Ben Katz PhD

Ben Katz PhD

Research Associate

PhD. Neurobiology, B.Sc. Mathematics and Philosophy.

Interested in Signal transduction, Sensory physiology, Vision, Human Physiology and Neurophysiology, Pain, physiology, Biophysics of channels and transporters, DNA origami, DNA and RNA aptamers.

CV

Supervisors

Contact information

Department of Medical Neurobiology and The Edmond and Lily Safra Center for Brain Sciences. The Hebrew University. Hadassah Ein Kerem, Jerusalem 91120, Israel

Recent publications

1. TRPM2 Mediates Neutrophil Killing of Disseminated Tumor Cells

Gershkovitz M, Caspi Y, Fainsod-Levi T, Katz B, Michaeli J, Khawaled S, Lev S, Polyansky L, Shaul ME, Sionov RV, Cohen-Daniel L, Aqeilan RI, Shaul YD, Mori Y, Karni R, Fridlender ZG, Binshtok AM, Granot Z.

Cancer Res. 2018 May 15;78(10):2680-2690.

 

2. Ultrafast optical recording reveals distinct capsaicin-induced ion dynamics along single nociceptive neurite terminals in vitro.

Goldstein RH, Katz B, Lev S, Binshtok AM.

Journal of Biomedical Optics 2017 Jul 1;22(7):76010.

 

3. The Role of Kv7/M Potassium Channels in Controlling Ectopic Firing in Nociceptors.

Barkai O, Goldstein RH, Caspi Y, Katz B, Lev S, Binshtok AM.

Frontiers in Molecular Neuroscience 2017 Jun 13;10:181.

 

4. Depletion of Membrane Cholesterol Suppresses Drosophila Transient Receptor Potential-Like (TRPL) Channel Activity.

Peters M, Katz B, Lev S, Zaguri R, Gutorov R, Minke B.

Current Topics in Membranes 2017;80:233-254.

 

5. The latency of the light response is modulated by the phosphorylation state of Drosophila TRP at a specific site.

Katz B, Voolstra O, Tzadok H, Yasin B, Rhodes-Modrov E, Bartels JP, Strauch L, Huber A, Minke B.

Channels (Austin) 2017 Nov 2;11(6):678-685.

 

6. Electrophysiological Method for Whole-cell Voltage Clamp Recordings from Drosophila Photoreceptors.

Katz B*, Gutorov R*, Rhodes-Mordov E, Hardie RC, Minke B.

*equal contribution

Journal of Visualized Experiments 2017 Jun 13;(124).

 

7. The Phosphorylation State of the Drosophila TRP Channel Modulates the Frequency Response to Oscillating Light In Vivo.

Voolstra O, Rhodes-Mordov E, Katz B, Bartels JP, Oberegelsbacher C, Schotthöfer SK, Yasin B, Tzadok H, Huber A, Minke B.

Journal of Neuroscience. 2017 Apr 12;37(15):4213-4224.

 

8. Ectopic Expression of Mouse Melanopsin in Drosophila Photoreceptors Reveals Fast Response Kinetics and Persistent Dark Excitation.

Yasin B, Kohn E, Peters M, Zaguri R, Weiss S, Schopf K, Katz B, Huber A, Minke B.

Journal of Biological Chemistry 2017 Mar 3;292(9):3624-3636.

 

9. Functional cooperation between the IP3 receptor and phospholipase C secures the light sensitivity to light of Drosophila photoreceptors in vivo

Kohn E, Katz B, Yasin B, Peters M, Rhodes E, Zaguri R, Weiss S, Minke B.

Journal of Neuroscience 2015 Feb 11;35(6):2530-2546

 

10. The role of slow and persistent TTX-resistant sodium currents in acute tumor necrosis factor-a-mediated increase in nociceptors excitability

Gudes S, Barkai O, Caspi Y, Katz B, Lev S, Binshtok AM.

Journal of Neurophysiology 2015 Jan 15;113(2):601-619

 

11. The Drosophila TRP and TRPL are assembled as homomultimeric channels in vivo

Katz B*, Oberacker T*, Richter D, Tzadok H, Peters M, Minke B, and Huber A.

*equal contribution

Journal of Cell Science 2013 May 17

 

12. Compartmentalization and Ca2+ Buffering Are Essential for Prevention of Light-Induced Retinal Degeneration

Weiss S, Kohn E, Dadon D, Katz B, Peters M, Lebendikler M, Kosloff M, Colley N.J, Minke B.

Journal of Neuroscience 2012 Oct 17;32(42):14696-14708

 

13. The activity of the TRP-like channel depends on its expression system.

Lev S*, Katz B*, Minke B.

*equal contribution

Channels (Austin) 2012 Mar-Apr;6(2):86-93.

 

14. Phospholipase C mediated Suppression of Dark Noise Enables Single Photon Detection in Drosophila Photoreceptors

Katz B, Minke B.

Journal of Neuroscience 2012 Feb 22; 32(8):2722-33.

 

 

15. Signal dependent hydrolysis of PI(4,5)P2 without activation of phospholipase C: Implications on the gating of the Drosophila TRPL channel

Lev S, Katz B, Tzarfaty V, Minke B.

Journal of Biological Chemistry 2011 Nov 7.

 

16. Translocation of the Drosophila transient receptor potential-like (TRPL) channel requires both the N- and C-terminal regions together with sustained Ca2+ entry

Richter D*, Katz B*, Oberacker T, Tzarfaty V, Belusic G, Minke B, Huber A.

*equal contribution

Journal of Biological Chemistry 2011 Sep 30; 286 (39):34234-43.

 

17. Membrane lipid modulations remove divalent open channel block from TRP-like and NMDA channels

Parnas M, Katz B, Lev S, Tzarfaty V, Dadon D, Gordon-Shaag A, Metzner H, Yaka R, Minke B.

Journal of Neuroscience 2009 Feb 25; 29 (8):2371-83.

 

18. Open channel block by Ca2+ underlies the voltage dependence of Drosophila TRPL channel

Parnas M*, Katz B*, Minke B.

*equal contribution

Journal of General Physiology 2007 Jan; 129 (1):17-28.

 

Reviews:

 

1. The Drosophila light-activated TRP and TRPL channels - targets of the phosphoinositide signaling cascade

Katz B, Minke B.

Progress in Retinal Research 2018 – sent for review

 

2. TRPC Channels – Insight from the Drosophila Light Sensitive Channels

Katz B, Pak WL, Minke B.

Oxford University Press 2018 – sent for review

 

3. Drosophila photoreceptors and signaling mechanisms

Katz B, Minke B.

Frontiers in Cell Neuroscience 2009 Jun 11; 3:2.

 

Book chapters:

 

1. TRP channel in vision

Katz B, Payne R, Minke B.

Neurobiology of TRP Channels 2017, Sep 7; Pages 27-63, CRC Press Taylor and Francis group

 

2. Genetic Dissection of Invertebrate Phototransduction

Katz B, Minke B.

Encyclopedia of the Eye 2010, Pages 195-206.