Eilon Vaadia Lab

ELSC Members

Vaadia's Lab

Prof. Vaadia (Former (Founding) Director of ELSC (2009-2016) combines theory and experiments to the study brain sensorimotor functions The team at the lab uses brain-machine interfaces (BMI) electrical activity of neurons in brain circuits. In simple words, BMIs can read the to modulate and decipher the brain’s intention” from its activity and further; BMI can be used to detect in real-time electrical patterns involved in a brain disease, and re-adjust these patterns to ameliorate the disease.

Oren Peles, Uri Werner-Reiss, Hagai Bergman, Zvi Israel, Eilon Vaadia

Phase-Specific Microstimulation Differentially Modulates Beta Oscillations and Affects Behavior

Cell Reports Volume 30, Issue 8 (2020)

Ben Engelhard, Ran Darshan, Nofar Ozeri-Engelhard, Zvi Israel, Uri Werner-Reiss, David Hansel, Hagai Bergman, Eilon Vaadia

Neuronal activity and learning in local cortical networks are modulated by the action-perception state

bioRxiv (2019)

Lalazar, H. Abbott, L. and Vaadia, E.

Muscle and kinematic representations for arm and BMI control exist in orthogonal subspaces

Cosyne (2016)

Josef Musil, Darron Haylock, Matthew Hayhurst, Samuel Wilkinson, Xavier De Kestelier, Eilon Vaadia

Safra Neuron Screen

Advances in Architectural Geometry 2016 (2016)

Lalazar, H, Abbott LF, Vaadia E.

Tuning Curves for Arm Posture Control in Motor Cortex Are Consistent with Random Connectivity.

PLoS computational biology, Volume: 12, Issue: 5, e1004910 (2016)

Ben, E, Eilon V.

Spatial computation with gamma oscillations

Front Syst. Neuros, Volume: 8, Issue: 165 (2014)

Taubman H, Vaadia E, Paz R, Chechik G.

A Bayesian approach for characterizing direction tuning curves in the supplementary motor area of behaving monkeys

J Neurophysiol. 109(11):2842-51 (2013)

Engelhard B, Ozeri N, Israel Z, Bergman H, Vaadia E.

Inducing Gamma Oscillations and Precise Spike Synchrony by Operant Conditioning via Brain-Machine Interface

Neuron; 77(2):361-75 (2013)

Levy-Tzedek S, Novick I, Arbel R, Abboud S, Maidenbaum S, Vaadia E, Amedi A.

Cross-sensory transfer of sensory-motor information: visuomotor learning affects performance on an audiomotor task, using sensory-substitution

Sci Rep. 2012;2:949 (2012)

Zach N. Inbar D., Grinvald, Y. and Vaadia, E.

Single neurons in M1 and premotor cortex directly reflect behavioral interference

PLoS One. 2012;7(3):e32986. (2012)

Rosin B, Slovik M, Mitelman R, Rivlin-Etzion M, Haber SN, Israel Z, Vaadia E, Bergman H.

Closed-loop deep brain stimulation is superior in ameliorating Parkinsonism

Neuron, 72(2), 370-384 (2011)

Mandelblat-Cerf Y, Novick I, Vaadia E.

Expressions of multiple neuronal dynamics during sensorimotor learning in the motor cortex of behaving monkeys

PLoS One; 6(7):e21626. (2011)

Novick I, Vaadia E.

Just do it: action-dependent learning allows sensory prediction

PLoS One. 2011;6(10):e26020. (2011)

Braun DA, Aertsen A, Paz R, Vaadia E, Rotter S, Mehring C.

Online adaptation and over-trial learning in macaque visuomotor control

Front Comput Neurosci. 2011; 5: 27. (2011)

Mandelblat-Cerf Y, Novick I, Paz R, Link Y, Freeman S, Vaadia E.

The Neuronal Basis of Long-Term Sensorimotor Learning

Journal of Neuroscience 5 January 2011, 31 (1) 300-313 (2011)

15. Eisenberg M, Shmuelof L, Vaadia E, Zohary E.

The Representation of Visual and Motor Aspects of Reaching Movements in the Human Motor Cortex

Journal of Neuroscience, 31 (34) 12377-12384; (2011)

Fritzie Arce, Itai Novick, Yael Mandelblat-Cerf, Zvi Israel, Claude Ghez and Eilon Vaadia

Combined Adaptiveness of Specific Motor-Cortical Ensembles Underlies Learning

Journal of Neuroscience 14 April 2010, 30 (15) 5415-5425 (2010)

Arce F, Novick I, Vaadia E.

Discordant Tasks and Motor Adjustments Affect Interactions between Adaptations to Altered Kinematics and Dynamics

Front Hum Neurosci. 2010 Jan 4;3:65 (2010)

Eisenberg M, Shmuelof L, Vaadia E, Zohary E.

Functional Organization of Human Motor Cortex: Directional Selectivity for Movement

J Neurosci. 2010 Jun 30;30(26):8897-905 (2010)

Arce F, Novick I, Mandelblat-Cerf Y, Vaadia E.

Neuronal correlates of memory formation in motor cortex after adaptation to force field

J Neurosci. 2010 Jul 7;30(27):9189-98 (2010)

22. Birbaumer N and Vaadia E.

Brain computer Interface and Neurofeedback

Neuroscience (2009)

Arce F, Novick I, Shahar M, Link Y, Ghez C, Vaadia E.

Differences in context and feedback result in different trajectories and adaptation strategies in reaching

PLoS ONE. 4(1):e4214. Epub 2009 (2009)

Joshua, M, Adler A, Rosin B, Vaadia E, Bergman H.

Encoding of probabilistic rewarding and aversive events by pallidal and nigral neurons.

Journal of neurophysiology, Volume 101, Issue 2, Pages 758-772 (2009)

Eilon Vaadia, and Niels Birbaumer

Grand challenges of brain computer interfaces in the years to come

Front Neurosci. 2009 Sep; 3(2): 151–154 (2009)

Paz R, Vaadia E.

