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1973
Minke, B, Hochstein S, Hillman P.  1973.  Early receptor potential evidence for the existence of two thermally stable states in the barnacle visual pigment. The Journal of General Physiology. 62:87–104. Abstract
The early receptor potential {(ERP)} in the barnacle photoreceptor is shown by intracellular recording to exhibit a strong dependence on the color of the stimulus and of the preceding adaptation. The adaptation effects appear to be stable for at least 3 h in the dark. Most strikingly, the {ERP} is positive after red adaptation and mainly negative after blue adaptation. The simplest hypothesis which accounts for these observations is that two thermally stable pigment states with different absorption spectra contribute to the {ERP.} All {ERP} responses appear to be consistent with the sums of different ratios of the {ERP's} of the two pure states. The relative populations of the two states are shown to vary reciprocally, suggesting that the two are states of the same closed pigment cycle. Both states have approximately Dartnall nomogram-shaped absorption spectra, one peaked near 495 nm, and the other near 532 nm.
Hillman, P, Dodge FA, Hochstein S, Knight BW, Minke B.  1973.  Rapid dark recovery of the invertebrate early receptor potential. The Journal of General Physiology. 62:77–86. Abstract
The recovery in the dark of the early receptor potential, as a direct manifestation of the state of the visual pigments, has been studied by intracellular recording in the ventral photoreceptors of Limulus and lateral photoreceptors of Balanus. The recovery is exponential with 1/e time constants of about 80 ms at 24 degrees C for both preparations and 1800 ms at 4 degrees C for Balanus. The 24 degrees C rate extrapolates to total recovery of the pigment within 2 s. The later part of the dark adaptation of the late receptor potential, which may take from seconds to minutes in these preparations, appears thus to be unrelated to the state of the pigment.
Minke, B, Hochstein S, Hillman P.  1973.  Letter: Antagonistic process as source of visible-light suppression of afterpotential in Limulus {UV} photoreceptors. The Journal of General Physiology. 62:787–791.
Hochstein, S, Minke B, Hillman P.  1973.  Antagonistic components of the late receptor potential in the barnacle photoreceptor arising from different stages of the pigment process. 62(1):105-128.
Minke, B, Hochstein S, Hillman P.  1973.  Early receptor potential evidence for the existence of two thermally stable states in the barnacle visual pigment. 62(1):87-104.
Minke, B, Hochstein S, Hillman P.  1973.  Letter: Antagonistic process as source of visible-light suppression of afterpotential in Limulus UV photoreceptors. 62(6):787-791.
Hillman, P, Dodge FA, Hochstein S, Knight BW, Minke B.  1973.  Rapid dark recovery of the invertebrate early receptor potential. 62(1):77-86.
Minke, B, Hochstein S, Hillman P.  1973.  Photoreceptor transduction. A new system. Israel Journal of Medical Sciences. 9 Suppl:114–118.
1972
Hochstein, S, Minke B, Hillman P.  1972.  Receptor potentials from a visual pigment with two thermally stable states. 24:65-73.
Hillman, P, Hochstein S, Minke B.  1972.  A visual pigment with two physiologically active stable states. Science. 175(29):1486-1488.
Hochstein, S, Minke B, Hillman P.  1972.  Receptor potentials from a visual pigment with two thermally stable states. Advances in Experimental Medicine and Biology. 24:65–73.
Hillman, P, Hochstein S, Minke B.  1972.  A visual pigment with two physiologically active stable states. Science {(New} York, {N.Y.)}. 175:1486–1488. Abstract
Red illumination of a Balanus amphitrite photoreceptor that has been adapted to blue light leads to prolonged depolarization in the late receptor potential. This depolarization can be switched off by further exposure to a blue stimulus. The early receptor potential in this cell is purely depolarizing or largely hyperpolarizing; the former is true if the cell has been adapted to red light, and the latter, if blue light has been used. The color-adaptation "memories" for both early and late receptor potentials appear to be permanent. The existence of two stable states for the early receptor potential directly implies a pigment with two stable states, and these apparently contribute antagonistically to the late receptor potential.
1971
Hillman, P, Hochstein S, Minka B.  1971.  Receptor potentials from a pigment system with two stable states. Vision Research. 11:1193.
Soreq, H, Kaplan R.  1971.  Inducible and constitutive -galactosidase formation in cells recovering from protein synthesis inhibition. J Bacteriol. 108:1147-53. Abstract
Inducible and constitutive beta-galactosidase formation and radioactive amino acid incorporation were measured in cells recovering from various treatments which inhibit protein synthesis in the cell. Undelayed beta-galactosidase formation was found in stringent auxotrophs recovering from amino acid starvation, in cells recovering from glycerol or potassium starvation, and in bacteria recovering from puromycin treatment. Delayed beta-galactosidase formation was found in relaxed auxotrophs recovering from amino acid starvation and in prototrophs recovering from chloramphenicol or from tetracycline treatment. The length of this delay was directly proportional to the duration of the treatment. All cells recovering from the various treatments exhibited a slightly decreased rate of beta-galactosidase formation and an increase in radioactive amino acid incorporation.