Conducting MRI Research
Labs that are interested in conducting research with ELSC’s Neuroimaging Unit (ENU), must register with us to become users. Each lab is required to choose one member as their 'Lab Coordinator'. This person is in charge of submitting requests and must be familiar with all the following:
- Helsinki submission procedure.
- The “Matarot” software.
- Hadassah Helsinki committee policy.
- The full policy of Clinical Investigation of “Clinical Trials of Human Subjects" from the Ministry of health website.
All researchers within a lab must conduct their research according to the ENU working guidelines and safety policy (File in English), as well as these Helsinki regulation & updates, and complete a GCP Online Course (see instructions in the bottom, 'adding a new researcher').
Procedure to become a User:
Step 1 → Helsinki Approval Step 2 → Becoming an ENU User
Step 1. Submit a New Helsinki Request:
- Fill an 'ENU protocol request summary' and an 'ENU protocol format' and then send them to the ENU committee for approval. The ENU committee meets once a month.
- Once approved by the ENU committee, schedule a meeting with the Helsinki Unit Coordinator to enter your request through the "Matarot" software.
- You will then receive forms that need to be signed by the Lab staff.
- Submit the signed forms (and other material, e.g. GCP diplomas) to the Unit Coordinator for further signatures.
- Once all the signatures are received, the request will be submitted for approval to the Hadassah Helsinki committee. It takes 3-5 weeks from the moment of submission
- It is the Lab coordinator’s responsibility to check the status of their request with the ENU Helsinki Coordinato
- Please note that this procedure inclures corrections and signatures at multiple stages and therefore may take additional time to complete.
Step 2. Becoming an ENU User
Once the request is approved by the Hadassah Helsinki Committee, the research laboratory will be permitted to complete the process to become an ENU user.
The Lab Coordinator will contact (mail or phone) the ENU office in order to:
- Open an account in the ENU Reservation System. The lab will receive a user name and a temporary password.
- Meet with the ENU Director (and sometimes the unit's physicist as well) in order to build/approve the scanning sequences.
- Deposit money (tofes 29 or directly to ENU Budget), for MRI use.
- Verify that the researchers' names are regeistered on the lab's Helsinki approval (i.e. the name of the lab members running the experiment).
- Make sure the researchers complete the ENU Safety Training Course and reads the ENU working guidelines and safety policy (File in English)
- Only after completing steps 4-5 will a researcher be alowed to use the MRI and be registered as an ENU Operator!
- Finally, in order to receive all ENU updates (e.g. canceled scanning slots), all ENU Users and Operators must register to the enu-ops mailing list.
Changing an approved Helsinki:
Making changes to protocol / informed consent form:
1. The Lab’s Helsinki coordinator must schedule a meeting with the ENU Helsinki coordinator, to make the requested changes via the ‘Matarot’ software.
2. The ENU Helsinki coordinator is then responsible to get the necessary signatures from Hadassah and submit it to the Hadassah Helsinki committee. (Changes to an Approved Helsinki are done on a weekly basis).
Adding a new researcher:
1. When adding new researchers, a valid GCP diploma should be obtained by the researcher prior to the application. To obtain the diploma go to the CITI Program site. Once inside, you should click on 'Register', choose 'Participating Institutions' and select or enter 'Hebrew University'. Once you complete the creation of your personal account you will be eligible to take the GCP course free of charge. Returning users can simply login.
3. The Lab’s Helsinki coordinator must schedule a meeting with the ENU Helsinki coordinator, to make the requested changes via the ‘Matarot’ software.
4. The ENU Helsinki coordinator is then responsible to get the necessary signatures from Hadassah and submit it to the Hadassah Helsinki committee. (Changes to an Approved Helsinki are done on a weekly basis).
5. The researcher should register for the next safety training of the ENU, and pass the exam.
6. Once the Helsinki committee approved the addition and the researcher has passed the ENU exam, the researcher's name will be added to the ENU system as an operator. The researcher can now book slots and start scanning.
All requests and inquiries should be submitted through the Helsinki unit coordinator, Lee Ashkenazi (email@example.com)