Learning from learning: what can visuomotor adaptations tell us about the neuronal representation of movement?

Adv Exp Med Biol. 2009;629:221-42. (2009)

Joshua M, Adler A, Prut Y, Vaadia E, Wickens JR, Bergman H.

Synchronization of midbrain dopaminergic neurons is enhanced by rewarding events

Neuron. 62(5):695-704 (2009)

Amir Globerson, Eran Stark, Eilon Vaadia, and Naftali Tishby

The minimum information principle and its application to neural code analysis

PNAS March 3, 2009 106 (9) 3490-3495; (2009)

Mandelblat-Cerf Y, Paz R, Vaadia E.

Trial-to-trial variability of single cells in motor cortices is dynamically modified during visuomotor adaptation

J Neurosci. 2009 Dec 2;29(48):15053-62 (2009)

Neta Zach, Dorrit Inbar, Yael Grinvald, Hagai Bergman and Eilon Vaadia

Emergence of novel representations in primary motor cortex and premotor neurons during associative learning

Journal of Neuroscience 17 September 2008, 28 (38) 9545-9556; (2008)

Rivlin-Etzion M, Marmor O, Saban G, Rosin B, Haber SN, Vaadia E, Prut Y, Bergman H.

Low-pass filter properties of basal ganglia cortical muscle loops in the normal and MPTP primate model of parkinsonism

J Neurosci. 2008 Jan 16;28(3):633-49. (2008)

Joshua, M, Adler A, Mitelman R, Vaadia E, Bergman H.

Midbrain dopaminergic neurons and striatal cholinergic interneurons encode the difference between reward and aversive events at different epochs of probabilistic classical conditioning trials.

Journal of Neuroscience, 28 (45) 11673-11684 (2008)

Lalazar H, Vaadia E.

Neural basis of sensorimotor learning: modifying internal models

Curr Opin Neurobiol. 2008 Dec;18(6):573-81. (2008)

Morris, Nevet, Arkadir, Vaadia and Bergman

Midbrain dopamine neurons encode decisions for future action

Nature Neuroscience volume 9, pages 1057–1063 (2006)

Paz R, Nathan C, Boraud T, Bergman H, Vaadia E.

Acquisition and generalization of visuomotor transformations by nonhuman primates

Exp Brain Res. 2005 Feb;161(2):209-19. (2005)

Rony Paz, Chen Natan, Thomas Boraud, Hagai Bergman and Eilon Vaadia

Emerging patterns of neuronal responses in supplementary and primary motor areas during sensorimotor adaptation

Journal of Neuroscience 23 November 2005, 25 (47) 10941-10951; (2005)

Rickert J, Oliveira SC, Vaadia E, Aertsen A, Rotter S, Mehring C.

Encoding of movement direction in different frequency ranges of motor cortical local field potentials

J Neurosci. 2005 Sep 28;25(39):8815-24. (2005)

Zach N, Kanarek N, Inbar D, Grinvald Y, Milestein T, Vaadia E.

Segregation between acquisition and long-term memory in sensorimotor learning

Eur J Neurosci. 2005 Nov;22(9):2357-62. (2005)

Shpigelman L, Singer Y, Paz R, Vaadia E.

Spikernels: predicting arm movements by embedding population spike rate patterns in inner-product spaces

Neural Comput. 2005 Mar;17(3):671-90. (2005)

Shpigelman, L. Crammer K., Paz, R., Vaadia E. And Singer Y

A Temporal Kernel-Based Model for Tracking Hand-Movements from Neural Activities

Neural Information Processing Systems (NIPS) (2004)

Morris G, Arkadir D, Nevet A, Vaadia E, Bergman H.

Coincident but distinct messages of midbrain dopamine and striatal tonically active neurons

Neuron. 43(1):133-43. (2004)

Mehring C, Nawrot MP, de Oliveira SC, Vaadia E, Schulze-Bonhage A, Aertsen A, Ball T.

Comparing information about arm movement direction in single channels of local and epicortical field potentials from monkey and human motor cortex

J Physiol Paris. 2004 Jul-Nov;98(4-6):498-506. (2004)

Bar-Gad I, Elias S, Vaadia E, Bergman H.

Complex locking rather than complete cessation of neuronal activity in the globus pallidus of a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated primate in response to pallidal microstimulation

J Neurosci. 2004 Aug 18;24(33):7410-9. (2004)

Arkadir D, Morris G, Vaadia E, Bergman H.

Independent coding of movement direction and reward prediction by single pallidal neurons

J Neurosci. 2004 Nov 10;24(45):10047-56. (2004)

Rony Paz, Eilon Vaadia

Learning-induced improvement in encoding and decoding of specific movement directions by neurons in the primary motor cortex

PLoS Biol. 2004 Feb; 2(2): e45. (2004)

Paz R, Vaadia E.

Specificity of sensorimotor learning and the neural code: neuronal representations in the primary motor cortex

J Physiol Paris. 2004 Jul-Nov;98(4-6):331-48. (2004)

Goldberg JA, Rokni U, Boraud T, Vaadia E, Bergman H.

Spike synchronization in the cortex/basal-ganglia networks of Parkinsonian primates reflects global dynamics of the local field potentials

J Neurosci. 2004 Jun 30;24(26):6003-10. (2004)

Rony Paz, Steven P Wise, Eilon Vaadia

Viewing and doing: similar cortical mechanisms for perceptual and motor learning

Trends in Neurosciences Volume 27, Issue 8, 1 August 2004, Pages 496-503 (2004)

Uri Rokni; Orna Steinberg; Eilon Vaadia; Haim Sompolinsky

Cortical representation of bimanual movements

J Neurosci. 2003 Dec 17;23(37):11577-86. (2003)

Mehring C., Rickert J., Vaadia E., Cardoso de Oliveira S., Aertsen A., Rotter S

Hints for a topographic map of tuning properties in primate motor cortex

1st International IEEE EMBS Special Topic Conference on Neural Engineering (2003)

Mehring C, Rickert J, Vaadia E, Cardosa de Oliveira S, Aertsen A, Rotter S.

