, 16 (22) 7297-7307 (1996)

Gutfreund Y, Yarom Y, Segev I.

Subthreshold oscillations and resonant frequency in guinea pig cortical neurons: physiology and modeling

J Physiol. 1995 Mar 15;483 ( Pt 3):621-40. (1995)

Rapp M, Segev I, Yarom Y.

Physiology, morphology and detailed passive models of cerebellar Purkinje cells

J Physiol. 1994 Jan 1;474(1):101-18. (1994)

Rapp M., Yarom Y., and Segev I.

The impact of parallel fiber background activity on the cable properties of cerebellar Purkinje cells

Neural Computation; Volume: 4 , Issue: 4 , July 1992 (1992)

Nitzan R., Segev I. and Yarom Y.

Voltage behavior along the irregular dendritic structure of morphologically and physiologically characterized vagal motoneurons of the guinea pig

JOURNAL OF NEUROPHYSIOLOGY Vol. 63. No. 2, February 1990. (1990)

At this time there are no available positions in the lab.
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Yosef Yarom

Professor Emeritus

Email: yosef.yarom@mail.huji.ac.il
Phone: +972-2-6585172
Fax: +972-2-6586296
Address: The Alexander Silberman Institute of Life Sciences,
Department of Neurobiology
Edmond J. Safra Campus, The Hebrew University of Jerusalem 9190401
לחצו למעבר להרשמה

“Working memory”

New exhibition titled “Working memory” by the artist Alon kedem and in collaboration with ELSC Prof. Leon Deouell. In the picture: Moshe Lion, the mayor of Jerusalem and Prof. Asher Cohen, the president of The Hebrew University of Jerusalem.