The Princess and the P: Pluripotent Stem Cells and P-Bodies

In this issue of Cell Stem Cell, Di Stefano et al. (2019) identify the RNA helicase DDX6 as a regulator of stem cell pluripotency and differentiation. DDX6 depletion leads to P-body disruption, which, in turn, inhibits or promotes stem and progenitor cell differentiation, depending on their cellular context.

Viegas JO, Meshorer E
Year of publication
Cell Stem Cell (2019), Volume 25, Issue 5, Pages 589-591