Inference of hand movements from local field potentials in monkey motor cortex

Nat Neurosci. 2003 Dec;6(12):1253-4. Epub 2003 Nov 21. (2003)

Paz R, Boraud T, Natan C, Bergman H, Vaadia E.

Preparatory activity in motor cortex reflects learning of local visuomotor skills

Nat Neurosci. 2003 Aug;6(8):882-90. (2003)

Goldberg JA, Boraud T, Maraton S, Haber SN, Vaadia E, Bergman H.

Enhanced synchrony among primary motor cortex neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine primate model of Parkinson’s disease

J Neurosci. 2002 Jun 1;22(11):4639-53. (2002)

Steinberg O, Donchin O, Gribova A, Cardosa de Oliveira S, Bergman H, Vaadia E.

Neuronal populations in primary motor cortex encode bimanual arm movements

Eur J Neurosci. 2002 Apr;15(8):1371-80. (2002)

Donchin O, Gribova A, Steinberg O, Mitz AR, Bergman H, Vaadia E.

Single-unit activity related to bimanual arm movements in the primary and supplementary motor cortices

J Neurophysiol. 2002 Dec;88(6):3498-517. (2002)

A. Gribova, O. Donchin, H. Bergman, E. Vaadia, S. Cardoso de Oliveira

Timing of bimanual movements in human and non-human primates in relation to neuronal activity in primary motor cortex and supplementary motor area

Experimental Brain Research October 2002, Volume 146, Issue 3, pp 322–335 (2002)

Raz A, Frechter-Mazar V, Feingold A, Abeles M, Vaadia E, Bergman H.

Activity of pallidal and striatal tonically active neurons is correlated in mptp-treated monkeys but not in normal monkeys

J Neurosci. 2001 Feb 1;21(3):RC128. (2001)

Bar-Gad I, Ritov Y, Vaadia E, Bergman H.

Failure in identification of overlapping spikes from multiple neuron activity causes artificial correlations

J Neurosci Methods. 2001 May 30;107(1-2):1-13. (2001)

O. Donchin, A. Gribova, O. Steinberg, H. Bergman, Cardoso S. de Oliveira, E. Vaadia

Local field potentials related to bimanual movements in the primary and supplementary motor cortices

Experimental Brain Research 140(1):46-55 (2001)

Cardoso de Oliveira S, Gribova A, Donchin O, Bergman H, Vaadia E.

Neural interactions between motor cortical hemispheres during bimanual and unimanual arm movements

Eur J Neurosci. 2001 Dec;14(11):1881-96. (2001)

Vaadia E.

Cognitive neuroscience. Learning how the brain learns

Nature. 2000 Jun 1;405(6786):523-5. (2000)

Raz A, Vaadia E, Bergman H.

Firing patterns and correlations of spontaneous discharge of pallidal neurons in the normal and tremulous MPTP Vervet model of Parkinsonism

J Neurosci. 20(22):8559-71. (2000)

Martignon L, Deco G, Laskey K, Diamond M, Freiwald W, Vaadia E.

Neural coding: higher-order temporal patterns in the neurostatistics of cell assemblies

Neural Comput. 2000 Nov;12(11):2621-53. (2000)

Slovin H, Abeles M, Vaadia E, Haalman I, Prut Y, Bergman H.

Frontal cognitive impairments and saccadic deficits in low-dose MPTP-treated monkeys

J Neurophysiol. 1999 Feb;81(2):858-74. (1999)

Donchin O, de Oliveira SC, Vaadia E.

Who tells one hand what the other is doing: the neurophysiology of bimanual movements

Neuron. 1999 May;23(1):15-8. (1999)

Prut Y, Vaadia E, Bergman H, Haalman I, Slovin H, Abeles M.

Spatiotemporal structure of cortical activity: properties and behavioral relevance

J Neurophysiol. 1998 Jun;79(6):2857-74. (1998)

Haalman I, Vaadia E.

Emergence of spatio-temporal patterns in neuronal activity

Z Naturforsch C. 1998 Jul-Aug;53(7-8):657-69. (1998)

Reimann S, Fuster JM, Gierer A, Mayer-Kress G, Neumann T, Roelfsema P, Rotter S, Schöner G, Stephan A, Vaadia E, Walter H.

Functionally Distinct NMDA Receptors Mediate Horizontal Connectivity within Layer 4 of Mouse Barrel Cortex

Z Naturforsch C. 1998 Jul-Aug;53(7-8):770-4. (1998)

Reimann S, Fuster JM, Gierer A, Mayer-Kress G, Neumann T, Roelfsema P, Rotter S, Schöner G, Stephan A, Vaadia E, Walter H.

Group report: emergent properties of natural and artificial systems

Z Naturforsch C. 1998 Jul-Aug;53(7-8):770-4. (1998)

Ehud Ahissar, Moshe Abeles, Merav Ahissar, Sebastian Haidarliu, Eilon Vaadia

Hebbian-like functional plasticity in the auditory cortex of the behaving monkey

Neuropharmacology 37(4-5):633-55 (1998)

Bergman H, Feingold A, Nini A, Raz A, Slovin H, Abeles M, Vaadia E.

Physiological aspects of information processing in the basal ganglia of normal and parkinsonian primates

Trends Neurosci. 1998 Jan;21(1):32-8. (1998)

Donchin O, Gribova A, Steinberg O, Bergman H, Vaadia E.

Primary motor cortex is involved in bimanual coordination

Nature. 1998 Sep 17;395(6699):274-8. (1998)

Haalman I, Vaadia E.

Dynamics of neuronal interactions: relation to behavior, firing rates, and distance between neurons

Hum Brain Mapp. 1997;5(4):249-53. (1997)

Martignon L., Lasky K., Deco, G. and Vaadia E

Learning Exact Patterns of Quasi-synchronization among Spiking Neurons from Data on Multi-unit Recordings

MIT Press, vol. 9, pp: 76-81 (1997)

Raz A, Feingold A, Zelanskaya V, Vaadia E, Bergman H.

