Events

ELSC Seminar: Ilan Lampl - Nov. 09th, 2017 at 17:00

November 9, 2017

ELSC cordially invites you to the lecture given by:

 

Ilan Lampl

The Weizmann Institute of Science 

On the topic of:

Correlation and decorrelation of synaptic activities in the somatosensory cortex

 

The lecture will be held on Thursday November 09th, 2017 at 17:00

at ELSC: Silberman Bldg., 3rd Wing, 6th Floor,

 Edmond J. Safra Campus  

Light refreshments served at 16:45

Abstract:

One of the major hallmarks of cortical physiology is that the response to repeating presentations of sensory stimulation often varies from trial to trial. Synchronization of ongoing and sensory evoked neuronal activities is another major hallmark of cortical physiology, known since the early EEG studies in animals and humans. Since the variability in the response is correlated among cells, and thus cannot be averaged out, it is unclear how our perception of external sensory stimuli remains stable. The origin of synchrony in early stages of cortical sensory processing is unclear. In this talk I will present our recent in-vivo intracellular studies and show that shared synaptic variability among cells in primary somatosensory cortex of mice is generated de novo in the cortex and is not inherited from ascending thalamic inputs. Furthermore, we found a novel neuromodulatory mechanism that allows the cortex to eliminate shared variable noise without affecting feedforward sensory inputs as expected during activated brain-state.