Post Docs
Alkesh Yadav
My primary research interest is understanding information processing in living systems. In my PhD research, done at NCBS, India, I developed a mathematical model for the synthesis of glycans – molecules that carry the information of cell type identity. We showed that the requirement of producing a high fidelity distribution of glycans puts constraints on the synthesis machinery, in terms of the number of compartments, and number and specificity of enzymes. Prior to this, I did my undergrad (Master’s in Science) in Physics from University of Mumbai, India.
In ELSC, at Jonathan Kadmon’s lab, I am working on developing a theory to analyze the effects of network motifs and non-equilibrium driving on the dynamics of a network of neurons.
2. Gili Abramov*, Rona Shaharabani*, Omry Morag, Ram Avinery, Anat Haimovich, Inbal Oz, Roy Beck, Amir Goldbourt. Structural Effects of Single Mutations in a Filamentous Viral Capsid Across Multiple Length Scales, Biomacromolecules, 2017, 18 (8), pp 2258-2266. *Equal contribution. DOI: 10.1021/acs.biomac.7b00125
3. Assaf Harnoy, Marina Buzhor, Einat Tirosh, Rona Shaharabani, Roy Beck, Roey Amir. A Modular Synthetic Approach for Adjusting the Disassembly Rates of Enzyme-Responsive Polymeric Micelles, Biomacromolecule, 2017, 18 (4), pp 1218-1228. DOI: 10.1021/acs.biomac.6b01906
4. Merav Segal, Ram Avinery, Marina Buzhor, Rona Shaharabani, Assaf Harnoy, Einat Tirosh, Roy Beck, Roey Amir. Molecular Precision and Enzymatic Degradation: From Readily to Undegradable Polymeric Micelles by Minor Structural Changes, JACS, 2017, 139 (2), pp 803–810. DOI: 10.1021/jacs.6b10624