Neuronal synchronization of tonically active neurons in the striatum of normal and Parkinsonian primates

J Neurophysiol; 76(3):2083-8. (1996J Neurophysiol; 76(3):2083-8.)

Seidemann E, Meilijson I, Abeles M, Bergman H, Vaadia E.

Simultaneously recorded single units in the frontal cortex go through sequences of discrete and stable states in monkeys performing a delayed localization task

J Neurosci. 1996 Jan 15;16(2):752-68. (1996)

Vaadia E, Aertsen A, Nelken I.

‘Dynamics of neuronal interactions’ cannot be explained by ‘neuronal transients’

Proc Biol Sci. 1995 Sep 22;261(1362):407-10. (1995)

Abeles M, Bergman H, Gat I, Meilijson I, Seidemann E, Tishby N, Vaadia E.

Cortical activity flips among quasi-stationary states

Proc Natl Acad Sci U S A. 1995 Sep 12;92(19):8616-20. (1995)

Vaadia E, Haalman I, Abeles M, Bergman H, Prut Y, Slovin H, Aertsen A.

Dynamics of neuronal interactions in monkey cortex in relation to behavioural events

Nature. 1995 Feb 9;373(6514):515-8. (1995)

Nelken I, Prut Y, Vaadia E, Abeles M.

In search of the best stimulus: an optimization procedure for finding efficient stimuli in the cat auditory cortex

Hear Res. 1994 Jan;72(1-2):237-53. (1994)

Nelken I, Prut Y, Vaadia E, Abeles M.

Population responses to multifrequency sounds in the cat auditory cortex: one- and two-parameter families of sounds

Hear Res. 1994 Jan;72(1-2):206-22. (1994)

Abeles M, Prut Y, Bergman H, Vaadia E.

Synchronization in neuronal transmission and its importance for information processing

Prog Brain Res. 1994;102:395-404. (1994)

Abeles M, Bergman H, Margalit E, Vaadia E.

Spatiotemporal firing patterns in the frontal cortex of behaving monkeys

J Neurophysiol. 1993 Oct;70(4):1629-38. (1993)

Ahissar E, Vaadia E, Ahissar M, Bergman H, Arieli A, Abeles M.

Dependence of cortical plasticity on correlated activity of single neurons and on behavioral context

Science. 1992 Sep 4;257(5075):1412-5. (1992)

Ahissar M, Ahissar E, Bergman H, Vaadia E.

Encoding of sound-source location and movement: activity of single neurons and interactions between adjacent neurons in the monkey auditory cortex

J Neurophysiol. 1992 Jan;67(1):203-15. (1992)

Aertsen A, Vaadia E, Abeles M, Ahissar E, Bergman H, Karmon B, Lavner Y, Margalit E, Nelken I, Rotter S.

Neural interactions in the frontal cortex of a behaving monkey: signs of dependence on stimulus context and behavioral state

J Hirnforsch. 1991;32(6):735-43. (1991)

Nelken I, Vaadia E.

A sensitive estimator for crosscorrelograms

Biol Cybern. 1990;64(1):51-60. (1990)

Ahissar E, Vaadia E.

Oscillatory activity of single units in a somatosensory cortex of an awake monkey and their possible role in texture analysis

Proc Natl Acad Sci U S A. 1990 Nov;87(22):8935-9. (1990)

Vaadia E, Bergman H, Abeles M.

Neuronal activities related to higher brain functions–theoretical and experimental implications

IEEE Trans Biomed Eng. 1989 Jan;36(1):25-35. (1989)

Gottlieb Y, Vaadia E, Abeles M.

Single unit activity in the auditory cortex of a monkey performing a short term memory task

Exp Brain Res. 1989;74(1):139-48. (1989)

Vaadia E.

Single-unit activity related to active localization of acoustic and visual stimuli in the frontal cortex of the rhesus monkey

Brain Behav Evol. 1989;33(2-3):127-31. (1989)

Vaadia E, Kurata K, Wise SP.

Neuronal activity preceding directional and nondirectional cues in the premotor cortex of rhesus monkeys

Somatosens Mot Res. 1988;6(2):207-30. (1988)

Vaadia E, Abeles M.

Temporal firing patterns of single units, pairs and triplets of units in the auditory cortex

Isr J Med Sci. 1987 Jan-Feb;23(1-2):75-83. (1987)

Vaadia E, Benson DA, Hienz RD, Goldstein MH Jr.

Unit study of monkey frontal cortex: active localization of auditory and of visual stimuli

J Neurophysiol. 1986 Oct;56(4):934-52. (1986)

Frostig RD, Gottlieb Y, Vaadia E, Abeles M.

The effects of stimuli on the activity and functional connectivity of local neuronal groups in the cat auditory cortex

Brain Res. 1983 Aug 8;272(2):211-21. (1983)

Vaadia E, Gottlieb Y, Abeles M.

