Baruch Minke Lab

ELSC Members

Research Group of TRP Channels in Vision and Pain

My investigations have created a new field of research. I co-discovered a new type of ion channel, which I designated the Transient Receptor Potential or in short the TRP channel, as a result of my studies on phototransduction and vision in fruit flies (Drosophila melanogaster). I investigated the biophysical and biochemical properties of TRP channels in fruit fly eyes and identified together with the late Prof. Zvi Selinger phospholipase C as a crucial component of the Drosophila TRP signaling pathway. The principles that we found are common to numerous sensory (e.g. temperature, pain and taste sensations) and motor systems (properties of Purkinje neurons in the cerebellum), thus laying the foundation for the study of molecules that underlie mechanisms of TRP and pain, originally initiated by Prof. David Julius. Today we have extended our research to the first identified loss of function mutation in human TRPV1 channel that govern at least several of the human body's regulatory processes related inflammatory pain and to noxious heat detection. Our major aim is to decipher the critical roles of TRP channels in invertebrate vision and of TRPV1 in human somatosensory physiology.

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Baruch Minke

Professor Emeritus

Email: baruchm@ekmd.huji.ac.il
Phone: +972-2-6758407
Fax: +972-2-6439736
Mobile: +972-54-7961151
Baruch Minke CV
Address: Department of Medical Neurobiology, Faculty of Medicine,
Hadassah Ein-Kerem Campus, The Hebrew University of Jerusalem
Research Group of TRP Channels in Vision and Pain
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Ariel Furstenberg PhD
Research Associate
Kadmon J, Timcheck J and Ganguli S

Predictive coding in balanced neural networks with noise

chaos and delays, NeurIPS (2020)

Bahri Y, Kadmon J, Pennington J, Schoenholz S, Sohl-Dickstein J and Ganguli

Statistical mechanics of deep learning

Annual Review of Condensed Matter Physic,501-528,11 (2020)

Wagner MJ, Kim TH, Kadmon J, Nguyen ND, Ganguli S, Schnitzer MJ and Luo L

Cortex-cerebellum dynamics in the execution and learning of a motor task

Cell, Volume 177, Issue 3, Pages 669-682.e24, ISSN 0092-8674, (2019)

Marshel, Kim, Machado, Quirin, Kadmon, Benson, Raja, Chibukhchyan, Ramakrishnan, Inoue, Shane, McKnight, Susumu, Kato, Ganguli and Deisseroth

Layer-specific neural ensembles contributing to ignition and plasticity of perception

Science, Vol. 365, Issue 6453, eaaw5202 (2019)

Kadmon J and Ganguli S

Statistical Mechanics of Low-Rank Tensor Decomposition

NeurIPS (2018)

Kadmon J and Sompolinsky H

Optimal architectures in a solvable model of deep networks

NeurIPS  (2016)

Kadmon J and Sompolinsky, H

Transition to Chaos in Random Neuronal Networks

Phys. Rev. X, 5, 041030 (2015)

Looking for postdoctoral researchers and students at all levels and with an analytical background and passion for science
ELSC Program in Theoretical Neuroscience
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Jonathan Kadmon

Assistant Professor

Email: jonathan.kadmon@mail.huji.ac.il
Jonathan Kadmon
@kadmonj
Address: The Edmond and Lily Safra Center for Brain Sciences
The Suzanne and Charles Goodman Brain Sciences Building,
Edmond J. Safra Campus,
The Hebrew University of Jerusalem, 9190401
https://www.neuro-theory.org
לחצו למעבר להרשמה

“Working memory”

New exhibition titled “Working memory” by the artist Alon kedem and in collaboration with ELSC Prof. Leon Deouell. In the picture: Moshe Lion, the mayor of Jerusalem and Prof. Asher Cohen, the president of The Hebrew University of Jerusalem.