Events

ELSC Seminar: Prof. Mouna Maroun - Jan. 25th, 2018 at 17:00

January 25, 2018

ELSC cordially invites you to the lecture given by:

 

 Prof. Mouna Maroun

Sagol Department of Neurobiology, University of Haifa 

 

On the topic of:  

Different effects of environmental and metabolic challenges on mechanisms of learning in juvenile and adult rats”

 

The lecture will be held on Thursday, January 25th, at 17:00

at ELSC: Silberman Bldg., 3rd Wing, 6th Floor,

 Edmond J. Safra Campus 

 

Light refreshments at 16:45

 

Abstract:

Juvenility is a critical developmental stage during which the medial prefrontal cortex (mPFC) undergoes major changes and the brain is vulnerable to environmental factors like stress and/or metabolic challenges. We previously reported that stress affects differently extinction and plasticity in the mPFC in juvenile and adult animals (Schayek and Maroun, 2015). We also showed that exposure to high fat diet (HFD) starting from juvenility for three months resulted in enhanced fear as compared to similar exposure in adult animals that did not affect behavior (Boitard et al., 2015). Together, these point to the vulnerability of the juvenile’s brain.

 

 In a series of experiments that I will present we show that acute exposure a HFD for 10 days during juvenility impairs social recognition memory and LTP in the prefrontal cortex. I will also discuss the differential effect that Oxytocin exert on these processes in juvenile and adult animals.