Single-unit activity related to sensorimotor association in auditory cortex of a monkey

J Neurophysiol. 1982 Nov;48(5):1201-13. (1982)

Eilon Vaadia

Professor Emeritus

Email: eilon.vaadia@elsc.huji.ac.il

Eilon Vaadia

@eilon_vaadia

Address: The Edmond and Lily Safra Center for Brain Sciences
The Suzanne and Charles Goodman Brain Sciences Building,
Level 2, Room 1205, Edmond J. Safra Campus,
The Hebrew University of Jerusalem, 9190401

Vaadia's Lab

People

Dina Moshitch

Lab Manager

Lital Summer

Lab administrative officer

Samira Souffi

Post Doc

Mousa Karayanni

PhD Student

Sapir Bashari

Ph.D. Student

Nimrod Agassi

M.Sc. Student

Alon Dotan

B.Sc. Student

Ana Polterovich

Alex Kazakov

Moran Aharoni

Kamini Sehrawat

Arthur Berrou

Maciej Jankowski

Johannes Niediek

Ori Brook

Yael Bitterman

Itai Hershenhoren

Yehuda Albeck

Bshara Awwad

Jonathan Rubin

Dina Farkas

Flora Antunes

Eyal Wigderson

Dana Barniv

Ayelet Shapira

Amit Yaron

Alon Fishbach

Tohar Sion Yarden

Shahar Mendelssohn

Mor Harpaz

Tamar Regev

Leila Khouri

Liora Las

Livia de Hoz

Mor Nahum

Nachum Ulanovsky

Nevo Taaseh

Omer Bar-Yosef

Roi Kliper

Gal Chechik

Yaron Rotman

Nadav Amir

Gideon Rothschild

Publications

Eylon Zohar, Israel Nelken, Boaz Rafaely

An Efficient Neural Network for Modeling Human Auditory Neurograms for Speech

ArXiv.org (2026)

Yang Chen, Marinus Kloos, Zsuzsanna Varga, Yonghai Zhang, Inken Piro, Tatsuo K Sato, Bert Sakmann, Israel Nelken, Arthur Konnerth

Thalamic activation of the visual cortex at the single-synapse level

Science (New York, N.Y.) (2026)

S Bashari, MM Jankowski, I Nelken

The representation of regularity and randomness in auditory cortex of awake rats

bioRxiv (2025)

J Niediek, MM Jankowski, A Polterovich, A Kazakov, I Nelken

Insular cortex encodes task alignment

bioRxiv (2024)

Gilday D. O., Praegel B., Maor I., Cohen T., Nelken I., Mizrahi A.

Surround suppression in mouse auditory cortex underlies auditory edge detection

PLoS Computational Biology (2023)

Yarden. T., Mizrahi. A., Nelken I.

Context-Dependent Inhibitory Control of Stimulus-Specific Adaptation

Journal of Neuroscience. (2022)

Rajendran VG, Tsdaka Y, Keung TY, Schnupp JWH, Nelken I.

Rats synchronize predictively to metronomes

iScience, in press (2023)

Polterovich, A., Jankowski, M.M., Niediek, J., Kazakov, A., Nelken, I.

bioRxiv (2024)

Sehrawat, K., Nelken, I.

Sound preferences in mice are sex-dependent

bioRxiv (2024)

Maciej M. Jankowski , Mousa Karayanni, Mor Harpaz, Ana Polterovich , Israel Nelken

A Rapid Anterior Auditory Processing Stream Through the Insulo-Parietal Auditory Field in the Rat

bioRxiv (2023)

Kenneth W. Latimer, Dylan Barbera, Michael Sokoletsky, Bshara Awwad, Yonatan Katz, Israel Nelken, Ilan Lampl, Adriene L. Fairhall, Nicholas J. Priebe

Multiple Timescales Account for Adaptive Responses across Sensory Cortices

The Journal of Neuroscience (2020)

Maciej M. Jankowski, Ana Polterovich, Alex Kazakov, Johannes Niediek, Israel Nelken

An automated, low-latency environment for studying the neural basis of behavior in freely moving rats

BMC Biology (2023)

Bshara Awwad, Maciej M. Jankowski, Ana Polterovich, Sapir Bashari, Israel Nelken

Extensive representation of sensory deviance in the responses to auditory gaps in unanesthetized rats

Current Biology (2023)

Oren Amsalem, James King, Michael Reimann, Srikanth Ramaswamy, Eilif Muller, Henry Markram, Israel Nelken, Idan Segev

Dense Computer Replica of Cortical Microcircuits Unravels Cellular Underpinnings of Auditory Surprise Response

bioRxiv (2020)

Atlan G. Terem A. Peretz-Rivlin N., Sehrawat, K. Gonzales, B., Goll Y., Pozner G., Tasaka G., Goll Y., Rafaeli R., Zviran O., Lim B., Groysman M., Goshen I, Mizrahi A., Nelken I., Citri A.

The claustrum supports resilience to distraction

Current Biology (2018)

Mizrahi A., Shalev A. Nelken I.

Single neuron and population coding of natural sounds in auditory cortex

Current Opinion in Neurobiology (2014)

Rothschild G, Cohen L, Mizrahi A, Nelken I.

Elevated correlations in neuronal ensembles of mouse auditory cortex following parturition

J Neurosci. (2013)

Nadav Amir, Naftali Tishby, Israel Nelken

A simple model of the attentional blink and its modulation by mental training

PLOS Computational Biology, e1010398 (2022)

Mousa Karayanni & Israel Nelken

Extrinsic rewards, intrinsic rewards, and non-optimal behavior

Journal of Computational Neuroscience volume 50, pages139–143 (2022)

Lior Madmoni, Shir Tibor, Israel Nelken, Boaz Rafaely

The Effect of Partial Time-Frequency Masking of the Direct Sound on the Perception of Reverberant Speech

IEEE/ACM Transactions on Audio, Speech, and Language Processing, 29, 2037-2047 (2021)

Nadav Amir, Reut Suliman-Lavie, Maayan Tal, Sagiv Shifman, Naftali Tishby, Israel Nelken

Value-complexity tradeoff explains mouse navigational learning

PLOS Computational Biology 16(12): e1008497 (2020)

Carsten H. Tischbirek, Takahiro Noda, Manabu Tohmi, Antje Birkner, Israel Nelken, Arthur Konnerth

In Vivo Functional Mapping of a Cortical Column at Single-Neuron Resolution

Cell Reports 27 (5), 1319-1326. e5 (2019)

Huang,Shun-Ho, Shmoel,Nava, Jankowski, Maciej M., Erez, Hadas, Sharon,Aviv, Abu-Salah,Wesal, Nelken,Israel, Weiss,Aryeh, Spira,Micha E.

Immunohistological and Ultrastructural Study of the Inflammatory Response to Perforated Polyimide Cortical Implants: Mechanisms Underlying Deterioration of Electrophysiological Recording Quality

Frontiers in neuroscience 14, 926 (2020)

Meng Wang, Xiang Liao, Ruijie Li, Shanshan Liang, Ran Ding, Jingcheng Li, Jianxiong Zhang, Wenjing He, Ke Liu, Junxia Pan, Zhikai Zhao, Tong Li, Kuan Zhang, Xingyi Li, Jing Lyu, Zhenqiao Zhou, Zsuzsanna Varga, Yuanyuan Mi, Yi Zhou, Junan Yan, Shaoqun Zeng, Jian K. Liu, Arthur Konnerth, Israel Nelken, Hongbo Jia & Xiaowei Chen

Single-neuron representation of learned complex sounds in the auditory cortex

Nature Communications 11 (1), 1-14 (2020)

Israel Nelken

From neurons to behavior: the view from auditory cortex

Current Opinion in Physiology 18, 37-41 (2020)

Israel Nelken

Neural Population Coding of Natural Sounds in Non-flying Mammals

Oxford Research Encyclopedia of Neuroscience (2017)

Itai Hershenhoren, Israel Nelken

Detection of Tones Masked by Fluctuating Noise in Rat Auditory Cortex

Cerebral Cortex 27 (11), 5130-5143 (2016)

Alainde Cheveigné, Israel Nelken

Filters: When, Why, and How (Not) to Use Them

Neuron 102 (2), 280-293 (2019)

Eban E., Rothschild G., Mizrahi A., Nelken I., Elidan G.

Dynamic copula networks for modeling real-valued time series

Artificial Intelligence and Statistics (2013)

Tamar I Regev, Geffen Markusfeld, Leon Y Deouell, Israel Nelken

Context sensitivity across multiple time scales with a flexible frequency bandwidth

Cerebral Cortex 32 (1), 158-175 (2022)

Rothschild G, Nelken I, Mizrahi A.

Functional organization and population dynamics in the mouse primary auditory cortex

Nat Neurosci. 2010 Mar;13(3):353-60. (2010)

Mor Harpaz, Maciej M. Jankowski, Leila Khouri, Israel Nelken

Emergence of abstract sound representations in the ascending auditory system

Progress in Neurobiology, Volume 202, 102049, ISSN 0301-0082 (2021)

Bshara Awwad, Maciej M Jankowski, Israel Nelken

Synaptic Recruitment Enhances Gap Termination Responses in Auditory Cortex

Cerebral Cortex Volume 30, Issue 8, August 2020, Pages 4465–4480 (2020)

Regev, TI, Nelken I, Deouell LY.

Evidence for Linear but Not Helical Automatic Representation of Pitch in the Human Auditory System.

Journal of Cognitive Neuroscience Early Access p.1-17 (2019)

Busche, M A, Wegmann S, Dujardin S, Commins C, Schiantarelli J, Klickstein N, Kamath TV, Carlson GA, Nelken I, Hyman BT.

Tau impairs neural circuits, dominating amyloid-β effects, in Alzheimer models in vivo.

Nat Neurosci (2019)

Kazakov, A, Nelken I.

Acoustic calibration in an echoic environment.

Journal of Neuroscience Methods Volume 309, Pages 60-70 (2018)

Kazakov A, Jankowski MM, Nelken I.

Acoustic recordings data from an echoic environment and a toolkit for its analysis

Data Brief. 21:1451-1457 (2018)

de Hoz, L, Gierej D, Lioudyno V, Jaworski J, Blazejczyk M, Cruces-Solís H, Beroun A, Lebitko T, Nikolaev T, Knapska E, Nelken I, Kaczmarek L.

Blocking c-Fos Expression Reveals the Role of Auditory Cortex Plasticity in Sound Frequency Discrimination Learning.

Cerebral Cortex, Volume 28, Issue 5, Pages 1645–1655 (2018)

Polterovich A, Jankowski MM, Nelken I.

Deviance sensitivity in the auditory cortex of freely moving rats

PLoS One. 13(6):e0197678 (2018)

Keskin AD, Kekuš M, Adelsberger H, Neumann U, Shimshek DR, Song B, Zott B, Peng T, Förstl H, Staufenbiel M, Nelken I, Sakmann B, Konnerth A, Busche M A.

BACE inhibition-dependent repair of Alzheimer’s pathophysiology

Proc Natl Acad Sci U S A. 114(32):8631-8636 (2017)

Li J, Liao X, Zhang J, Wang M, Yang N, Zhang J, Lv G, Li H, Lu J, Ding R, Li X, Guang Y, Yang Z, Qin H, Jin W, Zhang K, He C, Jia H, Zeng S, Hu Z, Nelken I, Chen X.

Primary Auditory Cortex is Required for Anticipatory Motor Response

Cereb Cortex; 27(6):3254-3271 (2017)

Yarden TS, Nelken I.

Stimulus-specific adaptation in a recurrent network model of primary auditory cortex

PLoS Comput Biol. 3(3):e1005437 (2017)

Grimm, S, Escera C, Nelken I.

Early indices of deviance detection in humans and animal models.

Biological Psychology Volume 116, Pages 23-27 (2016)

Wigderson, E, Nelken I, Yarom Y.

Early multisensory integration of self and source motion in the auditory system.

Proc Natl Acad Sci U S A, 113(29): 8308–8313 (2016)

Jonathan Rubin, Nahum Ulinovsky, Israel Nelken and Naftali Tishby

The Representation of Prediction Error in Auditory Cortex

PLoS Comput Biol 12(8) e1005058 (2016)

Barniv D, Nelken I.

Auditory Streaming as an Online Classification Process with Evidence Accumulation

PLoS One. 2015 Dec 15;10(12):e0144788. (2015)

Khouri L, Nelken I.

Detecting the unexpected

Curr Opin Neurobiol. 2015 Dec;35:142-7. (2015)

Slomowitz E, Styr B, Vertkin I, Milshtein-Parush H, Nelken I, Slutsky M, Slutsky I.

Interplay between population firing stability and single neuron dynamics in hippocampal networks

https://doi.org/10.7554/eLife.04378 (2015)

Busche MA, Kekuš M, Adelsberger H, Noda T, Förstl H, Nelken I, Konnerth A.

Rescue of long-range circuit dysfunction in Alzheimer’s disease models

Nat Neurosci. 2015 Nov;18(11):1623-30. (2015)

Nelken I.

Stimulus-specific adaptation and deviance detection in the auditory system: experiments and models

Biol Cybern. 2014 Oct;108(5):655-63. (2014)

Moshitch D, Nelken I.

The Representation of Interaural Time Differences in High-Frequency Auditory Cortex

Cereb Cortex. 2016 Feb;26(2):656-68. (2014)

Xu X, Yu X, He J, Nelken I.

Across-ear stimulus-specific adaptation in the auditory cortex

Front Neural Circuits. 2014 Jul 30;8:89. (2014)

Nelken I, Bizley J, Shamma SA, Wang X.

Auditory cortical processing in real-world listening: the auditory system going real

J Neurosci. 2014 Nov 12;34(46):15135-8. (2014)

Israel Nelken, Jennifer Bizley, Shihab A. Shamma, and Xiaoqin Wang

Auditory cortical processing in real-world listening: the auditory system going real

J Neurosci. 2014 Nov 12; 34(46): 15135–15138. (2014)

de Hoz L, Nelken I.

Frequency tuning in the behaving mouse: different bandwidths for discrimination and generalization

PLoS One. 2014 Mar 14;9(3):e91676. (2014)

Itai Hershenhoren, Nevo Taaseh, Flora M. Antunes and Israel Nelken

Intracellular correlates of stimulus-specific adaptation

Journal of Neuroscience 26 February 2014, 34 (9) 3303-3319. (2014)

Grodzinsky Y., Nelken I.

The neural code that makes us human

Science. 2014 Feb 28;343(6174):978-9. (2014)

Moshitch D, Nelken I.

Using Tweedie distributions for fitting spike count data

J Neurosci Methods. 2014 Mar 30;225:13-28. (2014)

Nelken I, de Cheveigné A.

An ear for statistics

Nat Neurosci. 2013 Apr;16(4):381-2. (2013)

Nelken I, Yaron A, Polterovich A, Hershenhoren I.

Stimulus-specific adaptation beyond pure tones

Adv Exp Med Biol. 2013;787:411-8. (2013)

Eitan Globerson, and Israel Nelken

The neuro-pianist

Front Syst Neurosci. 2013; 7: 35. (2013)

Chechik G, Nelken I.

Auditory abstraction from spectro-temporal features to coding auditory entities

Proc Natl Acad Sci U S A. 2012 Nov 13;109(46):18968-73. (2012)

Nelken I.

Predictive information processing in the brain: the neural perspective

Int J Psychophysiol. 2012 Feb;83(2):253-5. (2012)

Yaron A, Hershenhoren I, Nelken I.

Sensitivity to Complex Statistical Regularities in Rat Auditory Cortex

Neuron. 2012 Nov 8;76(3):603-15. (2012)

Grienberger C, Adelsberger H, Stroh A, Milos RI, Garaschuk O, Schierloh A, Nelken I, Konnerth A.

Sound-evoked network calcium transients in mouse auditory cortex in vivo

J Physiol. 2012 Feb 15;590(4):899-918. (2012)

Zohar O, Shackleton TM, Nelken I, Palmer AR, Shamir M.

First spike latency code for interaural phase difference discrimination in the guinea pig inferior colliculus

J Neurosci. 2011 Jun 22;31(25):9192-204. (2011)

Chen X, Leischner U, Rochefort NL, Nelken I, Konnerth A.

Functional mapping of single spines in cortical neurons in vivo

Nature. 2011 Jun 26;475(7357):501-5. (2011)

Israel Nelken

Music and the auditory brain: where is the connection?

Front Hum Neurosci. 2011; 5: 106. (2011)

Taaseh N, Yaron A, Nelken I.

Stimulus-specific adaptation and deviance detection in the rat auditory cortex

PLoS One. 2011;6(8):e23369. (2011)

Asadollahi A, Endler F, Nelken I, Wagner H.

Neural correlates of binaural masking level difference in the inferior colliculus of the barn owl (Tyto alba)

Eur J Neurosci. 2010 Aug;32(4):606-18. (2010)

Nahum M, Nelken I, Ahissar M.

Stimulus uncertainty and perceptual learning: similar principles govern auditory and visual learning

Vision Res. 2010 Feb 22;50(4):391-401. (2010)

Antunes FM, Nelken I, Covey E, Malmierca MS.

Stimulus-specific adaptation in the auditory thalamus of the anesthetized rat

PLoS One. 2010 Nov 19;5(11):e14071. (2010)

Nelken I.

Inhibitory plasticity in auditory cortex

Neuron. 2009 Jun 11;62(5):605-7. (2009)

Winkler I, Denham SL, Nelken I.

Modeling the auditory scene: predictive regularity representations and perceptual objects

Trends Cogn Sci. 2009 Dec;13(12):532-40. (2009)

Merav Ahissar , Mor Nahum , Israel Nelken and Shaul Hochstein

Reverse hierarchies and sensory learning

Philosophical transactions of the Royal Society of London. Series B, Biological sciences (2009)

Andrew J King, Israel Nelken

Unraveling the principles of auditory cortical processing: can we learn from the visual system?

Nature Neuroscience volume 12, pages 698–701 (2009) (2009)

Parush N, Arkadir D, Nevet A, Morris G, Tishby N, Nelken I, Bergman H.

Encoding by response duration in the basal ganglia

J Neurophysiol. 2008 Dec;100(6):3244-52. (2008)

Las L, Shapira AH, Nelken I.

Functional gradients of auditory sensitivity along the anterior ectosylvian sulcus of the cat

J Neurosci. 2008 Apr 2;28(14):3657-67. (2008)

Nahum M, Nelken I, Ahissar M.

Low-level information and high-level perception: the case of speech in noise

PLoS Biol. 2008 May 20;6(5):e126. (2008)

Israel Nelken and Omer Bar-Yosef

Neurons and objects: the case of auditory cortex

Front Neurosci. 2008 Jul; 2(1): 107–113. (2008)

Nelken I, Bizley JK, Nodal FR, Ahmed B, King AJ, Schnupp JW.

Responses of auditory cortex to complex stimuli: functional organization revealed using intrinsic optical signals

J Neurophysiol. 2008 Apr;99(4):1928-41. (2008)

Gordon N, Shackleton TM, Palmer AR, Nelken I.

Responses of neurons in the inferior colliculus to binaural disparities: Insights from the use of Fisher information and mutual information

J Neurosci Methods. 2008 Apr 30;169(2):391-404. (2008)

Yuval-Greenberg S, Tomer O, Keren AS, Nelken I, Deouell LY.

Transient induced gamma-band response in EEG as a manifestation of miniature saccades

Neuron. 2008 May 8;58(3):429-41. (2008)

Y. Bitterman, R. Mukamel, R. Malach, I. Fried & I. Nelken

Ultra-fine frequency tuning revealed in single neurons of human auditory cortex

Nature volume 451, pages 197–201 (10 January 2008) (2008)

Nelken I, Chechik G.

Information theory in auditory research

Hear Res. 2007 Jul;229(1-2):94-105. (2007)

Israel Nelken, Nachum Ulanovsky

Mismatch negativity and stimulus-specific adaptation in animal models

Journal of Psychophysiology 21(3-4):214-223 (2007)

Bizley JK, Nodal FR, Bajo VM, Nelken I, King AJ.

Physiological and anatomical evidence for multisensory interactions in auditory cortex

Cereb Cortex. 2007 Sep;17(9):2172-89. (2007)

Alex Loebel, Israel Nelken, and Misha Tsodyks

Processing of sounds by population spikes in a model of primary auditory cortex

Front Neurosci. 2007 Nov; 1(1): 197–209. (2007)

Omer Bar-Yosef and Israel Nelken

The Effects of Background Noise on the Neural Responses to Natural Sounds in Cat Primary Auditory Cortex

Front Comput Neurosci. 2007; 1: 3. (2007)

Israel Nelken, Merav Ahissar

High-Level and Low-Level Processing in the Auditory System: The Role of Primary Auditory Cortex

IOS Press (2006)

Chechik G, Anderson MJ, Bar-Yosef O, Young ED, Tishby N, Nelken I.

Reduction of information redundancy in the ascending auditory pathway

Neuron. 2006 Aug 3;51(3):359-68. (2006)

Moshitch D, Las L, Ulanovsky N, Bar-Yosef O, Nelken I.

Responses of neurons in primary auditory cortex (A1) to pure tones in the halothane-anesthetized cat

J Neurophysiol. 2006 Jun;95(6):3756-69. (2006)

Nelken I, Chechik G, Mrsic-Flogel TD, King AJ, Schnupp JW.

Encoding stimulus information by spike numbers and mean response time in primary auditory cortex

J Comput Neurosci. 2005 Oct;19(2):199-221. (2005)

Bizley JK, Nodal FR, Nelken I, King AJ.

Functional Organization of Ferret Auditory Cortex

Cereb Cortex. 2005 Oct;15(10):1637-53. (2005)

Liora Las, Edward A. Stern and Israel Nelken

Representation of tone in fluctuating maskers in the ascending auditory system

Journal of Neuroscience 9 February 2005, 25 (6) 1503-1513; (2005)

Griffiths TD, Warren JD, Scott SK, Nelken I, King AJ.

Cortical processing of complex sound: a way forward?

Trends Neurosci. 2004 Apr;27(4):181-5. (2004)

Nelken I, Bizley JK, Nodal FR, Ahmed B, Schnupp JW, King AJ.

Large-scale organization of ferret auditory cortex revealed using continuous acquisition of intrinsic optical signals

J Neurophysiol. 2004 Oct;92(4):2574-88. (2004)

Nachum Ulanovsky, Liora Las, Dina Farkas and Israel Nelken

Multiple time scales of adaptation in auditory cortex neurons

Journal of Neuroscience 17 November 2004, 24 (46) 10440-10453; (2004)

Nelken I.

Processing of complex stimuli and natural scenes in the auditory cortex

Curr Opin Neurobiol. 2004 Aug;14(4):474-80. (2004)

Fishbach A, Yeshurun Y, Nelken I.

Neural model for physiological responses to frequency and amplitude transitions uncovers topographical order in the auditory cortex

J Neurophysiol. 2003 Dec;90(6):3663-78. (2003)

Open Positions

A postdoctoral position is available in the field of auditory perception under the supervision of Prof. Israel Nelken. Click here for more information.

Additional Information

Honors:
1985 The A. Heller prize for excellence in Research Thesis
1991 Fullbright fellowship
1994 The Bergmann Memorial Research Grant (concurrently with BSF grant No. 93-00057)
1999 Research prize of the Faculty of Medicine, Hebrew University – Hadassah Medical School.
2000 Bernard Katz Lecturer for the year 2000
2008 Michael Bruno prize, administered by Yad-Hanadiv foundation
2015 Rector prize for excellence in research and teaching
2016 The Michael Landau prize for the Sciences and Research
2021 Humboldt research prize

Israel Nelken

Professor

Email: israel.nelken@mail.huji.ac.il

Phone: +972-2-6584229

Fax: +972-2-6586077

Israel Nelken

Address: The Edmond and Lily Safra Center for Brain Sciences
The Suzanne and Charles Goodman Brain Sciences Building,
Level 2, Room 1207, Edmond J. Safra Campus,
The Hebrew University of Jerusalem, 9190401